An investigation on the antimicrobial activity of Andrographis paniculata extracts and andrographolide in vitro

Asian Journal of Plant Sciences

Volumn 5, Issue 3, 2006, Pages 527-530

  Xu, Youhong ^a   Marshall, Raymond L ^a   Mukkur, Trilochan K S ^a  

^a UNIVERSITY OF SOUTHERN QUEENSLAND   (Australia)

Author keywords

Andrographis paniculata; Andrographolide; Antimicrobial; Disc diffusion; Medicinal plant extracts

Indexed keywords

ANDROGRAPHIS PANICULATA; BACTERIA (MICROORGANISMS); BORDETELLA PERTUSSIS; ESCHERICHIA COLI; LEGIONELLA PNEUMOPHILA; PSEUDOMONAS AERUGINOSA; SALMONELLA TYPHIMURIUM; SHIGELLA SONNEI; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE; STREPTOCOCCUS PYOGENES;

EID: 33745157866     PISSN: 16823974     EISSN: 18125697     Source Type: Journal    
DOI: 10.3923/ajps.2006.527.530     Document Type: Article

References (18)

1. Chang, H.M. and P.P.H. But et al., 1986. Pharmacology and applications of Chinese materia medica. Singapore, World Scientific, 1: 918-928.
2. Chturvedi, G., G.S. Tomar, S.K. Tiwart and K.P. Singh, 1983. Clinical studies on Kalmegh (Andrographis paniculata Nees) in infective hepatitis. J. Internat. Inst. Ayurveda, 2: 208-211.
3. Coon, J.T. and E. Ernst, 2004. Andrographis paniculata in the treatment of upper respiratory tract infections: A systematic review of safety and efficacy. Planta Med., 70: 293-298.
4. Cowan, M.M., 1999. Plant products as antimicrobial agents. Clin. Microbiol. Rev., 12: 564-582.
5. Dulger, B. and A. Gonuz, 2004. Antimicrobial activity of certain plants used in Turkish traditional medicine. Asian J. Plant Sci., 3:104-107.
6. George, M. and K.M. Pandalai, 1949. Investigations on plant antibiotics. Part IV. Further search for antibiotic substances in Indian medicinal plants. Indian J. Med. Res., 37: 169-181.
7. Gupta, S., M.A. Choudhry and J.N.S. Yadava et al., 1990. Antidiarrioeal activity of diterpenes of Andrographis paniculata (Kal-Megh) agent Escherichia coli enterotoxin in vivo models. Intl. J. Crude Drug Res., 284: 273-283.
8. Hancke, J., R.A. Burgos and D.D. Caceres, 1995. A double-blind study with a new monodrug kan jang: Decrease of symptoms and improvement in the recovery from common colds. Phytother. Res., 9: 559-562.
9. Leelarasamee, A., S. Trakulsomboon and N. Sittisomwong, 1990. Undetectable anti-bacterial activity of Andrographis paniculata (Burma) wall. Exness. J. Med. Assoc. Thai, 73: 299-304.
10. Melchior, J., S. Palm and G. Wikman, 1997. Controlled clinical study of standardized Andrographis paniculata extract in common cold-a pilot trial. Phytomedicine, 3: 315-318.
11. Melchior, J., A.A. Spasov, O.V. Ostrovskij, A.E. Bulanov and G. Wikman, 2004. Double-blind, placebo-controlled pilot and phase III study of activity of standardized Andrographis paniculata Herba Nees extract fixed combination (Kan jang) in the treatment of uncomplicated upper-respiratory tract infection. Phytomedicine, 7: 341-350.
12. Mills, S. and K. Bone, 2000. Principles and Practice of Phytotherapy. Edinburgh: Churchill Livingstone, pp: 262-268.
13. Nakanishi, K. et al., 1965. Phytochemical surveyof Malaysian plants: Preliminary chemical and pharmacological screening. Chem. Pharmaceut. Bull., 13: 882-890.
14. Poolsup, N., C. Suthisisang, S. Prathanturarug, A. Asawamekin and U. Chanchareon, 2004. Andrographis paniculata in the symptomatic treatment of uncomplicated upper-respiratory tract infection: Systematic review of randomized controlled trials. J. Clin. Pharm. Ther., 29: 37-45.
15. Prajjal, K., S. Roy and S. Dey, 2003. Antimicrobial activity of Andrographis paniculata. Fitoterapia, 74: 692-694.
16. Puri, A., R. Saxena, R.P. Saxena and K.C. Saxena, 1993. Immunostimulant agents from Andrographis paniculata. J. Natl. Prod., 56: 995-999.
17. Thamlikitkui, V., T. Dechatiwongse and S. Theerapong, 1991. Efficacy of Andrographis paniculata Nees for pharyngotonsillitis in adults. J. Med. Assoc. Thailand, 74: 437-442.
18. Yin, J. and L. Guo, 1993. Contemporary traditional Chinese medicine. Beijing: Xie Yuan.