Clinical Presentation, Temporal Relationship, and Outcome in Thirty-Three Patients With Type 2 Heparin-Induced Thrombocytopenia After Cardiotomy

Annals of Thoracic Surgery

Volumn 82, Issue 1, 2006, Pages 21-26

  Wan, Calvin ^a   Warner, Margaret ^a   De Varennes, Benoit ^a   Ergina, Patrick ^a   Cecere, Renzo ^a   Lachapelle, Kevin ^a  

^a MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DANAPAROID; HEPARIN; THROMBOCYTE FACTOR 4;

ADULT; AGED; ARTICLE; CARDIOTOMY; CLINICAL ARTICLE; CLINICAL FEATURE; COHORT ANALYSIS; DEVICE; DRUG WITHDRAWAL; EMERGENCY SURGERY; FEMALE; HEART FUNCTION; HEART SURGERY; HEPARIN INDUCED THROMBOCYTOPENIA TYPE 2; HUMAN; IMPLANTATION; MALE; MORTALITY; POSTOPERATIVE PERIOD; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; THROMBOCYTE COUNT; THROMBOCYTOPENIA; THROMBOSIS; TREATMENT OUTCOME; UNIVARIATE ANALYSIS;

AGED; AGED, 80 AND OVER; ANTICOAGULANTS; AUTOANTIBODIES; CARDIAC SURGICAL PROCEDURES; CHONDROITIN SULFATES; COHORT STUDIES; DERMATAN SULFATE; DIABETES COMPLICATIONS; FEMALE; GANGRENE; HEPARIN; HEPARITIN SULFATE; HOSPITAL MORTALITY; HUMANS; ISCHEMIA; MALE; MIDDLE AGED; PLATELET FACTOR 4; POSTOPERATIVE COMPLICATIONS; POSTOPERATIVE PERIOD; RETROSPECTIVE STUDIES; RISK FACTORS; THROMBOCYTOPENIA; THROMBOSIS; TIME FACTORS; TREATMENT OUTCOME;

EID: 33745187340     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.athoracsur.2005.12.063     Document Type: Article

References (11)

1. Warkentin T.E. Heparin-induced thrombocytopenia. pathogenesis and management. Br J Haematol 121 (2003) 535-555
2. Follis F., and Schmidt C.A. Cardiopulmonary bypass in patients with heparin-induced thrombocytopenia and thrombosis. Ann Thorac Surg 70 (2000) 2173-2181
3. Walls J.T., Curtis J.J., Silver D., Boley T.M., Schmaltz R.A., and Nawarawong W. Heparin-induced thrombocytopenia in open heart surgical patients. sequelae of late recognition. Ann Thorac Surg 53 (1992) 787-791
4. Singer R.L., Mannion J.D., Bauer T.L., Armenti F.R., and Edie R.N. Complications from heparin-induced thrombocytopenia in patients undergoing cardiopulmonary bypass. Chest 104 (1993) 1436-1440
5. Warkentin T.E., and Greinacher A. Heparin-induced thrombocytopenia and cardiac surgery. Ann Thorac Surg 76 (2003) 638-648
6. Lubenow N., Kempf R., Eichner A., Eicher P., Carlsson L.E., and Greinacher A. Heparin-induced thrombocytopenia. temporal pattern of thrombocytopenia in relation to initial use or reexposure to heparin. Chest 122 (2002) 37-42
7. Bauer T.L., Arepally G., Konkle B.A., et al. Prevalence of heparin-associated antibodies without thrombosis in patients undergoing cardiopulmonary bypass surgery. Circulation 95 (1997) 1242-1246
8. Visentin G.P., Malik M.I., Cyganiak K.A., and Aster R.H. Patients treated with unfractionated heparin during open heart surgery are at high risk to form antibodies reactive with heparin:platelet factor 4 complexes. J Lab Clin Med 128 (1996) 376-383
9. Trossaert M., Gaillard A., Commin P.L., Amiral J., Vissac A., and Fressinaud E. High incidence of anti-heparin/platelet factor 4 antibodies after cardiopulmonary bypass surgery. Br J Haematol 101 (1998) 653-655
10. Pouplard C., May M.A., Iochmann S., et al. Antibodies to platelet factor 4-heparin after cardiopulmonary bypass in patients anticoagulated with unfractionated heparin or a low-molecular-weight heparin. Circulation 99 (1999) 2530-2536
11. Warkentin T.E., and Kelton J.G. A 14-year study of heparin-induced thrombocytopenia. Am J Med 101 (1996) 502-507