Screening of antibiotic residues in ewes' milk destined to cheese by a commercial microbiological inhibition assay

Food Additives and Contaminants

Volumn 23, Issue 7, 2006, Pages 660-667

  Yamaki, M ^a   Berruga, Maria Isabel ^a   Althaus, R L ^b   Molina, M P ^c   Molina, A ^a  

^a UNIVERSITY OF CASTILLA LA MANCHA   (Spain)

^b UNIVERSIDAD NACIONAL DEL LITORAL   (Argentina)

^c UNIVERSITAT POLITÈCNICA DE VALÈNCIA   (Spain)

Author keywords

Antibiotic residue; Eclipse '100ov' ; Ewes' milk quality; Screening test

Indexed keywords

ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; BETA LACTAM; DRUG RESIDUE; LIPID; PENICILLINASE;

ANALYTICAL EQUIPMENT; ARTICLE; BACTERIOLOGY; CELL COUNT; CHEESE; COMMERCIAL PHENOMENA; CONTROLLED STUDY; DAIRYING; FALSE POSITIVE RESULT; FEMALE; FOOD ANALYSIS; FOOD COMPOSITION; FOOD INDUSTRY; HEAT TREATMENT; INTERMETHOD COMPARISON; LIPID COMPOSITION; MICROBIOLOGICAL EXAMINATION; MILK; NONHUMAN; PRIORITY JOURNAL; PROBABILITY; PROTEIN ANALYSIS; QUANTITATIVE ANALYSIS; REDUCTION; RESIDUE ANALYSIS; SAMPLE SIZE; SCREENING TEST; SOMATIC CELL; SPAIN; TEMPERATURE MEASUREMENT;

ANIMALS; ANTI-BACTERIAL AGENTS; CHEESE; DRUG RESIDUES; FEMALE; FOOD ANALYSIS; FOOD CONTAMINATION; MICROBIAL SENSITIVITY TESTS; MILK; SEASONS; SHEEP;

OVIS;

EID: 33745100224     PISSN: 0265203X     EISSN: 14645122     Source Type: Journal    
DOI: 10.1080/02652030500428655     Document Type: Article

References (31)

1. Althaus, RL and Torres, A and Peris, C and Beltrán, MC and Fernández, N and Molina, P. (2003) Accuracy of BRT and Delvotest microbial inhibition tests by composition of ewes' milk Journal of Food Protection, 66, pp. 473-478.
2. Andrew, SM and Frobish, RA and Paape, MJ and Maturin, LJ. (1997) Evaluation of selected antibiotic residue screening tests for milk from individual cows and examination of factors that affect the probability of false-positive outcomes Journal of Dairy Science, 80, pp. 3050-3057.
3. Association of Official Analytical Chemists. Antibiotic and veterinary drug residues test kits. 2004. (available at:) (accessed on 25 November 2004)
4. Barbosa, M and Suhren, G and Beukers, R. (2004) Suitability and application of available test kits for the detection of residues of antimicrobials in milk from species other than the cow - a review. IDF Bulletin no. 390
5. Bergonier, D and Berthelot, X. (2003) New advances in epizootiology and control of ewe mastitis Livestock Production Science, 79, pp. 1-16.
6. Carlsson, A and Bjorck, L and Persson, K. (1989) Lactoferrin and lysozyme in milk during acute mastitis and their inhibitory effect in Delvotest P Journal of Dairy Science, 72, pp. 3166-3175.
7. Continanza, RM and Tiburtini, S and Paggi, U. (2003) Determinazione di inibenti nel latte mediante kit microbiologico Il Latte, 28, pp. 80-84.
8. EC. (1992) Council Directive (EC) 92/46 of 16 June 1992 laying down the health rules for the production and placing on the market of raw milk, heat-treated milk and milk-based products Official Journal of the European Communities, L 268, pp. 18-24.
9. EC. (1996) Council Directive (EC) 96/23 of 29 April 1996 on measures to monitor certain substances and residues thereof in live animals and animal products and repealing Directives 85/358/EEC and 86/469/EEC and Decisions 89/187/EEC and 91/664/EEC Official Journal of the European Communities, L 125, pp. 10-32.
10. EC. (1997) Commission Decision (EC) No 97/747 of 27 October 1997 fixing the levels and frequencies of sampling provided for by Council Directive 96/23/EC for the monitoring of certain substances and residues thereof in certain animal products Official Journal of the European Communities, L 303, pp. 12-15.
11. Esnal, A and Gamallo, JA and Marco, JC and Rodríguez, L and Sopena, J and Martinez, F and Del Real, MA and García, I and Ordóñez, J and Martín, S and Extramiana, AB.(2002) Valoración práctica de un estudio de inhibidores y de recuento de patógenos contagiosos en leche de tanque de cuatro agrupaciones de productores de leche de oveja. In Proceedings of the VI Jornadas Internacionales de la Sociedad Española de Ovinotecnia y Caprinotecnia. (pp. 576-582). Valencia: SEOC. 19-21 September, Valencia, Spain
12. FAOSTAT. Datos Agrícolas de FAOSTAT. 2004. (available at:) (accessed on 10 December 2004)
13. Food and Drug Administration/Center for Food Safety and Applied Nutrition. National milk drug residue data base fiscal year 2000 annual report. 2001. (available at:) (accessed on 4 May 2004)
14. Gallego, R. Análisis de estructuras y sistemas de producción en el sector del ganado ovino Manchego. 2002. (available at:) (accessed 12 January 2005)
15. Gonzalo, C and Carriedo, JA and Baro, A and Primitivo, FS. (1994) Factors influencing variation of test day milk yield, somatic cell count, fat, and protein in dairy sheep Journal of Dairy Science, 77, pp. 1537-1542.
16. Herrera, E and Abecia, JA and Martín, S. (2004) Antibióticos en leche de tanque Albéitar, 75, pp. 54-55.
17. Kang, J-H and Kondo, F. (2001) Occurrence of false-positive results of inhibitor on milk samples using the Delvotest SP assay Journal of Food Protection, 64, pp. 1211-1215.
18. Ministerio de Agricultura, Pesca y Alimentación. Anuario de estadística agroalimentaria. 2002a. (available at:) (accessed on 11 March 2004)
19. Ministerio de Agricultura, Pesca y Alimentacín. Datos de las Denominaciones de Origen Protegidas (D. O. P.) e Indicaciones Geográficas Protegidas (I. G. P.) de productos agroalimentarios. 2002b. (available at:) (accessed on 11 March 2004)
20. (1999) The effect of processing on veterinary residues in foods. In Impact of processing on food safety. New York, NY: Kluwer. p. 233
21. Molina, MP and Althaus, RL and Molina, A and Fernández, N. (2003a) Antimicrobial agent detection in ewes' milk by the microbial inhibitor test brilliant black reduction test - BRT AiM International Dairy Journal, 13, pp. 821-826.
22. Molina, MP and Althaus, RL and Balasch, S and Torres, A and Peris, C and Fernández, N. (2003b) Evaluation of screening test for detection of antimicrobial residues in ewes' milk Journal of Dairy Science, 86, pp. 1947-1952.
23. Pérez-Guzmán, MD and Oliver, F and Gallego, R and García, M and Montoro, V. (2000) Recuentos de células somáticas en leche de tanque de ganaderías de raza ovina Manchega durante los años 1992-1999 ILE, May, pp. 32-34.
24. Sischo, WM and Burns, CM. (1993) Field trial of four cowside antibiotic screening test Journal of the American Veterinary Medical Association, 202, pp. 1249-1254.
25. Statgraphics.(1997) Statgraphics Plus. Rockville MD: Manugistics, Inc. version 5.1, user manual
26. Suhren, G and Reichmuth, J. (2003) Messbarkeit und Entwicklung der hygienischen Wertigkeit des Rohstofs Milch Kieler Milchwirtschaftliche Forschungsberichte, 55, pp. 5-36.
27. Suhren, G and Reichmuth, J and Walte, HG. (1996) Detection of β-lactam antibiotics in milk by the Penzym-test Milchwissenschaft, 51, pp. 269-273.
28. Van Eenennaam, AL and Cullor, JS and Perani, L and Gardner, IA and Smith, WL and Dellinger, J and Guterbock, WM. (1993) Evaluation of milk antibiotic residue screening tests in cattle with naturally occurring clinical mastitis Journal of Dairy Science, 76, pp. 3041-3053.
29. Wolfson, LM and Summer, SS. (1993) Antibacterial activity of the lactoperoxidase system: A review Journal of Food Protection, 56, pp. 887-892.
30. Yamaki, M and Berruga, MI and Althaus, RL and Molina, MP and Molina, A. (2004) Occurrence of antibiotic residues in milk from Manchega ewe dairy farms Journal of Dairy Science, 87, pp. 3132-3137.
31. Zorraquino, MA. (2005) Inactivación térmica de sustancias antimicrobianas en la leche. In. Universidad Publica de Navarra.