Population pharmacokinetic modelling of carbamazepine in epileptic elderly patients: Implications for dosage

Journal of Clinical Pharmacy and Therapeutics

Volumn 31, Issue 3, 2006, Pages 211-221

  Bondareva, I B ^a   Jelliffe, R W ^b   Gusev, E I ^c   Guekht, A B ^c   Melikyan, E G ^c   Belousov, Y B ^c  

^a FEDERAL RESEARCH AND CLINICAL CENTER OF PHYSICAL CHEMICAL MEDICINE OF FEDERAL MEDICAL BIOLOGICAL AGENCY   (Russian Federation)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c PIROGOV RUSSIAN NATIONAL RESEARCH MEDICAL UNIVERSITY   (Russian Federation)

Author keywords

Carbamazepine pharmacokinetics; Elderly patients; Population modelling; Therapeutic drug monitoring

Indexed keywords

CARBAMAZEPINE;

ADULT; AGED; ARTICLE; CHRONIC DRUG ADMINISTRATION; COMPARATIVE STUDY; COMPUTER PROGRAM; CONTROLLED STUDY; DOSE CALCULATION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DOSE REGIMEN; DRUG METABOLISM; DRUG MONITORING; DRUG USE; EPILEPSY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; METABOLIC CLEARANCE RATE; MONOTHERAPY; NONPARAMETRIC TEST; POPULATION MODEL; SENESCENCE; STATISTICAL MODEL; STATISTICAL SIGNIFICANCE; STEADY STATE; TREATMENT PLANNING;

ADULT; AGED; AGING; ANTICONVULSANTS; BAYES THEOREM; CARBAMAZEPINE; DATABASES, FACTUAL; EPILEPSY; FEMALE; HUMANS; LINEAR MODELS; MALE; MIDDLE AGED; MODELS, STATISTICAL; POPULATION; RETROSPECTIVE STUDIES; SEIZURES;

EID: 33745048527     PISSN: 02694727     EISSN: 13652710     Source Type: Journal    
DOI: 10.1111/j.1365-2710.2006.00717.x     Document Type: Article

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