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Volumn 73, Issue 6, 2006, Pages 569-578

Inhaled human insulin: An inspiration for patients with diabetes mellitus?

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HEMOGLOBIN A1C; INSULIN; INSULIN ZINC SUSPENSION; ISOPHANE INSULIN; LONG ACTING INSULIN; ORAL ANTIDIABETIC AGENT; ROSIGLITAZONE;

EID: 33745085530     PISSN: 08911150     EISSN: None     Source Type: Journal    
DOI: 10.3949/ccjm.73.6.569     Document Type: Review
Times cited : (10)

References (44)
  • 1
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • The Diabetes Control and Complications Trial Research Group
    • The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 1993; 329:977-986.
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 2
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
    • UK Prospective Diabetes Study (UKPDS) Group
    • UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998; 352:837-853.
    • (1998) Lancet , vol.352 , pp. 837-853
  • 3
    • 2342652451 scopus 로고    scopus 로고
    • A systematic review of adherence with medications for diabetes
    • Cramer JA. A systematic review of adherence with medications for diabetes. Diabetes Care 2004; 27:1218-1224.
    • (2004) Diabetes Care , vol.27 , pp. 1218-1224
    • Cramer, J.A.1
  • 4
    • 0032802167 scopus 로고    scopus 로고
    • Ten-year follow-up of antidiabetic drug use, nonadherence, and mortality in a defined population with type 2 diabetes mellitus
    • Brown JB, Nicholas GA, Glauber HS, Bakst A. Ten-year follow-up of antidiabetic drug use, nonadherence, and mortality in a defined population with type 2 diabetes mellitus. Clin Ther 1999; 21:1045-1057.
    • (1999) Clin Ther , vol.21 , pp. 1045-1057
    • Brown, J.B.1    Nicholas, G.A.2    Glauber, H.S.3    Bakst, A.4
  • 6
    • 0027506440 scopus 로고
    • Preliminary study of the efficacy of insulin aerosol delivered by oral inhalation in diabetic patients
    • Laube B, Georgopoulos A, Adams GI. Preliminary study of the efficacy of insulin aerosol delivered by oral inhalation in diabetic patients. JAMA 1993; 269:2106-2109.
    • (1993) JAMA , vol.269 , pp. 2106-2109
    • Laube, B.1    Georgopoulos, A.2    Adams, G.I.3
  • 7
    • 0032240027 scopus 로고    scopus 로고
    • The lung as an alternative route of delivery for insulin in controlling postprandial glucose levels in patients with diabetes
    • Laube B, Benedict G, Dobs A. The lung as an alternative route of delivery for insulin in controlling postprandial glucose levels in patients with diabetes. Chest 1998; 114:1734-1739.
    • (1998) Chest , vol.114 , pp. 1734-1739
    • Laube, B.1    Benedict, G.2    Dobs, A.3
  • 8
    • 0035719828 scopus 로고    scopus 로고
    • The lung as a route for systemic delivery of therapeutic proteins and peptides
    • Agu RU, Ugwoke MI, Armand M, Kinget R, Verbeke N. The lung as a route for systemic delivery of therapeutic proteins and peptides. Respir Res 2001; 2:198-209.
    • (2001) Respir Res , vol.2 , pp. 198-209
    • Agu, R.U.1    Ugwoke, M.I.2    Armand, M.3    Kinget, R.4    Verbeke, N.5
  • 9
    • 0033576322 scopus 로고    scopus 로고
    • Tennis anyone? The lungs as a new court for systemic therapy
    • Newhouse M. Tennis anyone? The lungs as a new court for systemic therapy. CMAJ 1999; 161:1287-1288.
    • (1999) CMAJ , vol.161 , pp. 1287-1288
    • Newhouse, M.1
  • 10
    • 10744227569 scopus 로고    scopus 로고
    • Large porous particles for pulmonary drug delivery
    • Edwards D, Hanes J, Caponetti G, et al. Large porous particles for pulmonary drug delivery. Science 1997; 276:1868-1872.
    • (1997) Science , vol.276 , pp. 1868-1872
    • Edwards, D.1    Hanes, J.2    Caponetti, G.3
  • 11
    • 10744228212 scopus 로고    scopus 로고
    • Dose-response relationships of inhaled insulin delivered via the Aeroclose insulin inhaler and subcutaneously injected insulin in patients with type 2 diabetes
    • Kim D, Mudaliar S, Chinnapongse S, et al. Dose-response relationships of inhaled insulin delivered via the Aeroclose insulin inhaler and subcutaneously injected insulin in patients with type 2 diabetes. Diabetes Care 2003; 26:2842-2847.
    • (2003) Diabetes Care , vol.26 , pp. 2842-2847
    • Kim, D.1    Mudaliar, S.2    Chinnapongse, S.3
  • 12
    • 0141562799 scopus 로고    scopus 로고
    • Absorption and metabolic effect of inhaled insulin: Intrapatient variability after inhalation via the Aeroclose insulin inhaler in patients with type 2 diabetes
    • Perera AD, Kapitza C, Nosek L, et al. Absorption and metabolic effect of inhaled insulin: intrapatient variability after inhalation via the Aeroclose insulin inhaler in patients with type 2 diabetes. Diabetes Care 2002; 25:2276-2281.
    • (2002) Diabetes Care , vol.25 , pp. 2276-2281
    • Perera, A.D.1    Kapitza, C.2    Nosek, L.3
  • 13
    • 3142702338 scopus 로고    scopus 로고
    • Inhaled micronized crystalline human insulin using a dry powder inhaler: Dose-response and time-action profiles
    • Rave K, Nosek L, Heinemann L, et al. Inhaled micronized crystalline human insulin using a dry powder inhaler: dose-response and time-action profiles. Diabet Med 2004; 21:763-768.
    • (2004) Diabet Med , vol.21 , pp. 763-768
    • Rave, K.1    Nosek, L.2    Heinemann, L.3
  • 14
    • 25644437167 scopus 로고    scopus 로고
    • Dose response of inhaled dry-powder insulin and dose equivalence to subcutaneous insulin lispro
    • Rave KM, Nosek L, de la Pena A, et al. Dose response of inhaled dry-powder insulin and dose equivalence to subcutaneous insulin lispro. Diabetes Care 2005; 28:2400-2405.
    • (2005) Diabetes Care , vol.28 , pp. 2400-2405
    • Rave, K.M.1    Nosek, L.2    de la Pena, A.3
  • 15
    • 0030614874 scopus 로고    scopus 로고
    • Time-action profile of inhaled insulin
    • Heinemann L, Traut T, Heise T. Time-action profile of inhaled insulin. Diabet Med 1997; 14:63-72.
    • (1997) Diabet Med , vol.14 , pp. 63-72
    • Heinemann, L.1    Traut, T.2    Heise, T.3
  • 16
    • 4644372272 scopus 로고    scopus 로고
    • Efficacy and safety of inhaled insulin (Exubera) compared with subcutaneous insulin therapy in patients with type 2 diabetes: Results of a 6-month, randomized, comparative trial
    • Hollander PA, Blonde L, Rowe R, et al. Efficacy and safety of inhaled insulin (Exubera) compared with subcutaneous insulin therapy in patients with type 2 diabetes: results of a 6-month, randomized, comparative trial. Diabetes Care 2004; 27:2356-2362.
    • (2004) Diabetes Care , vol.27 , pp. 2356-2362
    • Hollander, P.A.1    Blonde, L.2    Rowe, R.3
  • 17
    • 4344652690 scopus 로고    scopus 로고
    • Intrasubject variability of inhaled insulin in type 1 diabetes: A comparison with subcutaneous insulin
    • Kapitza C, Hompesch M, Scharling B, Heise T. Intrasubject variability of inhaled insulin in type 1 diabetes: a comparison with subcutaneous insulin. Diabetes Technol Ther 2004; 6:466-472.
    • (2004) Diabetes Technol Ther , vol.6 , pp. 466-472
    • Kapitza, C.1    Hompesch, M.2    Scharling, B.3    Heise, T.4
  • 19
    • 18144368866 scopus 로고    scopus 로고
    • Time-action profile of inhaled insulin in comparison with subcutaneously injected insulin lispro and regular human insulin
    • Rave K, Bott S, Heinemann L, et al. Time-action profile of inhaled insulin in comparison with subcutaneously injected insulin lispro and regular human insulin. Diabetes Care 2005; 28:1077-1082.
    • (2005) Diabetes Care , vol.28 , pp. 1077-1082
    • Rave, K.1    Bott, S.2    Heinemann, L.3
  • 20
    • 0029847551 scopus 로고    scopus 로고
    • Intrapulmonary administration of insulin to healthy volunteers
    • Jendle J, Karlberg B. Intrapulmonary administration of insulin to healthy volunteers. J Intern Med 1996; 240:93-98.
    • (1996) J Intern Med , vol.240 , pp. 93-98
    • Jendle, J.1    Karlberg, B.2
  • 21
    • 0033851983 scopus 로고    scopus 로고
    • Intra-individual variability of the metabolic effect of inhaled insulin together with an absorption enhancer
    • Heinemann L, Klappoth W, Rave K, Hompesch B, Linkeschowa R, Heise T. Intra-individual variability of the metabolic effect of inhaled insulin together with an absorption enhancer. Diabetes Care 2000; 23:1343-1347.
    • (2000) Diabetes Care , vol.23 , pp. 1343-1347
    • Heinemann, L.1    Klappoth, W.2    Rave, K.3    Hompesch, B.4    Linkeschowa, R.5    Heise, T.6
  • 22
    • 33745064779 scopus 로고    scopus 로고
    • Pfizer. Insulin Exubera US Package Insert
    • Pfizer. Insulin Exubera US Package Insert, 2006.
    • (2006)
  • 23
    • 7444270287 scopus 로고    scopus 로고
    • Efficacy and safety of inhaled insulin (Exubera) compared with subcutaneous insulin therapy in patients with type 1 diabetes: Results of a 6-month, randomized, comparative trial
    • Exubera Phase III Study Group. al
    • Quattrin T, Belanger A, Bohannon NJ, Schwartz SL; Exubera Phase III Study Group. al. Efficacy and safety of inhaled insulin (Exubera) compared with subcutaneous insulin therapy in patients with type 1 diabetes: results of a 6-month, randomized, comparative trial. Diabetes Care 2004; 27:2622-2627.
    • (2004) Diabetes Care , vol.27 , pp. 2622-2627
    • Quattrin, T.1    Belanger, A.2    Bohannon, N.J.3    Schwartz, S.L.4
  • 24
    • 21544464003 scopus 로고    scopus 로고
    • Use of inhaled insulin in a basal/bolus insulin regimen in type 1 diabetic subjects: A 6-month, randomized, comparative trial
    • Inhaled Insulin Phase III Type 1 Diabetes Study Group
    • Skyler JS, Weinstock RS, Raskin P, et al; Inhaled Insulin Phase III Type 1 Diabetes Study Group. Use of inhaled insulin in a basal/bolus insulin regimen in type 1 diabetic subjects: a 6-month, randomized, comparative trial. Diabetes Care 2005; 28:1630-1635.
    • (2005) Diabetes Care , vol.28 , pp. 1630-1635
    • Skyler, J.S.1    Weinstock, R.S.2    Raskin, P.3
  • 25
    • 0035814836 scopus 로고    scopus 로고
    • Inhaled human insulin treatment in patients with type 2 diabetes mellitus
    • Inhaled Insulin Study Group
    • Cefalu WT, Skyler JS, Kourides IA, et al; Inhaled Insulin Study Group. Inhaled human insulin treatment in patients with type 2 diabetes mellitus. Ann Intern Med 2001; 134:203-207.
    • (2001) Ann Intern Med , vol.134 , pp. 203-207
    • Cefalu, W.T.1    Skyler, J.S.2    Kourides, I.A.3
  • 26
    • 1042303481 scopus 로고    scopus 로고
    • Intensive therapy with inhaled insulin via the AERx insulin diabetes management system: A 12-week proof-of-concept trial in patients with type 2 diabetes
    • Hermansen K, Ronnemaa T, Petersen AH, Bellaire S, Adamson U. Intensive therapy with inhaled insulin via the AERx insulin diabetes management system: a 12-week proof-of-concept trial in patients with type 2 diabetes. Diabetes Care 2004; 27:162-167.
    • (2004) Diabetes Care , vol.27 , pp. 162-167
    • Hermansen, K.1    Ronnemaa, T.2    Petersen, A.H.3    Bellaire, S.4    Adamson, U.5
  • 27
    • 26944435504 scopus 로고    scopus 로고
    • Inhaled insulin improves glycemic control when substituted for or added to oral combination therapy in type 2 diabetes: A randomized, controlled trial
    • Rosenstock J, Zinman B, Murphy LJ, et al. Inhaled insulin improves glycemic control when substituted for or added to oral combination therapy in type 2 diabetes: a randomized, controlled trial. Ann Intern Med 2005; 143:549-558.
    • (2005) Ann Intern Med , vol.143 , pp. 549-558
    • Rosenstock, J.1    Zinman, B.2    Murphy, L.J.3
  • 28
    • 23044488164 scopus 로고    scopus 로고
    • Efficacy of inhaled insulin in patients with type 2 diabetes not controlled with diet and exercise: A 12-week, randomized, comparative trial
    • Exubera Phase III Study Group
    • DeFronzo RA, Bergenstal RM, Cefalu WT, et al; Exubera Phase III Study Group. Efficacy of inhaled insulin in patients with type 2 diabetes not controlled with diet and exercise: a 12-week, randomized, comparative trial. Diabetes Care 2005; 28:1922-1928.
    • (2005) Diabetes Care , vol.28 , pp. 1922-1928
    • DeFronzo, R.A.1    Bergenstal, R.M.2    Cefalu, W.T.3
  • 29
    • 0025282127 scopus 로고
    • Aerosols for systemic treatment
    • Kohler D. Aerosols for systemic treatment. Lung 1990; 168(suppl):677-684.
    • (1990) Lung , vol.168 , Issue.SUPPL. , pp. 677-684
    • Kohler, D.1
  • 31
    • 22144441074 scopus 로고    scopus 로고
    • The effect of smoking cessation and subsequent resumption on absorption of inhaled insulin (Exubera)
    • [Abstract]
    • Becker RHA, Sha S, Frick AD, Piechatzek R. The effect of smoking cessation and subsequent resumption on absorption of inhaled insulin (Exubera) [Abstract]. Diabetes 2003; 52:A37.
    • (2003) Diabetes , vol.52
    • Becker, R.H.A.1    Sha, S.2    Frick, A.D.3    Piechatzek, R.4
  • 32
    • 33745067717 scopus 로고    scopus 로고
    • Department of Health and Human Services Food And Drug Administration Center for Drug Evaluation and Research Endocrinologic and Metabolic Drugs Advisory Committee www.fda.gov/ohrms/dockets/ac/05/transcripts /2005-4169T1.pdf. Transcript of the meeting of Thursday, September 8
    • Department of Health and Human Services Food And Drug Administration Center for Drug Evaluation and Research Endocrinologic and Metabolic Drugs Advisory Committee. www.fda.gov/ohrms/dockets/ac/05/transcripts/ 2005-4169T1.pdf. Transcript of the meeting of Thursday, September 8, 2005.
    • (2005)
  • 33
    • 0038248885 scopus 로고    scopus 로고
    • Inhaled insulin using the AERx Insulin Diabetes Management System in healthy and asthmatic subjects
    • Henry RR, Mudaliar SIR, Howland WC 3rd, et al. Inhaled insulin using the AERx Insulin Diabetes Management System in healthy and asthmatic subjects. Diabetes Care 2003; 26:764-769.
    • (2003) Diabetes Care , vol.26 , pp. 764-769
    • Henry, R.R.1    Mudaliar, S.R.2    Howland III, W.C.3
  • 34
    • 18244365084 scopus 로고    scopus 로고
    • Influence of acute upper respiratory tract infection on the absorption of inhaled insulin using the AERx Insulin Diabetes Management System
    • McElduff A, Mather LE, Kam PC, Clauson P. Influence of acute upper respiratory tract infection on the absorption of inhaled insulin using the AERx Insulin Diabetes Management System. Br J Clin Pharmacol 2005; 59:546-551.
    • (2005) Br J Clin Pharmacol , vol.59 , pp. 546-551
    • McElduff, A.1    Mather, L.E.2    Kam, P.C.3    Clauson, P.4
  • 36
    • 0036120714 scopus 로고    scopus 로고
    • Insulin inhibits apoptosis of macrophage cell line, THP-1 cells, via phosphatidylinositol-3-kinase-dependent pathway
    • lida K, Suzuki H, Sone H, et al. Insulin inhibits apoptosis of macrophage cell line, THP-1 cells, via phosphatidylinositol-3-kinase-dependent pathway. Arterioscler Thromb Vasc Biol 2002; 22:380-386.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 380-386
    • Lida, K.1    Suzuki, H.2    Sone, H.3
  • 37
    • 0035798916 scopus 로고    scopus 로고
    • Efficacy of inhaled human insulin in type 1 diabetes mellitus: A randomised proof-of-concept study
    • Skyler JS, Cefalu WT, Kourides IA, et al. Efficacy of inhaled human insulin in type 1 diabetes mellitus: a randomised proof-of-concept study. Lancet 2001; 357:331-335.
    • (2001) Lancet , vol.357 , pp. 331-335
    • Skyler, J.S.1    Cefalu, W.T.2    Kourides, I.A.3
  • 38
    • 0142243294 scopus 로고    scopus 로고
    • Inhaled insulin provides improved glycemic control in patients with type 2 diabetes mellitus inadequately controlled with oral agents: A randomized controlled trial
    • Inhaled Insulin Phase II Study Group
    • Weiss SR, Cheng SL, Kourides IA, Gelfand RA, Landschulz WH; Inhaled Insulin Phase II Study Group. Inhaled insulin provides improved glycemic control in patients with type 2 diabetes mellitus inadequately controlled with oral agents: a randomized controlled trial. Arch Intern Med 2003; 163:2277-2282.
    • (2003) Arch Intern Med , vol.163 , pp. 2277-2282
    • Weiss, S.R.1    Cheng, S.L.2    Kourides, I.A.3    Gelfand, R.A.4    Landschulz, W.H.5
  • 39
    • 21244462394 scopus 로고    scopus 로고
    • Antibody response to inhaled insulin in patients with type 1 or type 2 diabetes. An analysis of initial phase II and III inhaled insulin (Exubera) trials and a two-year extension trial
    • Fineberg SE, Kawabata T, Finco-Kent D, Liu C, Krasner A. Antibody response to inhaled insulin in patients with type 1 or type 2 diabetes. An analysis of initial phase II and III inhaled insulin (Exubera) trials and a two-year extension trial. J Clin Endocrinol Metab 2005; 90:3287-3294.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 3287-3294
    • Fineberg, S.E.1    Kawabata, T.2    Finco-Kent, D.3    Liu, C.4    Krasner, A.5
  • 40
    • 24144461892 scopus 로고    scopus 로고
    • The effect of insulin antibodies on the metabolic action of inhaled and subcutaneous insulin: A prospective randomized pharmacodynamic study
    • Heise T, Bott S, Tusek C, et al. The effect of insulin antibodies on the metabolic action of inhaled and subcutaneous insulin: a prospective randomized pharmacodynamic study. Diabetes Care 2005; 28:2161-2169.
    • (2005) Diabetes Care , vol.28 , pp. 2161-2169
    • Heise, T.1    Bott, S.2    Tusek, C.3
  • 41
    • 0035458867 scopus 로고    scopus 로고
    • Treatment satisfaction with inhaled insulin in patients with type 1 diabetes: A randomized controlled trial
    • Gerber RA, Cappelleri JC, Kourides IA, Gelfand RA. Treatment satisfaction with inhaled insulin in patients with type 1 diabetes: a randomized controlled trial. Diabetes Care 2001; 24:1556-1559.
    • (2001) Diabetes Care , vol.24 , pp. 1556-1559
    • Gerber, R.A.1    Cappelleri, J.C.2    Kourides, I.A.3    Gelfand, R.A.4
  • 42
    • 0036245372 scopus 로고    scopus 로고
    • Treatment satisfaction in type 2 diabetes: A comparison between an inhaled insulin regimen and a subcutaneous insulin regimen
    • Cappelleri JC, Cefalu WT, Rosenstock J, Kourides IA, Gerber RA. Treatment satisfaction in type 2 diabetes: a comparison between an inhaled insulin regimen and a subcutaneous insulin regimen. Clin Ther 2002; 24:552-564.
    • (2002) Clin Ther , vol.24 , pp. 552-564
    • Cappelleri, J.C.1    Cefalu, W.T.2    Rosenstock, J.3    Kourides, I.A.4    Gerber, R.A.5
  • 43
    • 12344317702 scopus 로고    scopus 로고
    • Compliance with inhaled insulin treatment using the AERx iDMS Insulin Diabetes Management System
    • Cramer JA, Okikawa J, Bellaire S, Clauson P. Compliance with inhaled insulin treatment using the AERx iDMS Insulin Diabetes Management System. Diabetes Technol Ther 2004; 6:800-807.
    • (2004) Diabetes Technol Ther , vol.6 , pp. 800-807
    • Cramer, J.A.1    Okikawa, J.2    Bellaire, S.3    Clauson, P.4
  • 44
    • 19944431309 scopus 로고    scopus 로고
    • Availability of inhaled insulin promotes greater perceived acceptance of insulin therapy in patients with type 2 diabetes
    • Freemantle N, Blonde L, Duhot D, et al. Availability of inhaled insulin promotes greater perceived acceptance of insulin therapy in patients with type 2 diabetes. Diabetes Care 2005; 28:427-428.
    • (2005) Diabetes Care , vol.28 , pp. 427-428
    • Freemantle, N.1    Blonde, L.2    Duhot, D.3


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