-
1
-
-
0027370108
-
The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
-
The Diabetes Control and Complications Trial Research Group
-
The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 1993; 329:977-986.
-
(1993)
N Engl J Med
, vol.329
, pp. 977-986
-
-
-
2
-
-
0032511583
-
Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
-
UK Prospective Diabetes Study (UKPDS) Group
-
UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998; 352:837-853.
-
(1998)
Lancet
, vol.352
, pp. 837-853
-
-
-
3
-
-
2342652451
-
A systematic review of adherence with medications for diabetes
-
Cramer JA. A systematic review of adherence with medications for diabetes. Diabetes Care 2004; 27:1218-1224.
-
(2004)
Diabetes Care
, vol.27
, pp. 1218-1224
-
-
Cramer, J.A.1
-
4
-
-
0032802167
-
Ten-year follow-up of antidiabetic drug use, nonadherence, and mortality in a defined population with type 2 diabetes mellitus
-
Brown JB, Nicholas GA, Glauber HS, Bakst A. Ten-year follow-up of antidiabetic drug use, nonadherence, and mortality in a defined population with type 2 diabetes mellitus. Clin Ther 1999; 21:1045-1057.
-
(1999)
Clin Ther
, vol.21
, pp. 1045-1057
-
-
Brown, J.B.1
Nicholas, G.A.2
Glauber, H.S.3
Bakst, A.4
-
5
-
-
0015107117
-
Insulin across respiratory mucosae by aerosol delivery
-
Wigley F, Londono JH, Wood SH, Shipp JC, Waldman RH. Insulin across respiratory mucosae by aerosol delivery. Diabetes 1971; 20:552-556.
-
(1971)
Diabetes
, vol.20
, pp. 552-556
-
-
Wigley, F.1
Londono, J.H.2
Wood, S.H.3
Shipp, J.C.4
Waldman, R.H.5
-
6
-
-
0027506440
-
Preliminary study of the efficacy of insulin aerosol delivered by oral inhalation in diabetic patients
-
Laube B, Georgopoulos A, Adams GI. Preliminary study of the efficacy of insulin aerosol delivered by oral inhalation in diabetic patients. JAMA 1993; 269:2106-2109.
-
(1993)
JAMA
, vol.269
, pp. 2106-2109
-
-
Laube, B.1
Georgopoulos, A.2
Adams, G.I.3
-
7
-
-
0032240027
-
The lung as an alternative route of delivery for insulin in controlling postprandial glucose levels in patients with diabetes
-
Laube B, Benedict G, Dobs A. The lung as an alternative route of delivery for insulin in controlling postprandial glucose levels in patients with diabetes. Chest 1998; 114:1734-1739.
-
(1998)
Chest
, vol.114
, pp. 1734-1739
-
-
Laube, B.1
Benedict, G.2
Dobs, A.3
-
8
-
-
0035719828
-
The lung as a route for systemic delivery of therapeutic proteins and peptides
-
Agu RU, Ugwoke MI, Armand M, Kinget R, Verbeke N. The lung as a route for systemic delivery of therapeutic proteins and peptides. Respir Res 2001; 2:198-209.
-
(2001)
Respir Res
, vol.2
, pp. 198-209
-
-
Agu, R.U.1
Ugwoke, M.I.2
Armand, M.3
Kinget, R.4
Verbeke, N.5
-
9
-
-
0033576322
-
Tennis anyone? The lungs as a new court for systemic therapy
-
Newhouse M. Tennis anyone? The lungs as a new court for systemic therapy. CMAJ 1999; 161:1287-1288.
-
(1999)
CMAJ
, vol.161
, pp. 1287-1288
-
-
Newhouse, M.1
-
10
-
-
10744227569
-
Large porous particles for pulmonary drug delivery
-
Edwards D, Hanes J, Caponetti G, et al. Large porous particles for pulmonary drug delivery. Science 1997; 276:1868-1872.
-
(1997)
Science
, vol.276
, pp. 1868-1872
-
-
Edwards, D.1
Hanes, J.2
Caponetti, G.3
-
11
-
-
10744228212
-
Dose-response relationships of inhaled insulin delivered via the Aeroclose insulin inhaler and subcutaneously injected insulin in patients with type 2 diabetes
-
Kim D, Mudaliar S, Chinnapongse S, et al. Dose-response relationships of inhaled insulin delivered via the Aeroclose insulin inhaler and subcutaneously injected insulin in patients with type 2 diabetes. Diabetes Care 2003; 26:2842-2847.
-
(2003)
Diabetes Care
, vol.26
, pp. 2842-2847
-
-
Kim, D.1
Mudaliar, S.2
Chinnapongse, S.3
-
12
-
-
0141562799
-
Absorption and metabolic effect of inhaled insulin: Intrapatient variability after inhalation via the Aeroclose insulin inhaler in patients with type 2 diabetes
-
Perera AD, Kapitza C, Nosek L, et al. Absorption and metabolic effect of inhaled insulin: intrapatient variability after inhalation via the Aeroclose insulin inhaler in patients with type 2 diabetes. Diabetes Care 2002; 25:2276-2281.
-
(2002)
Diabetes Care
, vol.25
, pp. 2276-2281
-
-
Perera, A.D.1
Kapitza, C.2
Nosek, L.3
-
13
-
-
3142702338
-
Inhaled micronized crystalline human insulin using a dry powder inhaler: Dose-response and time-action profiles
-
Rave K, Nosek L, Heinemann L, et al. Inhaled micronized crystalline human insulin using a dry powder inhaler: dose-response and time-action profiles. Diabet Med 2004; 21:763-768.
-
(2004)
Diabet Med
, vol.21
, pp. 763-768
-
-
Rave, K.1
Nosek, L.2
Heinemann, L.3
-
14
-
-
25644437167
-
Dose response of inhaled dry-powder insulin and dose equivalence to subcutaneous insulin lispro
-
Rave KM, Nosek L, de la Pena A, et al. Dose response of inhaled dry-powder insulin and dose equivalence to subcutaneous insulin lispro. Diabetes Care 2005; 28:2400-2405.
-
(2005)
Diabetes Care
, vol.28
, pp. 2400-2405
-
-
Rave, K.M.1
Nosek, L.2
de la Pena, A.3
-
15
-
-
0030614874
-
Time-action profile of inhaled insulin
-
Heinemann L, Traut T, Heise T. Time-action profile of inhaled insulin. Diabet Med 1997; 14:63-72.
-
(1997)
Diabet Med
, vol.14
, pp. 63-72
-
-
Heinemann, L.1
Traut, T.2
Heise, T.3
-
16
-
-
4644372272
-
Efficacy and safety of inhaled insulin (Exubera) compared with subcutaneous insulin therapy in patients with type 2 diabetes: Results of a 6-month, randomized, comparative trial
-
Hollander PA, Blonde L, Rowe R, et al. Efficacy and safety of inhaled insulin (Exubera) compared with subcutaneous insulin therapy in patients with type 2 diabetes: results of a 6-month, randomized, comparative trial. Diabetes Care 2004; 27:2356-2362.
-
(2004)
Diabetes Care
, vol.27
, pp. 2356-2362
-
-
Hollander, P.A.1
Blonde, L.2
Rowe, R.3
-
17
-
-
4344652690
-
Intrasubject variability of inhaled insulin in type 1 diabetes: A comparison with subcutaneous insulin
-
Kapitza C, Hompesch M, Scharling B, Heise T. Intrasubject variability of inhaled insulin in type 1 diabetes: a comparison with subcutaneous insulin. Diabetes Technol Ther 2004; 6:466-472.
-
(2004)
Diabetes Technol Ther
, vol.6
, pp. 466-472
-
-
Kapitza, C.1
Hompesch, M.2
Scharling, B.3
Heise, T.4
-
18
-
-
0036007839
-
Technosphere/Insulin - Proof of concept study with a new insulin formulation for pulmonary delivery
-
Steiner S, Pfutzner A, Wilson BR, Harzer O, Heinemann L, Rave K. Technosphere/Insulin - proof of concept study with a new insulin formulation for pulmonary delivery. Exp Clin Endocrinol Diabetes 2002; 110:17-21.
-
(2002)
Exp Clin Endocrinol Diabetes
, vol.110
, pp. 17-21
-
-
Steiner, S.1
Pfutzner, A.2
Wilson, B.R.3
Harzer, O.4
Heinemann, L.5
Rave, K.6
-
19
-
-
18144368866
-
Time-action profile of inhaled insulin in comparison with subcutaneously injected insulin lispro and regular human insulin
-
Rave K, Bott S, Heinemann L, et al. Time-action profile of inhaled insulin in comparison with subcutaneously injected insulin lispro and regular human insulin. Diabetes Care 2005; 28:1077-1082.
-
(2005)
Diabetes Care
, vol.28
, pp. 1077-1082
-
-
Rave, K.1
Bott, S.2
Heinemann, L.3
-
20
-
-
0029847551
-
Intrapulmonary administration of insulin to healthy volunteers
-
Jendle J, Karlberg B. Intrapulmonary administration of insulin to healthy volunteers. J Intern Med 1996; 240:93-98.
-
(1996)
J Intern Med
, vol.240
, pp. 93-98
-
-
Jendle, J.1
Karlberg, B.2
-
21
-
-
0033851983
-
Intra-individual variability of the metabolic effect of inhaled insulin together with an absorption enhancer
-
Heinemann L, Klappoth W, Rave K, Hompesch B, Linkeschowa R, Heise T. Intra-individual variability of the metabolic effect of inhaled insulin together with an absorption enhancer. Diabetes Care 2000; 23:1343-1347.
-
(2000)
Diabetes Care
, vol.23
, pp. 1343-1347
-
-
Heinemann, L.1
Klappoth, W.2
Rave, K.3
Hompesch, B.4
Linkeschowa, R.5
Heise, T.6
-
22
-
-
33745064779
-
-
Pfizer. Insulin Exubera US Package Insert
-
Pfizer. Insulin Exubera US Package Insert, 2006.
-
(2006)
-
-
-
23
-
-
7444270287
-
Efficacy and safety of inhaled insulin (Exubera) compared with subcutaneous insulin therapy in patients with type 1 diabetes: Results of a 6-month, randomized, comparative trial
-
Exubera Phase III Study Group. al
-
Quattrin T, Belanger A, Bohannon NJ, Schwartz SL; Exubera Phase III Study Group. al. Efficacy and safety of inhaled insulin (Exubera) compared with subcutaneous insulin therapy in patients with type 1 diabetes: results of a 6-month, randomized, comparative trial. Diabetes Care 2004; 27:2622-2627.
-
(2004)
Diabetes Care
, vol.27
, pp. 2622-2627
-
-
Quattrin, T.1
Belanger, A.2
Bohannon, N.J.3
Schwartz, S.L.4
-
24
-
-
21544464003
-
Use of inhaled insulin in a basal/bolus insulin regimen in type 1 diabetic subjects: A 6-month, randomized, comparative trial
-
Inhaled Insulin Phase III Type 1 Diabetes Study Group
-
Skyler JS, Weinstock RS, Raskin P, et al; Inhaled Insulin Phase III Type 1 Diabetes Study Group. Use of inhaled insulin in a basal/bolus insulin regimen in type 1 diabetic subjects: a 6-month, randomized, comparative trial. Diabetes Care 2005; 28:1630-1635.
-
(2005)
Diabetes Care
, vol.28
, pp. 1630-1635
-
-
Skyler, J.S.1
Weinstock, R.S.2
Raskin, P.3
-
25
-
-
0035814836
-
Inhaled human insulin treatment in patients with type 2 diabetes mellitus
-
Inhaled Insulin Study Group
-
Cefalu WT, Skyler JS, Kourides IA, et al; Inhaled Insulin Study Group. Inhaled human insulin treatment in patients with type 2 diabetes mellitus. Ann Intern Med 2001; 134:203-207.
-
(2001)
Ann Intern Med
, vol.134
, pp. 203-207
-
-
Cefalu, W.T.1
Skyler, J.S.2
Kourides, I.A.3
-
26
-
-
1042303481
-
Intensive therapy with inhaled insulin via the AERx insulin diabetes management system: A 12-week proof-of-concept trial in patients with type 2 diabetes
-
Hermansen K, Ronnemaa T, Petersen AH, Bellaire S, Adamson U. Intensive therapy with inhaled insulin via the AERx insulin diabetes management system: a 12-week proof-of-concept trial in patients with type 2 diabetes. Diabetes Care 2004; 27:162-167.
-
(2004)
Diabetes Care
, vol.27
, pp. 162-167
-
-
Hermansen, K.1
Ronnemaa, T.2
Petersen, A.H.3
Bellaire, S.4
Adamson, U.5
-
27
-
-
26944435504
-
Inhaled insulin improves glycemic control when substituted for or added to oral combination therapy in type 2 diabetes: A randomized, controlled trial
-
Rosenstock J, Zinman B, Murphy LJ, et al. Inhaled insulin improves glycemic control when substituted for or added to oral combination therapy in type 2 diabetes: a randomized, controlled trial. Ann Intern Med 2005; 143:549-558.
-
(2005)
Ann Intern Med
, vol.143
, pp. 549-558
-
-
Rosenstock, J.1
Zinman, B.2
Murphy, L.J.3
-
28
-
-
23044488164
-
Efficacy of inhaled insulin in patients with type 2 diabetes not controlled with diet and exercise: A 12-week, randomized, comparative trial
-
Exubera Phase III Study Group
-
DeFronzo RA, Bergenstal RM, Cefalu WT, et al; Exubera Phase III Study Group. Efficacy of inhaled insulin in patients with type 2 diabetes not controlled with diet and exercise: a 12-week, randomized, comparative trial. Diabetes Care 2005; 28:1922-1928.
-
(2005)
Diabetes Care
, vol.28
, pp. 1922-1928
-
-
DeFronzo, R.A.1
Bergenstal, R.M.2
Cefalu, W.T.3
-
29
-
-
0025282127
-
Aerosols for systemic treatment
-
Kohler D. Aerosols for systemic treatment. Lung 1990; 168(suppl):677-684.
-
(1990)
Lung
, vol.168
, Issue.SUPPL.
, pp. 677-684
-
-
Kohler, D.1
-
30
-
-
0038248882
-
The impact of smoking on inhaled insulin
-
Himmelmann A, Jendle J, Mellen A, Petersen AH, Dahl UL, Wollmer P. The impact of smoking on inhaled insulin. Diabetes Care 2003; 26:677-682.
-
(2003)
Diabetes Care
, vol.26
, pp. 677-682
-
-
Himmelmann, A.1
Jendle, J.2
Mellen, A.3
Petersen, A.H.4
Dahl, U.L.5
Wollmer, P.6
-
31
-
-
22144441074
-
The effect of smoking cessation and subsequent resumption on absorption of inhaled insulin (Exubera)
-
[Abstract]
-
Becker RHA, Sha S, Frick AD, Piechatzek R. The effect of smoking cessation and subsequent resumption on absorption of inhaled insulin (Exubera) [Abstract]. Diabetes 2003; 52:A37.
-
(2003)
Diabetes
, vol.52
-
-
Becker, R.H.A.1
Sha, S.2
Frick, A.D.3
Piechatzek, R.4
-
32
-
-
33745067717
-
-
Department of Health and Human Services Food And Drug Administration Center for Drug Evaluation and Research Endocrinologic and Metabolic Drugs Advisory Committee www.fda.gov/ohrms/dockets/ac/05/transcripts /2005-4169T1.pdf. Transcript of the meeting of Thursday, September 8
-
Department of Health and Human Services Food And Drug Administration Center for Drug Evaluation and Research Endocrinologic and Metabolic Drugs Advisory Committee. www.fda.gov/ohrms/dockets/ac/05/transcripts/ 2005-4169T1.pdf. Transcript of the meeting of Thursday, September 8, 2005.
-
(2005)
-
-
-
33
-
-
0038248885
-
Inhaled insulin using the AERx Insulin Diabetes Management System in healthy and asthmatic subjects
-
Henry RR, Mudaliar SIR, Howland WC 3rd, et al. Inhaled insulin using the AERx Insulin Diabetes Management System in healthy and asthmatic subjects. Diabetes Care 2003; 26:764-769.
-
(2003)
Diabetes Care
, vol.26
, pp. 764-769
-
-
Henry, R.R.1
Mudaliar, S.R.2
Howland III, W.C.3
-
34
-
-
18244365084
-
Influence of acute upper respiratory tract infection on the absorption of inhaled insulin using the AERx Insulin Diabetes Management System
-
McElduff A, Mather LE, Kam PC, Clauson P. Influence of acute upper respiratory tract infection on the absorption of inhaled insulin using the AERx Insulin Diabetes Management System. Br J Clin Pharmacol 2005; 59:546-551.
-
(2005)
Br J Clin Pharmacol
, vol.59
, pp. 546-551
-
-
McElduff, A.1
Mather, L.E.2
Kam, P.C.3
Clauson, P.4
-
36
-
-
0036120714
-
Insulin inhibits apoptosis of macrophage cell line, THP-1 cells, via phosphatidylinositol-3-kinase-dependent pathway
-
lida K, Suzuki H, Sone H, et al. Insulin inhibits apoptosis of macrophage cell line, THP-1 cells, via phosphatidylinositol-3-kinase-dependent pathway. Arterioscler Thromb Vasc Biol 2002; 22:380-386.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 380-386
-
-
Lida, K.1
Suzuki, H.2
Sone, H.3
-
37
-
-
0035798916
-
Efficacy of inhaled human insulin in type 1 diabetes mellitus: A randomised proof-of-concept study
-
Skyler JS, Cefalu WT, Kourides IA, et al. Efficacy of inhaled human insulin in type 1 diabetes mellitus: a randomised proof-of-concept study. Lancet 2001; 357:331-335.
-
(2001)
Lancet
, vol.357
, pp. 331-335
-
-
Skyler, J.S.1
Cefalu, W.T.2
Kourides, I.A.3
-
38
-
-
0142243294
-
Inhaled insulin provides improved glycemic control in patients with type 2 diabetes mellitus inadequately controlled with oral agents: A randomized controlled trial
-
Inhaled Insulin Phase II Study Group
-
Weiss SR, Cheng SL, Kourides IA, Gelfand RA, Landschulz WH; Inhaled Insulin Phase II Study Group. Inhaled insulin provides improved glycemic control in patients with type 2 diabetes mellitus inadequately controlled with oral agents: a randomized controlled trial. Arch Intern Med 2003; 163:2277-2282.
-
(2003)
Arch Intern Med
, vol.163
, pp. 2277-2282
-
-
Weiss, S.R.1
Cheng, S.L.2
Kourides, I.A.3
Gelfand, R.A.4
Landschulz, W.H.5
-
39
-
-
21244462394
-
Antibody response to inhaled insulin in patients with type 1 or type 2 diabetes. An analysis of initial phase II and III inhaled insulin (Exubera) trials and a two-year extension trial
-
Fineberg SE, Kawabata T, Finco-Kent D, Liu C, Krasner A. Antibody response to inhaled insulin in patients with type 1 or type 2 diabetes. An analysis of initial phase II and III inhaled insulin (Exubera) trials and a two-year extension trial. J Clin Endocrinol Metab 2005; 90:3287-3294.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 3287-3294
-
-
Fineberg, S.E.1
Kawabata, T.2
Finco-Kent, D.3
Liu, C.4
Krasner, A.5
-
40
-
-
24144461892
-
The effect of insulin antibodies on the metabolic action of inhaled and subcutaneous insulin: A prospective randomized pharmacodynamic study
-
Heise T, Bott S, Tusek C, et al. The effect of insulin antibodies on the metabolic action of inhaled and subcutaneous insulin: a prospective randomized pharmacodynamic study. Diabetes Care 2005; 28:2161-2169.
-
(2005)
Diabetes Care
, vol.28
, pp. 2161-2169
-
-
Heise, T.1
Bott, S.2
Tusek, C.3
-
41
-
-
0035458867
-
Treatment satisfaction with inhaled insulin in patients with type 1 diabetes: A randomized controlled trial
-
Gerber RA, Cappelleri JC, Kourides IA, Gelfand RA. Treatment satisfaction with inhaled insulin in patients with type 1 diabetes: a randomized controlled trial. Diabetes Care 2001; 24:1556-1559.
-
(2001)
Diabetes Care
, vol.24
, pp. 1556-1559
-
-
Gerber, R.A.1
Cappelleri, J.C.2
Kourides, I.A.3
Gelfand, R.A.4
-
42
-
-
0036245372
-
Treatment satisfaction in type 2 diabetes: A comparison between an inhaled insulin regimen and a subcutaneous insulin regimen
-
Cappelleri JC, Cefalu WT, Rosenstock J, Kourides IA, Gerber RA. Treatment satisfaction in type 2 diabetes: a comparison between an inhaled insulin regimen and a subcutaneous insulin regimen. Clin Ther 2002; 24:552-564.
-
(2002)
Clin Ther
, vol.24
, pp. 552-564
-
-
Cappelleri, J.C.1
Cefalu, W.T.2
Rosenstock, J.3
Kourides, I.A.4
Gerber, R.A.5
-
43
-
-
12344317702
-
Compliance with inhaled insulin treatment using the AERx iDMS Insulin Diabetes Management System
-
Cramer JA, Okikawa J, Bellaire S, Clauson P. Compliance with inhaled insulin treatment using the AERx iDMS Insulin Diabetes Management System. Diabetes Technol Ther 2004; 6:800-807.
-
(2004)
Diabetes Technol Ther
, vol.6
, pp. 800-807
-
-
Cramer, J.A.1
Okikawa, J.2
Bellaire, S.3
Clauson, P.4
-
44
-
-
19944431309
-
Availability of inhaled insulin promotes greater perceived acceptance of insulin therapy in patients with type 2 diabetes
-
Freemantle N, Blonde L, Duhot D, et al. Availability of inhaled insulin promotes greater perceived acceptance of insulin therapy in patients with type 2 diabetes. Diabetes Care 2005; 28:427-428.
-
(2005)
Diabetes Care
, vol.28
, pp. 427-428
-
-
Freemantle, N.1
Blonde, L.2
Duhot, D.3
|