Myocardial Metabolism is Better Preserved After Blood Cardioplegia in Infants

Annals of Thoracic Surgery

Volumn 82, Issue 1, 2006, Pages 172-178

  Åmark, Kerstin ^a   Berggren, Håkan ^b   Björk, Kerstin ^b   Ekroth, Annica ^b   Ekroth, Rolf ^b   Nilsson, Krister ^a   Sunnegårdh, Jan ^a  

^a QUEEN SILVIA CHILDREN'S HOSPITAL   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXYBUTYRIC ACID; AMINO ACID; FATTY ACID; GLUTAMIC ACID; LACTIC ACID; LEUCINE; LYSINE;

ARTERIAL BLOOD; ARTICLE; CARDIOPLEGIA; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY SINUS; FEMALE; HEART MUSCLE METABOLISM; HEART SEPTUM DEFECT; HUMAN; INFANT; MALE; PERICARDIAL EFFUSION; PLEURA EFFUSION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

3-HYDROXYBUTYRIC ACID; AMINO ACIDS; AORTA; BICARBONATES; BLOOD; BLOOD GLUCOSE; CALCIUM CHLORIDE; CARDIOPLEGIC SOLUTIONS; CARDIOPULMONARY BYPASS; CORONARY VESSELS; ENERGY METABOLISM; FATTY ACIDS, NONESTERIFIED; FEMALE; HEART ARREST, INDUCED; HEART SEPTAL DEFECTS; HUMANS; INFANT; LACTATES; MAGNESIUM; MALE; MYOCARDIAL ISCHEMIA; MYOCARDIUM; OXYGEN; POTASSIUM CHLORIDE; POTASSIUM COMPOUNDS; PROSPECTIVE STUDIES; SODIUM CHLORIDE; SURGICAL PROCEDURES, ELECTIVE;

EID: 33745187785     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.athoracsur.2006.01.093     Document Type: Article

References (17)

1. Modi P., Suleiman M.-S., Reeves B., et al. Myocardial metabolic changes during pediatric cardiac surgery. a randomized study of 3 cardioplegic techniques. J Thorac Cardiovasc Surg 128 (2004) 67-75
2. Caputo M., Modi P., Imura H., et al. Cold blood versus cold crystalloid cardioplegia for repair of ventricular septal defects in pediatric heart surgery. a randomized controlled trial. Ann Thorac Surg 74 (2002) 530-535
3. Young J.N., Choy I.O., Silva N.K., Obayashi D.Y., and Barkan H.E. Antegrade cold blood cardioplegia is not demonstrably advantageous over cold crystalloid cardioplegia in surgery for congenital heart disease. J Thorac Cardiovasc Surg 114 (1997) 1002-1009
4. Åmark K., Berggren H., Björk K., et al. Blood cardioplegia provides superior protection in infant cardiac surgery. Ann Thorac Surg 80 (2005) 989-994
5. Pietersen H.G., Langenberg C.J., Geskes G., et al. Myocardial substrate uptake and oxidation during and after routine cardiac surgery. J Thorac Cardiovasc Surg 118 (1999) 71-80
6. Svedjeholm R., Svensson S., Ekroth R., et al. Trauma metabolism and the heart. studies of heart and leg amino acid flux after cardiac surgery. Thorac Cardiovasc Surg 38 (1990) 1-5
7. Svensson S., Svedjeholm R., Ekroth R., et al. Trauma metabolism and the heart. Uptake of substrates and effects of insulin early after cardiac operations. J Thorac Cardiovasc Surg 99 (1990) 1063-1073
8. Teoh K.H., Mickle D.A., Weisel R.D., et al. Decreased postoperative myocardial fatty acid oxidation. J Surg Res 44 (1988) 36-44
9. Myrelid Å., Gustafsson J., Ollars B., and Annerén G. Growth charts for Down's syndrome from birth to 18 years of age. Arch Dis Child 87 (2002) 97-103
10. Albertsson Wikland K., Luo Z.C., Niklasson A., and Karlberg J. Swedish population-based longitudinal reference values from birth to 18 years of age for height, weight and head circumference. Acta Paediatr 91 (2002) 739-754
11. Vik-Mo H., and Mjos O.D. Influence of free fatty acids on myocardial oxygen consumption and ischemic injury. Am J Cardiol 48 (1981) 361-365
12. Mudge Jr. G.H., Mills Jr. R.M., Taegtmeyer H., Gorlin R., and Lesch M. Alterations of myocardial amino acid metabolism in chronic ischemic heart disease. J Clin Invest 58 (1976) 1185-1192
13. Thomassen A., Nielsen T.T., Bagger J.P., and Thuesen L. Myocardial glutamate and alanine exchanges related to carbohydrate metabolism in patients with normal and stenotic coronary arteries. Clin Physiol 4 (1984) 425-434
14. Kjellman U., Bjork K., Ekroth R., et al. Alpha-ketoglutarate for myocardial protection in heart surgery. Lancet 345 (1995) 552-553
15. Svedjeholm R., Vanhanen I., Hakanson E., et al. Metabolic and hemodynamic effects of intravenous glutamate infusion early after coronary operations. J Thorac Cardiovasc Surg 112 (1996) 1468-1477
16. Spitzer J.J., and Spitzer J.A. Myocardial metabolism in dogs during hemorrhagic shock. Am J Physiol 222 (1972) 101-105
17. Dhainaut J.F., Huyghebaert M.F., Monsallier J.F., et al. Coronary hemodynamics and myocardial metabolism of lactate, free fatty acids, glucose, and ketones in patients with septic shock. Circulation 75 (1987) 533-541