Gap analysis of pediatric reference intervals related to thyroid hormones and the growth hormone-insulin growth factor axis

Clinical Biochemistry

Volumn 39, Issue 6, 2006, Pages 588-594

  Delvin, Edgard E ^a   Laxmi Grey, Vijay ^b   Vergee, Zulfikarali ^c  

^a UNIVERSITY OF MONTREAL   (Canada)

^b MCMASTER UNIVERSITY MEDICAL CENTRE   (Canada)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Growth hormone; Insulin like growth factor; Pediatric reference values; Thyroid function; Thyrotropin; Thyroxin

Indexed keywords

GROWTH HORMONE; SOMATOMEDIN; THYROID HORMONE;

ADOLESCENCE; BIOCHEMISTRY; BIOLOGICAL ACTIVITY; BIRTH; CANADA; CLINICAL CHEMISTRY; CLINICAL STUDY; DEVELOPMENTAL STAGE; DIAGNOSTIC VALUE; EVOLUTION; FOLLOW UP; GROWTH, DEVELOPMENT AND AGING; HORMONE ACTION; HUMAN; LABORATORY; MEDICAL TECHNOLOGY; NEWBORN PERIOD; PEDIATRICS; PHYSICIAN; PHYSIOLOGY; PRIORITY JOURNAL; PUBERTY; REFERENCE VALUE; RELIABILITY; REVIEW;

EID: 33745205625     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2006.03.006     Document Type: Review

References (82)

1. Pitkanen O.M., and O'Brodovich H.M. Significance of ion transport during lung development and in respiratory disease of the newborn. Ann Med 30 (1998) 134-142
2. Patzak A. Short-term rhythms of the cardiorespiratory system and their significance in neonatology. Chronobiol Int 16 (1999) 249-268
3. Djemli A., Van Vliet G., Belgoudi J., Lambert M., and Delvin E.E. Reference intervals for free thyroxine, total triiodothyronine, thyrotropin and thyroglobulin for Quebec newborns, children and teenagers. Clin Biochem 37 (2004) 328-330
4. Delvin E.E., Salle B.L., Reygrobellet B., Mellier G., and Claris O. Vitamin A and E supplementation in breast-fed newborns. J Pediatr Gastroenterol Nutr 31 (2000) 562-565
5. Salle B.L., Delvin E.E., Lapillonne A., Bishop N.J., and Glorieux F.H. Perinatal metabolism of vitamin D. Am J Clin Nutr 71 (2000) 1317S-1324S
6. Salle B.L., Glorieux F.H., Delvin E.E., David L.S., and Meunier G. Vitamin D metabolism in preterm infants. Serial serum calcitriol values during the first four days of life. Acta Paediatr Scand 72 (1983) 203-206
7. Elefteriou F., and Karsenty G. Bone mass regulation by leptin: a hypothalamic control of bone formation. Pathol Biol (Paris) 52 (2004) 148-153
8. Csermely T., Halvax L., Schmidt E., Zambo K., Vadon G., Szabo I., et al. Occurrence of osteopenia among adolescent girls with oligo/amenorrhea. Gynecol Endocrinol 16 (2002) 99-105
9. Spadano J.L., Bandini L.G., Must A., Dallal G.E., and Dietz W.H. Longitudinal changes in energy expenditure in girls from late childhood through midadolescence. Am J Clin Nutr 81 (2005) 1102-1109
10. Veldhuis J.D., Roemmich J.N., Richmond E.J., Rogol A.D., Lovejoy J.C., Sheffield-Moore M., et al. Endocrine control of body composition in infancy, childhood, and puberty. Endocr Rev 26 (2005) 114-146
11. Fatourechi V., Lankarani M., Schryver P.G., Vanness D.J., Long K.H., and Klee G.G. Factors influencing clinical decisions to initiate thyroxine therapy for patients with mildly increased serum thyrotropin (5.1-10.0 mIU/L). Mayo Clin Proc 78 (2003) 554-560
12. Schiff G.D., Kim S., Krosnjar N., Wisniewski M.F., Bult J., Fogelfeld L., et al. Missed hypothyroidism diagnosis uncovered by linking laboratory and pharmacy data. Arch Intern Med 165 (2005) 574-577
13. England M.L., and Hershman J.M. Serum TSH concentration as an aid to monitoring compliance with thyroid hormone therapy in hypothyroidism. Am J Med Sci 292 (1986) 264-266
14. Gruters A., Jenner A., and Krude H. Long-term consequences of congenital hypothyroidism in the era of screening programmes. Best Pract Res Clin Endocrinol Metab 16 (2002) 369-382
15. Koch C.A., and Sarlis N.J. The spectrum of thyroid diseases in childhood and its evolution during transition to adulthood: natural history, diagnosis, differential diagnosis and treatment. J Endocrinol Invest 24 (2001) 659-675
16. VanVliet G. Thyroid disorders in infancy. In: Lifshitz F. (Ed). Paediatric Endocrinology (2003), Marcer Dekker Inc., New York 347-358
17. Eugène D., Djemli A., and Van Vliet G. Sexual dimorphism of the thyroid function in newborns with congenital hypothyroidism. J Clin Endocrinol Metab 90 (2005) 2696-2700
18. Stahl T.J. Radioimmunoassay and the hormones of thyroid function. Semin Nucl Med 5 (1975) 221-246
19. McBride J.H., Thibeault R.V., and Rodgerson D.O. Thyrotropin as measured by a sensitive immunoradiometric assay. Clin Chem 31 (1985) 1865-1867
20. Chosich N., LeGrand B.A., Topliss D.J., and Stockigt J.R. The significance of subnormal, detectable TSH values: laboratory and clinical aspects. Thyroidology 1 (1989) 79-83
21. Rawlins M.L., and Roberts W.L. Performance characteristics of six third-generation assays for thyroid-stimulating hormone. Clin Chem 50 (2004) 2338-2344
22. Holm S.S., Hansen S.H., Faber J., and Staun-Olsen P. Reference methods for the measurement of free thyroid hormones in blood: evaluation of potential reference methods for free thyroxine. Clin Biochem 37 (2004) 85-93
23. Zurakowski D., Di Canzio J., and Majzoub J.A. Paediatric reference intervals for serum thyroxine, triiodothyronine, thyrotropin, and free thyroxine. Clin Chem 45 (1999) 1087-1091
24. Cioffi M., Gazzero P., Vietri M.T., Magnetta R., Durante A., D'Auria A., et al. Serum concentration of free T3, free T4 and TSH in healthy children. J Pediatr Endocrinol Metab 14 (2001) 1635-1639
25. Butler J., Moore P., Mieli-Vergani G., and Moniz C. Serum free thyroxine and free tri-iodothyronine in normal children. Ann Clin Biochem 25 (1988) 536-539
26. Nelson J.C., Clark S.J., Borut D.L., Tomei R.T., and Carlton E.I. Age-related changes in serum free thyroxine during childhood and adolescence. J Pediatr 123 (1993) 899-905
27. Boquete H.R., Sequera A.M., Celadilla M.L., Holland M., Saskyn N., Cohen A., et al. Immunoradiometric assay of thyrotropin during the first six months of life. Horm Res 41 (1994) 222-224
28. Verheecke P. Free triiodothyronine concentration in serum of 1050 euthyroid children is inversely related to their age. Clin Chem 43 (1997) 963-967
29. Paradis G., Lambert M., O'Loughlin J., Lavallee C., Aubin J., Berthiaume P., et al. The Quebec Child and Adolescent Health and Social Survey: design and methods of a cardiovascular risk factor survey for youth. Can J Cardiol 19 (2003) 523-531
30. Allard P., Delvin E.E., Paradis G., Hanley J.A., O'Loughlin J., Lavallee C., et al. Distribution of fasting plasma insulin, free fatty acids, and glucose concentrations and of homeostasis model assessment of insulin resistance in a representative sample of Quebec children and adolescents. Clin Chem 49 (2003) 644-649
31. Owerbach D., Ruttler W., Martial J., and Baxter J. Genes for growth hormone, chorionic somatommammotropin, and growth hormones-like gene on chromosome 17 in humans. Science 209 (1980) 289-292
32. George D.L., Phillips J., Francke U., and Seeburg P. The genes for growth hormone and chorionic somatomammotropin are on the long arm of human chromosome 17 in region q21 to qter. Hum Genet 57 (1981) 138-141
33. Harper M.E., Barrera-Saldana H.A., and Saunders G.F. Chromosomal localization of the human placental lactogen-growth hormone gene cluster to 17q22-24. Am J Hum Genet 34 (1982) 227-234
34. Baumann G., MacCart J.G., and Amburn K. The molecular nature of circulating growth hormone in normal and acromegalic man. J Clin Endocrin Metab 56 (1983) 946-952
35. Merriam G.R., Carney C., Smith L.C., and Kletke M. Adult growth hormone deficiency: current trends in diagnosis and dosing. J Pediatr Endocrinol Metab 17 Suppl. 4 (2004) 1307-1320
36. Cappa M., and Loche S. Evaluation of growth disorders in the paediatric clinic. J Endocrinol Invest 26 Suppl. 7 (2003) 54-63
37. Wass J.A. Dynamic testing in the diagnosis and follow-up of patients with acromegaly. J Endocrinol Invest 26 Suppl. 7 (2003) 48-53
38. Harvey J.G. Four decades of growth hormone therapy for short children: what have we achieved?. J Clin Endocrinol Metab 84 (1999) 4307-4316
39. Ebdrup L., Fisker S., Holmegaard Sorensen H., Ranke M.B., and Orskov H. Variety in growth hormone determinations due to the use of different immunoassays and to the interference of growth hormone-binding protein. Horm Res 51 Suppl. 1 (1999) 20-26
40. Hauffa B.P., Lehmann N., Bettendorf M., Otto M., Helmuth-Gunther D., Partsch C., et al. Central reassessment of GH concentrations measured at local treatment centres in children with impaired growth: consequences for patient management. Eur J Endocrinol 150 (2004) 291-297
41. Rakover Y., Lavi I., Masalah R., Issam T., Weiner E., and Ben-Shlomo I. Comparison between four immunoassays for growth hormone (GH) measurements as guides to clinical decisions following GH provocative tests. J Pediatr Endocrinol Metab 13 (2000) 637-643
42. Guyda H.J. Growth hormone therapy for non-growth hormone-deficient children with short stature. Curr Opin Pediatr 10 (1998) 416-421
43. Guyda H.J. How do we best measure growth hormone in action?. Horm Res 48 Suppl. 5 (1997) 1-10
44. Carel J.-C., Tresca J.-P., Letrait M., Chaussain J.L., Lebouc Y., Job J.C., et al. Growth hormone testing for the diagnosis of growth hormone deficiency in childhood: a population register-based study. J Clin Endocrinol Metab 82 (1997) 2117-2121
45. Amed S., and on behalf of the Canadian Paediatric Endocrine Group. Comparison of growth hormone immunoassays: relevance for patient care. Horm Res 64 (2005) 62
46. Shalet S.M., Toogood A., Rahim A., and Brennan B.M.D. The diagnosis of growth hormone deficiency in children and adults. Endocr Rev 19 (1998) 203-223
47. Cianfarani S., Tondinelli T., Spadoni G.L., Scirè G., Boemi S., and Boscherini B. Height velocity and IGF-1 assessment in the diagnosis of childhood onset GH insufficiency: do we still need a second GH stimulation test?. Clin Endocrinol 57 (2002) 161-167
48. Collett P.F., and Solberg P. Cohen, genetics, chemistry and function of the IGF/IGFBP system. Endocrine 12 (2000) 121-136
49. Rosenfeld R. The IGF system: New developments relevant to paediatric practice. In: Cianfarani S., Clemmons D.R., and Savage M.O. (Eds). IGF-1 and IGF Binding Proteins: Basic Research and Clinical Management. Endocrine Development vol. 9 (2005), Karger, Basel 1-10
50. Allen D.B. Growth hormone treatment. In: Lifshitz F. (Ed). Paediatric Endocrinology (2003), Marcel Dekker Inc., New York 87-111 Chapter 3
51. Baxter R.C. Circulating binding proteins for the insulin-like growth factors. Trends Endocrinol Metab 4 (1993) 91-96
52. Guler H.P., Zapf J., Schmid C., and Froesch E.R. Insulin-like growth factors I and II in healthy man. Estimation of half-lives and production rates. Acta Endocrinol (Copenh) 121 (1989) 753-758
53. Binoux M., Roghani M., Hossenlop P., Hardouin S., and Gourmelen M. Molecular forms of human IGF binding protein: physiological implications. Acta Endocrinol 124 (1991) 41-47
54. Baxter R.C. Insulin-like growth factor (IGF) binding proteins: the role of serum IGFBPs in regulating IGF availability. Acta Paediatr Scand 124 (1991) 41-47
55. Juul A., and Skakkebaek N.E. Prediction of the outcome of growth hormone provocative testing in short children by measurement of serum levels of IGF-I and IGFBP-3. J Pediatr 130 (1997) 197-204
56. Moore D.C., Ruvalcaba R.H.A., Smith E.K., and Kelly V.C. Plasma somatomedin-C as a screening test for growth hormone deficiency in children and adolescents. Horm Res 16 (1982) 49-55
57. Juul A., Kastrup K.W., Pedersen S.A., and Skakkebaek N.E. GH provocative retesting of 108 young adults with childhood onset GH deficiency and the diagnostic value of IGF-I and IGFBP-3. J Clin Endocrinol Metab 82 (1997) 1195-1201
58. Nunez S.B., Municchi G., Barnes K.M., and Rose S.R. Insulin-like growth factor I (IGF-I), and IGF binding protein-3 concentrations compared to stimulated and night growth hormone in the evaluation of short children. J Clin Endocrinol Metab 81 (1996) 1927-1932
59. Holly J.M.P., Biddlecombe R.A., Dunger D.B., Edge J.A., Amiel S.A., Howell R., et al. Circadian variation of GH-dependent IGF-binding protein in diabetes mellitus and its relationship to insulin. Clin Endocrinol 29 (1998) 667-675
60. Van Vliet G., Styne D.M., Kaplan S.L., and Grumbach M.M. Hormone ontogeny in the ovine fetus. XVI. Plasma immunoreactive somatomedin C/insulin-like growth factor I in the fetal and neonatal lamb and in the pregnant ewe. Endocrinology 113 (1983) 1716-1720
61. Inoue T., Watanabe N., Saito S., Yamasaki M., Saito H., and Shirakawa N. Determination of insulin-like growth factor-I in normal subjects and in patients with growth hormone disorders by radioimmunoassay using biosynthetic homologous peptide. Endocrinol Jpn 33 (1986) 919-927
62. Gargosky S.E., Owens P.C., Walton P.E., Owens J.A., Robinson J.S., Wallace J.C., et al. Most of the circulating insulin-like growth factors-I and -II are present in the 150 kDa complex during human pregnancy. J Endocrinol 131 (1991) 491-497
63. Blum W.F., and Breier B.H. Radioimmunoasays for IGFs and IGFBPs. Growth Regul 4 suppl. 1 (1994) 1-19
64. De Leon D.D., and Asmerom Y. Quantification of insulin-like growth factor I (IGF-I) without interference by IGF binding proteins. Endocrinology 138 (1997) 2199-2202
65. Brabant G., von zur Muhlen A., Wuster C., Ranke M.B., Kratzsch J., Kiess W., et al. Serum insulin-like growth factor I reference values for an automated chemiluminescence immunoassay system: results from a multicenter study. Horm Res 60 (2003) 53-60
66. Elmlinger M.W., Zwirner M., and Kuhnel W. Stability of insulin-like growth factor (IGF)-I and IGF binding protein(IGFBP)-3 measured by the IMMULITE automated chemiluminescence assay system in different blood specimens. Clin Lab 51 (2005) 145-152
67. Frystyk J., Dinesen B., and Orskov H. Non-competitive time-resolved immunofluorometric assays for the determination of human insulin-like growth factor I and II. Growth Regul 5 (1995) 169-176
68. Clemmons D.R. Commercial assays available for insulin-like growth factor I and their use in diagnosing growth hormone deficiency. Horm Res 55 Suppl. 2 (2001) 73-79
69. Ranke M.B., Feldt-Rasmussen U., Bang P., Baxter R.C., Camacho-Hübner C., Clemmons D.R., et al. How should insulin-like growth factor-1 be measured? A consensus statement. Horm Res 55 suppl. 2 (2001) 106-109
70. Blum W.F., Ranke M.B., Kietzmann K., Gauggel E., Zeisel H.J., and Bierich J.R. A specific radioimmunoassay for the growth hormone(GH)-dependent somatomedin-binding protein: Its use for the diagnosis of GH deficiency. J Clin Endocrinol Metab 70 (1990) 1292-1298
71. Blum W.F., and Ranke M.B. Use of insulin-like growth factor-binding protein 3 for the evaluation of growth disorders. Horm Res 33 Suppl. 4 (1990) 31-37
72. Rosenfeld R.G., and Gargosky S.E. Assays for insulin-like growth factors and their binding proteins: practicalities and pitfalls. J Pediatr 128 (1996) S52-S57
73. Jones J.L., and Clemmons D.R. Insulin-like growth factors and their binding proteins. Endocr Rev 16 (1995) 3-34
74. Spagnoli A., Gargosky S.E., Spadoni G.L., MacGillivray M., Oh Y., Boscheneri B., et al. Characterisation of a low molecular weight mass form of insulin-like growth factor binding protein-3 (17.7 kDa) in urine and serum from healthy children and growth hormone-deficient patients. Relationship with GH therapy. J Clin Endocrinol Metab 80 (1995) 3668-3676
75. Tillman V., Buckler J.M.H., Kibirige M.S., Price D.A., Shalet S.M., Wales J.K.H., et al. Biochemical tests in the diagnosis of childhood growth hormone deficiency. J Clin Endocrinol Metab 82 (1997) 531-535
76. Boquete H.R., Sobrado P.G.V., Fideleff H.L., Sequera A.M., Giacco A.V., Suarez M.G., et al. Evaluation of diagnostic accuracy of insulin-like growth factor (IGF)-1 and IGF-binding protein-3 in hormone-deficient children and adults using ROC plot analysis. J Clin Endocrinol Metab 88 (2003) 4702-4708
77. Argente J., Barrios V., Pozo J., Muñoz M.T., Hervás F., Stene M., et al. Normative data for insulin-like growth factors (IGFs), IGF-binding proteins, and growth hormone-binding protein in a healthy Spanish paediatric population: age- and sex-related changes. J Clin Endocrinol Metab 77 (1993) 1522-1528
78. Barrios V., Arjente J., Pozo J., Hervás F., Muñoz M.T., Sánchez J.I., et al. Insulin-like growth factor I, insulin-like growth factor binding proteins, and growth hormone binding protein in Spanish premature and full-term neonates. Horm Res 46 (1996) 130-137
79. Juul A., Dalgaard P., Blum W.F., Bang P., Hall K., Michaelsen K.F., et al. Serum levels of insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) in healthy infants, children, and adolescents: the relation to IGF-I, IGF-II, IGFBP-1, IGFBP-2, age, sex, body mass index, and pubertal maturation. J Clin Endocrinol Metab 80 (1995) 2534-2542
80. Elmlinger M.W., Kühnel W., Weber M.M., and Ranke M.B. Reference ranges for two automated chemiluminescent assays for serum insulin-like growth factor I (IGF-I) and IGF-binding protein 3 (IGFBP-3). Clin Chem Lab Med 42 (2004) 654-664
81. Löfqvist C., Andersson E., Gelander L., Rosberg S., Hulthen L., Blum W.F., et al. Reference values for insulin-like growth factor-binding protein-3 (IGFBP-3) and the ratio of insulin-like growth factor-I to IGFBP-3 throughout childhood and adolescence. J Clin Endocrinol Metab 90 (2005) 1420-1427
82. Karlberg P., and Taranger J. The somatic development of children in a Swedish urban community. Acta Paediatr Scand Suppl 258 (1976) 1-148