Upregulation of glial cell line-derived neurotrophic factor and artemin mRNA in the auditory nerve of deafened rats

NeuroReport

Volumn 17, Issue 9, 2006, Pages 875-878

  Wissel, Kirsten ^a   Wefstaedt, Patrick ^a   Rieger, Heike ^a   Miller, Josef M ^b   Lenarz, Thomas ^a   Stöver, Timo ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

Glial cell line derived neurotrophic factor family; Inferior colliculus; Inner ear; Neomycin induced deafness; Semiquantitative reverse transcriptase polymerase chain reaction

Indexed keywords

ARTEMIN; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR RECEPTOR; MESSENGER RNA; NEURTURIN; PROTEIN RET; RECEPTOR SUBTYPE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; COCHLEAR NERVE; CONTROLLED STUDY; GENE EXPRESSION; HEARING IMPAIRMENT; INFERIOR COLLICULUS; MALE; MULTIGENE FAMILY; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FAMILY; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

ACOUSTIC STIMULATION; ANIMALS; COCHLEAR NERVE; DEAFNESS; DISEASE MODELS, ANIMAL; GENE EXPRESSION; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; INFERIOR COLLICULUS; MALE; NERVE TISSUE PROTEINS; RATS; RATS, INBRED LEW; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; UP-REGULATION;

EID: 33745038739     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.wnr.0000221836.26093.85     Document Type: Article

References (23)

1. Sariola H, Saarma M. Novel functions and signalling pathways for GDNF. J Cell Sci 2003; 116:3855-3862.
2. Fritzsch B, Pirvola U, Ylikoski J. Making and breaking the innervation of the ear: neurotrophic support during ear development and its clinical implications. Cell Tissue Res 1999; 295:369-382.
3. Miller JM, Chi DH, O'Keeffe LJ, Kruszka P, Raphael Y, Altschuler RA. Neurotrophins can enhance spiral ganglion cell survival after inner hair cell loss. Int J Dev Neurosci 1997; 15:631-643.
4. Ylikoski J, Pirvola U, Virkkala J, Suvanto P, Liang XQ, Magal E, et al. Guinea pig auditory neurons are protected by glial cell line-derived growth factor from degeneration after noise trauma. Hear Res 1998; 124:17-26.
5. Kawamoto K, Yagi M, Stöver T, Kanzaki S, Raphael Y. Hearing and hair cells are protected by adenoviral gene therapy with TGFβ-1 and GDNF. Mol Ther 2003; 7:484-492.
6. Webster M, Webster DB. Spiral ganglion neuron loss following organ of Corti loss: a quantitative study. Brain Res 1981; 212:17-30.
7. Mattson MP, Keller JN, Begley JG. Evidence for synaptic apoptosis. Exp Neurol 1998; 153:35-48.
8. Yamagati T, Miller JM, Ulfendahl M, Olivius NP, Altschuler RA, Pyykko I, Bredberg G. Delayed neurotrophic treatment preserves nerve survival and electrophysiological responsiveness in neomycin-deafened guinea pigs. J Neurosci Res 2004; 78:75-86.
9. Treanor JJ, Goodman L, de Sauvage F, Stone DM, Poulsen KT, Beck CD, et al. Characterization of a multicomponent receptor for GDNF Nature 1996; 382:80-83.
10. Creedon DJ, Tansey MG, Baloh RH, Osborne PA, Lampe PA, Fahrner TJ, et al. Neurturin shares receptors and signal transduction pathways with glial cell line-derived neurotrophic factor in sympathetic neurons. Proc Natl Acad Sci USA 1997; 94:7018-7023.
11. Baloh RH, Tansey MG, Lampe PA, Fahrner TJ, Enomoto H, Simburger KS, et al. Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex. Neuron 1998; 121:291-302.
12. Stöver T, Gong TL, Cho Y, Altschuler RA, Lomax MI. Expression of the GDNF family members and their receptors in the mature rat cochlea. Brain Res Mol Brain Res 2000; 76:25-35.
13. Henke W, Herdel K, Jung K, Schnorr D, Loening SA. Betaine improves the PCR amplification of GC-rich DNA sequences. Nucleic Acids Res 1997; 25:3957-3958.
14. Shinohara T, Bredberg G, Ulfendahl M, Pyykkö I, Olivius NP, Kaksonen R, et al. Neurotrophic factor intervention restores auditory function in deafened animals. Proc Natl Acad Sci 2002; 99:1657-1660.
15. Springer JE, Kitzman PH. Neuroprotective strategies involving the neurotrophins and their signaling pathways. In: Mattson MP, editor. Neuroprotective signal transduction. Tokowa: Humana Press; 1998.
16. Estus S. Gene induction and neuronal apoptosis. In: Mattson MP, editor. Neuroprotective signal transduction. Tokowa: Humana Press; 1998.
17. Estus S, Zaks WJ, Freeman RS, Gruda M, Bravo R, Johnson EM Jr. Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis. J Cell Biol 1994; 127:1717-1727.
18. Stöver T, Nam Y, Gong TL, Lomax MI, Altschuler RA. Glial cell line-derived neurotrophic factor (GDNF) and its receptor complex are expressed in the auditory nerve of the mature rat cochlea. Hear Res 2001; 155:143-151.
19. Masure S, Cik M, Hoefnagel E, Nosrat CA, Van der Linden I, Scott R, et al. Mammalian GFRalpha-4, a divergent member of the GFRalpha family of coreceptors for glial cell line-derived neurotrophic factor family ligands, is a receptor for the neurotrophic factor persephin. J Biol Chem 2000; 275:39427-39434.
20. Thompson J, Doxakis E, Pinon LG, Strachan P, Buj-Bello A, Wyatt S, et al. GFRalpha-4, a new GDNF family receptor. Mol Cell Neurosci. 1998; 11:117-126.
21. Humpel C, Hoffer B, Stromberg I, Bektesh S, Collins F, Olson L. Neurons of the hippocampal formation express glial cell line-derived neurotrophic factor messenger RNA in response to kainate-induced excitation. Neuroscience 1994; 59:791-795.
22. Tokumine J, Sugahara K, Kakinohana O, Marsala M. The spinal GDNF level is increased after transient spinal cord ischemia in the rat. Acta Neurochir Suppl 2003; 86:231-234.
23. Nam YJ, Stöver T, Hartman SS, Altschuler RA. Upregulation of glial cell line-derived neurotrophic factor (GDNF) in the rat cochlea following noise. Hear Res 2000; 146:1-6.