Anchored cAMP signaling: Onward and upward - A short history of compartmentalized cAMP signal transduction

European Journal of Cell Biology

Volumn 85, Issue 7, 2006, Pages 585-592

  Smith, F Donelson ^a   Scott, John D ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

AKAP; cAMP dependent protein kinase; Compartmentalization; Phosphodiesterase; PKA; Signal transduction

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN; GLYCOGEN; HORMONE RECEPTOR; PHOSPHODIESTERASE IV;

CELL COMPARTMENTALIZATION; COMPLEX FORMATION; ENZYME ACTIVATION; FLUORESCENCE RESONANCE ENERGY TRANSFER; GLYCOGEN METABOLISM; IMMUNOCYTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEOMICS; REVIEW; SECOND MESSENGER; SIGNAL TRANSDUCTION;

EID: 33745022408     PISSN: 01719335     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejcb.2006.01.011     Document Type: Review

References (73)

1. Adams S.R., Harootunian A.T., Buechler Y.J., Taylor S.S., and Tsien R.Y. Fluorescence ratio imaging of cyclic AMP in single cells. Nature 349 (1991) 694-697
2. Beavo J.A., Hardman J.G., and Sutherland E.W. Stimulation of adenosine 3′,5′-monophosphate hydrolysis by guanosine 3′,5′-monophosphate. J. Biol. Chem. 246 (1971) 3841-3846
3. Benovic J.L., Strasser R.H., Caron M.G., and Lefkowitz R.J. Beta-adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor. Proc. Natl. Acad. Sci. USA 83 (1986) 2797-2801
4. Blagoev B., Ong S.E., Kratchmarova I., and Mann M. Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics. Nat. Biotechnol. 22 (2004) 1139-1145
5. Bregman D.B., Bhattacharyya N., and Rubin C.S. High affinity binding protein for the regulatory subunit of cAMP-dependent protein kinase II-B. Cloning, characterization, and expression of cDNAs for rat brain P150. J. Biol. Chem. 264 (1989) 4648-4656
6. Burnett G., and Kennedy E.P. The enzymatic phosphorylation of proteins. J. Biol. Chem. 211 (1954) 969-980
7. Buxton I.L., and Brunton L.L. Compartments of cyclic AMP and protein kinase in mammalian cardiomyocytes. J. Biol. Chem. 258 (1983) 10233-10239
8. Carnegie G.K., Smith F.D., McConnachie G., Langeberg L.K., and Scott J.D. AKAP-Lbc nucleates a protein kinase D activation scaffold. Mol. Cell 15 (2004) 889-899
9. Carr D.W., Stofko-Hahn R.E., Fraser I.D., ishop S.M., Acott T.S., Brennan R.G., and Scott J.D. Interaction of the regulatory subunit (RII) of cAMP-dependent protein kinase with RII-anchoring proteins occurs through an amphipathic helix binding motif. J. Biol. Chem. 266 (1991) 14188-14192
10. Carr D.W., Hausken Z.E., Fraser I.D., Stofko-Hahn R.E., and Scott J.D. Association of the type II cAMP-dependent protein kinase with a human thyroid RII-anchoring protein. Cloning and characterization of the RII-binding domain. J. Biol. Chem. 267 (1992) 13376-13382
11. Coghlan V.M., Perrino B.A., Howard M., Langeberg L.K., Hicks J.B., Gallatin W.M., and Scott J.D. Association of protein kinase A and protein phosphatase 2B with a common anchoring protein. Science 267 (1995) 108-111
12. Conti M., Kasson B.G., and Hsueh A.J. Hormonal regulation of 3′,5′-adenosine monophosphate phosphodiesterases in cultured rat granulosa cells. Endocrinology 114 (1984) 2361-2368
13. Corbin J.D., and Keely S.L. Characterization and regulation of heart adenosine 3′:5′-monophosphate-dependent protein kinase isozymes. J. Biol. Chem. 252 (1977) 910-918
14. Corbin J.D., Keely S.L., Soderling T.R., and Park C.R. Hormonal regulation of adenosine 3′,5′-monophosphate-dependent protein kinase. Adv. Cyclic Nucleotide Res. 5 (1975) 265-279
15. Cori G.T., and Green A.A. Crystalline muscle phosphorylase. II. Prosthetic group. J. Biol. Chem. 151 (1943) 31-38
16. Cori G.T., Colowick S.P., and Cori C.F. The activity of the phosphorylating enzyme in muscle extracts. J. Biol. Chem. 127 (1939) 771-782
17. Danial N.N., Gramm C.F., Scorrano L., Zhang C.Y., Krauss S., Ranger A.M., Datta S.R., Greenberg M.E., Licklider L.J., Lowell B.B., Gygi S.P., and Korsmeyer S.J. BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis. Nature 424 (2003) 952-956
18. de Hoog C.L., and Mann M. Proteomics. Annu. Rev. Genomics Hum. Genet. 5 (2004) 267-293
19. Diviani D., Soderling J., and Scott J.D. AKAP-Lbc anchors protein kinase A and nucleates Galpha 12-selective Rho-mediated stress fiber formation. J. Biol. Chem. 276 (2001) 44247-44257
20. Diviani D., Abuin L., Cotecchia S., and Pansier L. Anchoring of both PKA and 14-3-3 inhibits the Rho-GEF activity of the AKAP-Lbc signaling complex. EMBO J. 23 (2004) 2811-2820
21. Dobrowolska G., Lozeman F.J., Li D., and Krebs E.G. CK2, a protein kinase of the next millennium. Mol. Cell Biochem. 191 (1999) 3-12
22. Dodge K.L., Khouangsathiene S., Kapiloff M.S., Mouton R., Hill E.V., Houslay M.D., Langeberg L.K., and Scott J.D. mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module. EMBO J. 20 (2001) 1921-1930
23. Dodge-Kafka K.L., Soughayer J., Pare G.C., Carlisle Michel J.J., Langeberg L.K., Kapiloff M.S., and Scott J.D. The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways. Nature 437 (2005) 574-578
24. Dougherty M.K., and Morrison D.K. Unlocking the code of 14-3-3. J. Cell Sci. 117 (2004) 1875-1884
25. Eden S., Rohatgi R., Podtelejnikov A.V., Mann M., and Kirschner M.W. Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck. Nature 418 (2002) 790-793
26. Green A.A., and Cori G.T. Crystalline muscle phosphorylase. I. Preparation, properties, and molecular weight. J. Biol. Chem. 151 (1943) 21-29
27. Greengard P. Phosphorylated proteins as physiological effectors. Science 199 (1978) 146-152
28. Gronholm M., Vossebein L., Carlson C.R., Kuja-Panula J., Teesalu T., Alfthan K., Vaheri A., Rauvala H., Herberg F.W., Tasken K., and Carpen O. Merlin links to the cAMP neuronal signaling pathway by anchoring the RIbeta subunit of protein kinase A. J. Biol. Chem. 278 (2003) 41167-41172
29. Hirsch A.H., Glantz S.B., Li Y., You Y., and Rubin C.S. Cloning and expression of an intron-less gene for AKAP 75, an anchor protein for the regulatory subunit of cAMP-dependent protein kinase II beta. J. Biol. Chem. 267 (1992) 2131-2134
30. Hoshi N., Langeberg L.K., and Scott J.D. Distinct enzyme combinations in AKAP signalling complexes permit functional diversity. Nat. Cell Biol. 7 (2005) 1066-1073
31. Huang L.J., Durick K., Weiner J.A., Chun J., and Taylor S.S. D-AKAP2, a novel protein kinase A anchoring protein with a putative RGS domain. Proc. Natl. Acad. Sci. USA 94 (1997) 11184-11189
32. Huang L.J., Durick K., Weiner J.A., Chun J., and Taylor S.S. Identification of a novel protein kinase A anchoring protein that binds both type I and type II regulatory subunits. J. Biol. Chem. 272 (1997) 8057-8064
33. Ingebritsen T.S., and Cohen P. Protein phosphatases: properties and role in cellular regulation. Science 221 (1983) 331-338
34. Jin J., Smith F.D., Stark C., Wells C.D., Fawcett J.P., Kulkarni S., Metalnikov P., O'Donnell P., Taylor P., Taylor L., Zougman A., Woodgett J.R., Langeberg L.K., Scott J.D., and Pawson T. Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. Curr. Biol. 14 (2004) 1436-1450
35. Johnson D.A., Akamine P., Radzio-Andzelm E., Madhusudan M., and Taylor S.S. Dynamics of cAMP-dependent protein kinase. Chem. Rev. 101 (2001) 2243-2270
36. Khandelwal R.L., Vandenheede J.R., and Krebs E.G. Purification, properties, and substrate specificities of phosphoprotein phosphatase(s) from rabbit liver. J. Biol. Chem. 251 (1976) 4850-4858
37. Klauck T.M., Faux M.C., Labudda K., Langeberg L.K., Jaken S., and JScott J.D. Coordination of three signaling enzymes by AKAP79, a mammalian scaffold protein. Science 271 (1996) 1589-1592
38. Kuo J.F., and Greengard P. Cyclic nucleotide-dependent protein kinases. IV. Widespread occurrence of adenosine 3′,5′-monophosphate-dependent protein kinase in various tissues and phyla of the animal kingdom. Proc. Natl. Acad. Sci. USA 64 (1969) 1349-1355
39. Leiser M., Rubin C.S., and Erlichman J. Differential binding of the regulatory subunits (RII) of cAMP-dependent protein kinase II from bovine brain and muscle to RII-binding proteins. J. Biol. Chem. 261 (1986) 1904-1908
40. Li H., Degenhardt B., Tobin D., Yao Z.X., Tasken K., and Papadopoulos V. Identification, localization, and function in steroidogenesis of PAP7, a peripheral-type benzodiazepine receptor- and PKA (RIalpha)-associated protein. Mol. Endocrinol. 15 (2001) 2211-2228
41. Lipmann F.A., and Levene P.A. Serinephosphoric acid obtained on hydrolysis of vitellinic acid. J. Biol. Chem. 98 (1932) 109-114
42. Lohmann S.M., DeCamilli P., Einig I., and Walter U. High-affinity binding of the regulatory subunit (RII) of cAMP-dependent protein kinase to microtubule-associated and other cellular proteins. Proc. Natl. Acad. Sci. USA 81 (1984) 6723-6727
43. Lohse M.J., Benovic J.L., Codina J., Caron M.G., and Lefkowitz R.J. beta-Arrestin: a protein that regulates beta-adrenergic receptor function. Science 248 (1990) 1547-1550
44. Manning G., Plowman G.D., Hunter T., and Sudarsanam S. Evolution of protein kinase signaling from yeast to man. Trends Biochem. Sci. 27 (2002) 514-520
45. Marchmont R.J., and Houslay M.D. Insulin trigger, cyclic AMP-dependent activation and phosphorylation of a plasma membrane cyclic AMP phosphodiesterase. Nature 286 (1980) 904-906
46. Muslin A.J., Tanner J.W., Allen P.M., and Shaw A.S. Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine. Cell 84 (1996) 889-897
47. Newlon M.G., Roy M., Morikis D., Hausken Z.E., Coghlan V., Scott J.D., and Jennings P.A. The molecular basis for protein kinase A anchoring revealed by solution NMR. Nat. Struct. Biol. 6 (1999) 222-227
48. Nimmo G.A., and Cohen P. The regulation of glycogen metabolism. Purification and characterisation of protein phosphatase inhibitor-1 from rabbit skeletal muscle. Eur. J. Biochem. 87 (1978) 341-351
49. Rall T.W., and Sutherland E.W. Formation of a cyclic adenine ribonucleotide by tissue particles. J. Biol. Chem. 232 (1958) 1065-1076
50. Reimann E.M., Brostrom C.O., Corbin J.D., King C.A., and Krebs E.G. Separation of regulatory and catalytic subunits of the cyclic 3′,5′-adenosine monophosphate-dependent protein kinase(s) of rabbit skeletal muscle. Biochem. Biophys. Res. Commun. 42 (1971) 187-194
51. Rodbell M., Birnbaumer L., Pohl S.L., and Krans H.M. The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver V. An obligatory role of guanylnucleotides in glucagon action. J. Biol. Chem. 246 (1971) 1877-1882
52. Rodbell M., Krans H.M., Pohl S.L., and Birnbaumer L. The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. IV. Effects of guanylnucleotides on binding of 125I-glucagon. J. Biol. Chem. 246 (1971) 1872-1876
53. Rosenmund C., Carr D.W., Bergeson S.E., Nilaver G., Scott J.D., and Westbrook G.L. Anchoring of protein kinase A is required for modulation of AMPA/kainate receptors on hippocampal neurons. Nature 368 (1994) 853-856
54. Ross E.M., and Gilman A.G. Reconstitution of catecholamine-sensitive adenylate cyclase activity: interactions of solubilized components with receptor-replete membranes. Proc. Natl. Acad. Sci. USA 74 (1977) 3715-3719
55. Ross E.M., and Gilman A.G. Resolution of some components of adenylate cyclase necessary for catalytic activity. J. Biol. Chem. 252 (1977) 6966-6969
56. Scott J.D., Stofko R.E., McDonald J.R., Comer J.D., Vitalis E.A., and Mangili J.A. Type II regulatory subunit dimerization determines the subcellular localization of the cAMP-dependent protein kinase. J. Biol. Chem. 265 (1990) 21561-21566
57. Skalhegg B.S., and Tasken K. Specificity in the cAMP/PKA signaling pathway. Differential expression, regulation, and subcellular localization of subunits of PKA. Front. Biosci. 5 (2000) D678-D693
58. Soderling S.H., and Beavo J.A. Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions. Curr. Opin. Cell Biol. 12 (2000) 174-179
59. Soderling S.H., Binns K.L., Wayman G.A., Davee S.M., Ong S.H., Pawson T., and Scott J.D. The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling. Nat. Cell Biol. 4 (2002) 970-975
60. Sowadski J.M., Nguyen H.X., Anderson D., and Taylor S.S. Crystallization studies of cAMP-dependent protein kinase. Crystals of catalytic subunit diffract to 3.5 Å resolution. J. Mol. Biol. 182 (1985) 617-620
61. Steffen A., Rottner K., Ehinger J., Innocenti M., Scita G., Wehland J., and Stradal T.E. Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation. EMBO J. 23 (2004) 749-759
62. Steinberg S.F., and Brunton L.L. Compartmentation of G protein-coupled signaling pathways in cardiac myocytes. Annu. Rev. Pharmacol. Toxicol. 41 (2001) 751-773
63. Sutherland E.W., and Rall T.W. Fractionation and characterization of a cyclic adenine ribonucleotide formed by tissue particles. J. Biol. Chem. 232 (1958) 1077-1091
64. Tasken K.A., Collas P., Kemmner W.A., Witczak O., Conti M., and Tasken K. Phosphodiesterase 4D and protein kinase A type II constitute a signaling unit in the centrosomal area. J. Biol. Chem. 276 (2001) 21999-22002
65. Taylor S.S., Knighton D.R., Zheng J., Sowadski J.M., Gibbs C.S., and Zoller M.J. A template for the protein kinase family. Trends Biochem. Sci. 18 (1993) 84-89
66. Theurkauf W.E., and Vallee R.B. Molecular characterization of the cAMP-dependent protein kinase bound to microtubule-associated protein 2. J. Biol. Chem. 257 (1982) 3284-3290
67. Uhler M.D., Carmichael D.F., Lee D.C., Chrivia J.C., Krebs E.G., and McKnight G.S. Isolation of cDNA clones coding for the catalytic subunit of mouse cAMP-dependent protein kinase. Proc. Natl. Acad. Sci. USA 83 (1986) 1300-1304
68. Walsh D.A., Perkins J.P., and Krebs E.G. An adenosine 3′,5′-monophosphate-dependant protein kinase from rabbit skeletal muscle. J. Biol. Chem. 243 (1968) 3763-3765
69. Yuan J., Slice L.W., and Rozengurt E. Activation of protein kinase D by signaling through Rho and the alpha subunit of the heterotrimeric G protein G13. J. Biol. Chem. 276 (2001) 38619-38627
70. Zaccolo M., and Pozzan T. Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes. Science 295 (2002) 1711-1715
71. Zaccolo M., De Giorgi F., Cho C.Y., Feng L., Knapp T., Negulescu P.A., Taylor S.S., Tsien R.Y., and Pozzan T. A genetically encoded, fluorescent indicator for cyclic AMP in living cells. Nat. Cell Biol. 2 (2000) 25-29
72. Zhang J., Ma Y., Taylor S.S., and Tsien R.Y. Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering. Proc. Natl. Acad. Sci. USA 98 (2001) 14997-15002
73. Zhang J., Hupfeld C.J., Taylor S.S., Olefsky J.M., and Tsien R.Y. Insulin disrupts beta-adrenergic signalling to protein kinase A in adipocytes. Nature 437 (2005) 569-573