Reduced coronary reserve in response to short-term ischaemia and vasoactive drugs in ex vivo hearts from diabetic mice

Acta Physiologica

Volumn 186, Issue 3, 2006, Pages 171-177

  Bratkovsky, S V ^a   Aasum, E ^a   Riemersma, R A ^b   Myhre, E S P ^a   Larsen, T S ^a  

^a UNIVERSITY OF TROMSØ   (Norway)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Coronary flow; Diabetic mouse hearts; Reactive hyperaemia; Vasoactive drugs

Indexed keywords

ADENOSINE; BICARBONATE; BUFFER; NITRIC OXIDE; NITROPRUSSIDE SODIUM; VASOACTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELLULAR DISTRIBUTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DRUG RESPONSE; HEART MUSCLE ISCHEMIA; HEART PERFUSION; HYPEREMIA; MEASUREMENT; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PH; PRIORITY JOURNAL; SMOOTH MUSCLE RELAXATION;

ADENOSINE; ANIMALS; BODY WEIGHT; CORONARY CIRCULATION; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; HYPOGLYCEMIC AGENTS; LAURIC ACIDS; MICE; MICE, INBRED C57BL; MYOCARDIAL ISCHEMIA; NITROPRUSSIDE; ORGAN CULTURE TECHNIQUES; VASODILATOR AGENTS;

EID: 33745078105     PISSN: 17481708     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1748-1716.2006.01527.x     Document Type: Article

References (37)

1. Aasum E. Belke D.D. Severson D.L., et al. 2002. Cardiac function and metabolism in Type 2 diabetic mice after treatment with BM 17.0744, a novel PPAR-alpha activator. Am J Physiol Heart Circ Physiol 283, H949 H957.
2. Aasum E. Hafstad A.D. Larsen T.S. 2003a. Changes in substrate metabolism in isolated mouse hearts following ischemia-reperfusion. Mol Cell Biochem 249, 97 103.
3. Aasum E. Hafstad A.D. Severson D.L. Larsen T.S. 2003b. Age-dependent changes in metabolism, contractile function, and ischemic sensitivity in hearts from db/db mice. Diabetes 52, 434 441.
4. Akatsuka Y. Egashira K. Katsuda Y. Narishige T. Ueno H. Shimokawa H. Takeshita A. 1994. ATP sensitive potassium channels are involved in adenosine A2 receptor mediated coronary vasodilatation in the dog. Cardiovasc Res 28, 906 911.
5. Aversano T. Ouyang P. Silverman H. 1991. Blockade of the ATP-sensitive potassium channel modulates reactive hyperemia in the canine coronary circulation. Circ Res 69, 618 622.
6. Belke D.D. Larsen T.S. Gibbs E.M. Severson D.L. 2000. Altered metabolism causes cardiac dysfunction in perfused hearts from diabetic (db/db) mice. Am J Physiol Endocrinol Metab 279, E1104 E1113.
7. Bratkovsky S. Aasum E. Birkeland C.H. Riemersma R.A. Myhre E.S. Larsen T.S. 2004. Measurement of coronary flow reserve in isolated hearts from mice. Acta Physiol Scand 181, 167 172.
8. Candido R. Forbes J.M. Thomas M.C. et al. 2003. A breaker of advanced glycation end products attenuates diabetes-induced myocardial structural changes. Circ Res 92, 785 792.
9. Canty J.M. Jr. Schwartz J.S. 1994. Nitric oxide mediates flow-dependent epicardial coronary vasodilation to changes in pulse frequency but not mean flow in conscious dogs. Circulation 89, 375 384.
10. Coleman D.L. 1982. Diabetes-obesity syndromes in mice. Diabetes 31 ( Suppl 1 1 6.
11. Coleman D. Hummel K. 1974. Hyperinsulinemia in pre-weaning diabetic (db) mice. Diabetologia 10, 607 610.
12. Daut J. Maier-Rudolph W. von Beckerath N. Mehrke G. Gunther K. Goedel-Meinen L. 1990. Hypoxic dilation of coronary arteries is mediated by ATP-sensitive potassium channels. Science 247, 1341 1344.
13. de Vriese A.S. Verbeuren T.J. van de Voorde J. Lameire N.H. Vanhoutte P.M. 2000. Endothelial dysfunction in diabetes. Br J Pharmacol 130, 963 974.
14. di Carli M.F. Bianco-Batlles D. Landa M.E., et al. 1999. Effects of autonomic neuropathy on coronary blood flow in patients with diabetes mellitus. Circulation 100, 813 819.
15. Duncker D.J. van Zon N.S. Pavek T.J. Herrlinger S.K. Bache R.J. 1995. Endogenous adenosine mediates coronary vasodilation during exercise after K(ATP)+ channel blockade. J Clin Invest 95, 285 295.
16. Fein F.S. Zola B.E. Malhotra A. Cho S. Factor S.M. Scheuer J. Sonnenblick E.H. 1990. Hypertensive-diabetic cardiomyopathy in rats. Am J Physiol 258, H793 H805.
17. Grundy S.M. Benjamin I.J. Burke G.L. et al. 1999. Diabetes and cardiovascular disease: a statement for healthcare professionals from the American Heart Association. Circulation 100, 1134 1146.
18. Iino K. Yoshinari M. Yamamoto M., et al. 1996. Effect of glycated collagen on proliferation of human smooth muscle cells in vitro. Diabetologia 39, 800 806.
19. Kostic M.M. Schrader J. 1992. Role of nitric oxide in reactive hyperemia of the guinea pig heart. Circ Res 70, 208 212.
20. Kristiansen S.B. Løfgren B. Støttrup N.B. et al. 2004. Ischaemic preconditioning does not protect the heart in obese and lean animal models of Type 2 diabetes. Diabetologia 47, 1716 1721.
21. Kuo L. Chancellor J.D. 1995. Adenosine potentiates flow-induced dilation of coronary arterioles by activating KATP channels in endothelium. Am J Physiol 269, H541 H549.
22. Leibel R.L. 1997. Single gene obesities in rodents: possible relevance to human obesity. J Nutr 127, 1908S.
23. Meyer K. Voss E. Neidlein R. Kuhnle H. Pill J. 1998. omega-Substituted alkyl carboxylic acids as antidiabetic and lipid-lowering agents. Eur J Med Chem 33, 775 787.
24. Mutafova-Yambolieva V.N. Keef K.D. 1997. Adenosine-induced hyperpolarization in guinea pig coronary artery involves A2b receptors and KATP channels. Am J Physiol 273, H2687 H2695.
25. Nahser P.J. Jr. Brown R.E. Oskarsson H. Winniford M.D. Rossen J.D. 1995. Maximal coronary flow reserve and metabolic coronary vasodilation in patients with diabetes mellitus. Circulation 91, 635 640.
26. Nitenberg A. Valensi P. Sachs R. Dali M. Aptecar E. Attali J.R. 1993. Impairment of coronary vascular reserve and ACh-induced coronary vasodilation in diabetic patients with angiographically normal coronary arteries and normal left ventricular systolic function. Diabetes 42, 1017 1025.
27. Olsson R.A. Pearson J.D. 1990. Cardiovascular purinoceptors. Physiol Rev 70, 761 845.
28. Perfetto F. Tarquini R. Tapparini L. Tarquini B. 1998. Influence of non-insulin-dependent diabetes mellitus on plasma endothelin-1 levels in patients with advanced atherosclerosis. J Diabetes Complicat 12, 187 192.
29. Piatti P.M. Monti L.D. Galli L. et al. 2000. Relationship between endothelin-1 concentration and metabolic alterations typical of the insulin resistance syndrome. Metabolism 49, 748 752.
30. Pill J. Kuhnle H.F. 1999. BM 17.0744: a structurally new antidiabetic compound with insulin-sensitizing and lipid-lowering activity. Metabolism 48, 34 40.
31. Pitkanen O.P. Nuutila P. Raitakari O.T. 1998. Coronary flow reserve is reduced in young men with IDDM. Diabetes 47, 248 254.
32. Shehadeh A. Regan T.J. 1995. Cardiac consequences of diabetes mellitus. Clin Cardiol 18, 301 305.
33. Sheetz M.J. King G.L. 2002. Molecular understanding of hyperglycemia's adverse effects for diabetic complications. JAMA 288, 2579 2588.
34. Steinberg H.O. Chaker H. Leaming R. Johnson A. Brechtel G. Baron A.D. 1996. Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance. J Clin Invest 97, 2601 2610.
35. Steinberg H.O. Tarshoby M. Monestel R. et al. 1997. Elevated circulating free fatty acid levels impair endothelium-dependent vasodilation. J Clin Invest 100, 1230 1239.
36. Sundell J. Laine H. Nuutila P. et al. 2002. The effects of insulin and short-term hyperglycemia on myocardial blood flow in young men with uncomplicated type 1 diabetes. Diabetologia 45, 775 782.
37. Vials A. Burnstock G. 1993. A2-purinoceptor-mediated relaxation in the guinea-pig coronary vasculature: a role for nitric oxide. Br J Pharmacol 109, 424 429.