Retinol-binding protein 4, insulin resistance, and type 2 diabetes

New England Journal of Medicine

Volumn 354, Issue 24, 2006, Pages 2596-2598

  Polonsky, Kenneth S ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOCYTOKINE; CALPAIN 10; CELL NUCLEUS RECEPTOR; CYSTEINE PROTEINASE; FATTY ACID; GLUCOSE; GLUCOSE TRANSPORTER 4; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; INSULIN; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; POTASSIUM CHANNEL; PROGLUCAGON; RESISTIN; RETINOL BINDING PROTEIN; TRANSCRIPTION FACTOR; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; WNT PROTEIN;

CALORIC INTAKE; CELL FUNCTION; CLINICAL FEATURE; DISEASE ASSOCIATION; DISEASE SEVERITY; DNA POLYMORPHISM; EDITORIAL; ENVIRONMENTAL FACTOR; FAT INTAKE; GENE IDENTIFICATION; GENETIC VARIABILITY; GLUCONEOGENESIS; HUMAN; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIFESTYLE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RISK FACTOR; TARGET ORGAN; TRIACYLGLYCEROL BLOOD LEVEL;

ADIPOSE TISSUE; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; GLUCOSE METABOLISM DISORDERS; GLUCOSE TRANSPORTER TYPE 4; HUMANS; INSULIN RESISTANCE; OBESITY; RETINOL-BINDING PROTEINS;

EID: 33745075360     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMe068091     Document Type: Editorial

References (3)

1. Grant SFA, Thorleifsson G, Reynidottir I, et al. Variant of transcription factor 7-like 2 (TCFL2) gene confers risk of type 2 diabetes. Nat Genet 2006;38:320-3.
2. Graham TE, Yang Q, Bluher M, et al. Retinol-binding protein 4 and insulin resistance in lean and obese subjects and subjects with type 2 diabetes. N Engl J Med 2006;354:2552-63.
3. Yang Q, Graham TE, Mody N, et al. Serum retinol binding protein contributes to insulin resistance in obesity and type 2 diabetes. Nature 2005;436:356-62.