Biological evaluation, chelation, and molecular modeling studies of novel metal-chelating inhibitors of NF-κB-DNA binding: Structure activity relationships

Journal of Medicinal Chemistry

Volumn 49, Issue 12, 2006, Pages 3595-3601

  Sharma, Rakesh K ^a   Chopra, Shilpa ^a   Sharma, Som D ^a   Pande, Vineet ^b   Ramos, Maria J ^b   Meguro, Kazuyuki ^c   Inoue, Jun Ichiro ^c   Otsuka, Masami ^d  

^a UNIVERSITY OF DELHI   (India)

^b UNIVERSITY OF PORTO   (Portugal)

^c UNIVERSITY OF TOKYO   (Japan)

^d KUMAMOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; AURINTRICARBOXYLIC ACID; BROMOPYROGALLOL RED; CATECHOL DERIVATIVE; CHROMIUM; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN P50; PYROGALLOL; SUPEROXIDE; UNCLASSIFIED DRUG; ZINC;

ANTIOXIDANT ACTIVITY; ARTICLE; CHELATION; COMPLEX FORMATION; DNA BINDING; ELECTRIC POTENTIAL; ELECTROPHORETIC MOBILITY; HYDROGEN BOND; MOLECULAR INTERACTION; MOLECULAR MODEL; MOLECULAR STABILITY; STRUCTURE ACTIVITY RELATION;

ANTIVIRAL AGENTS; AURINTRICARBOXYLIC ACID; CHELATING AGENTS; DNA; ELECTRICITY; ELECTROPHORETIC MOBILITY SHIFT ASSAY; HYDROGEN BONDING; MODELS, MOLECULAR; NF-KAPPA B; NF-KAPPA B P50 SUBUNIT; ORGANOMETALLIC COMPOUNDS; PROTEIN BINDING; PYROGALLOL; STRUCTURE-ACTIVITY RELATIONSHIP; ZINC;

EID: 33745145464     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm050617x     Document Type: Article

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