Crystallographic studies on N-azidoacetyl-β-d-glucopyranosylamine, an inhibitor of glycogen phosphorylase: Comparison with N-acetyl-β-d-glucopyranosylamine

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 15, 2006, Pages 5316-5324

  Petsalakis, Evangelia I ^a   Chrysina, Evangelia D ^a   Tiraidis, Costas ^a   Hadjiloi, Theodoros ^a   Leonidas, Demetres D ^a   Oikonomakos, Nikos G ^a   Aich, Udayanath ^b   Varghese, Babu ^b   Loganathan, Duraikkannu ^b  

^a INSTITUTE OF BIOLOGY   (Greece)

^b INDIAN INSTITUTE OF TECHNOLOGY MADRAS   (India)

Author keywords

Glycogen phosphorylase; Inhibition; N Azidoacetyl d glucopyranosylamine; Type 2 diabetes; X ray crystallography

Indexed keywords

AMINE; AZIDE; GLUCOSE DERIVATIVE; GLYCOGEN PHOSPHORYLASE; N ACETYL BETA GLUCOPYRANOSYLAMINE; N AZIDOACETYL BETA GLUCOPYRANOSYLAMINE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CRYSTALLOGRAPHY; DRUG MECHANISM; GLYCOGEN SYNTHESIS; HYDROGEN BOND; WATER STRUCTURE;

AZIDES; CARBOHYDRATE CONFORMATION; CRYSTALLOGRAPHY, X-RAY; GLUCOSAMINE; GLYCOGEN PHOSPHORYLASE; HYDROGEN BONDING; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33745125092     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.03.044     Document Type: Article

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