Neurobiology of autism: Study of a sample of autistic children;Neurobiologia dell'autismo: Studio di un campione di soggetti autistici in età evolutiva

Minerva Pediatrica

Volumn 58, Issue 2, 2006, Pages 109-120

  Germano E ^a   Gagliano A ^a,b   Magazu A ^a   Calarese, T ^a   Calabro M E ^a   Bonsignore, M ^a   Tortorella, G ^a   Calamoneri, F ^a  

^a UNIVERSITY OF MESSINA   (Italy)

^b UNIVERSITY OF MESSINA   (Italy)

Author keywords

Autism; Developmental age; Neurobiology

Indexed keywords

AMINO ACID; AMMONIA; ANTIBODY; CALCIUM; CATECHOLAMINE; CREATINE KINASE; LACTIC ACID; PROTEIN; SEROTONIN; URIC ACID;

ARTICLE; AUTISM; ELECTROENCEPHALOGRAM; HUMAN; KARYOTYPE; NEUROBIOLOGY; NEUROPHYSIOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; RADIODIAGNOSIS; SLEEP; WAKEFULNESS;

AUTISTIC DISORDER; BRAIN; CHILD; CHILD, PRESCHOOL; CHROMOSOMES, HUMAN, X; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; FEMALE; HUMANS; KARYOTYPING; MAGNETIC RESONANCE IMAGING; MALE; SEROTONIN;

EID: 33745019668     PISSN: 00264946     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (53)

1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. IV Edition, Text Revision. Washington, DC: American Psychiatric Association; 2000.
2. Volkmar FR, Lord C, Baily A, Schultz RT, Klin A. Autism and pervasive developmental disorders. J Child Psychol Psychiatry 2004;45:135-70.
3. Bailey A, Le Couteur A, Gottesman I, Bolton P, Simonoff E, Yuzda E et al. Autism as a strongly genetic disorder: evidence from a British twin study. Psychol Med 1995;25:63-77.
4. Le Couteur A, Bailey A, Goode S, Pickles A, Robertson S, Gottesman I et al. A broader phenotype of autism: the clinical spectrum in twins. J Child Psychol Psychiatry 1996;37:785-801.
5. Shao Y, Wolpert CM, Raiford KL, Menold MM, Donnelly SL, Ravan SA et al. Genomic screen and follow-up analysis for autistic disorder. Am J Hum Genet 2002;114:99-105.
6. Smalley SL. Genetic influences in autism. Psychiatr Clin North Am 1991;14:125-39.
7. Auranen M, Nieminem T, Majuri S, Vanhala R, Peltonen L, Jarvela I. Analysis of autism susceptibility gene loci on chromosomes 1p, 4p, 6q, 7q, 13q, 15q, 16p, 17q, 19q and 22q in Finnish multiplex families. Mol Psychiatr 2000;5:320-2.
8. Licinio J, Alvarado I. Progress in the genetic of autism. Mol Psychiatr 2002;7:229-30.
9. International Molecolar Genetic Study of Autism Consortium (IMGSAC). A full genome screen for autism with evidence for linkage to a region on chromosome 7q. International Molecular Genetic Study of Autism Consortium. Hum Mol Genet 1998;7:571-8.
10. International Molecolar Genetic Study of Autism Consortium (IMGSAC). A genomewide screen for autism: strong evidence for linkage to chromosomes 2q, 7q and 16p. Am J Hum Genet 2001;69:570-81.
11. Fombonne E, Du Mazubrun C, Cans C, Grandjean H. Autism and associated medical disorders in a French epidemiological survey. J Am Acad Child Adolesc Psychiatry 1997;36:1561-9.
12. Curatolo P, Porfirio MC, Manzi B, Seri S. Autism in tuberous sclerosis. Eur J Paediatr Neurol 2004;8:327-32.
13. Bauman M, Kemper TL. Histoanatomic observations of the brain in early infantile autism. Neurology 1985;35:866-74.
14. Murakami JW, Courchesne E, Press GA, Yeung-Courchesne R, Hesselink JR. Reduced cerebellar hemisphere size and its relationship to vermal hypoplasia in autism. Arch Neurol 1989;46:689-94.
15. Castelli F, Happè F, Frith U, Frith C. Movement and mind: a functional imaging study of perception and interpretation of complex intentional movement patterns. Neuroimage 2000;12:314-25.
16. Luna B, Minshew NJ, Garver KE, Lazar NA, Thulborn KR, Eddy WF et al. Neocortical system abnormalities in autism: an fMRI study of spatial working memory. Neurology 2002;59:834-40.
17. Kemper TL, Bauman ML. Neuropathology of infantile autism. J Neuropathol Exp Neurol 1998;57:645-52.
18. Haznedar MM, Buchsbaum MS, Wei TC, Hof PR, Cartwright C, Bienstok CA et al. Limbic circuitry in patients with autism spectrum disorders studied with positron emission tomography and magnetic resonance imaging. Am J Psychiatry 2000;157:1994-2001.
19. Pierce K, Muller RA, Ambrose J, Allen G, Courchesne E. Face processing occurs outside the fusiform "face area" in autism: evidence from functional MRI. Brain 2001;124:2059-73.
20. Cook EH, Leventhal BL. The serotonin system in autism. Curr Opin Pediatr 1996;8:348-54.
21. Leventhal BL, Cook EH Jr, Morford M, Ravitz A, Fredman DX. Relationships of whole blood serotonin and plasma norepinephrine within families. J Autism Dev Disord 1990;20:499-511.
22. Chugani DC, Muzik O, Rothermel R, Behen M, Chakraborty P, Mangner T et al. Altered serotonin synthesis in the dentato thalamocortical pathway in autistic boys. Ann Neurol 1997;42:666-9.
23. Martineau J, Barthelemy C, Jouve J, Lelord G. Monoamines (serotonin and catecholamines) and their derivatives in infantile autism: age-related changes and drug effects. Dev Med Child Neurol 1992;34:593-603.
24. Martineau J, Herault J, Petit E, Guerin P, Hameury L, Perrot A et al. Cathecolaminergic metabolism and autism. Dev Med Child Neurol 1994;36:688-97.
25. Chess S, Korn SJ, Fernandez PB. Psychiatric disorders of children with congenital rubella. New York, NY: Brunner/Mazel; 1971.
26. Stubbs EG, Ash E, Williams CP. Autism and congenital cytomegalovirus. J Autism Dev Disord 1984;14:183-9.
27. Gillberg IC. Autistic syndrome with onset at age 31 years: herpes encephalitis as a possible model for childhood autism. Dev Med Child Neurol 1991;33: 920-4.
28. Fonbonne E. The epidemiology of autism: a review. Psychol Med 1999;29:769-86.
29. Aldred S, Moore K, Fitzgerald M, Waring R. Plasma amino acid levels in children with autism and their families. J Autism Dev Disord 2003;33:93-7.
30. Baieli S, Pavone L, Meli C, Fiumara A. Autism and phenylketonuria. J Autism Dev Disord 2003;33:201-4.
31. Page T, Coleman M. Purine metabolism abnormalities in a hyperuricosuric subclass of autism. Biochim Biophys Acta 2000;1500:291-6.
32. Coleman M, Blass JP. Autism and lactic acidosis. J Autism Dev Disord 1985;15:1-8.
33. Schopler K, Reichler R. Deviellis R, Daly K. Towards objective classification of childhood autism: Childhood Autism Rating Scale (CARS). J Autism Dev Disord 1980;10:91-103.
34. Griffiths R. The abilities of young children. High Wycombe. UK: The Test Agency; 1970.
35. Wechsler D. Scala di intelligent Wechsler a livello prescolare e di scuola elementare. Firenze: Edizioni Organizzazioni Speciali; 1996.
36. Wechsler D. Scala di intelligenza Wechsler per bambini riveduta. Firenze: Edizioni Organizzazioni Speciali; 1986.
37. Bauman ML. Microscopic neuroanatomic abnormalities in autism. Pediatrics 1991;87:791-6.
38. Gillberg C, Coleman M. Autism and medical disorders: a review of the literature. Dev Med Child Neurol 1996;38:191-202.
39. Gillberg C, Coleman M. The biology of the autistic syndromes. 3rd ed. Oxford: Mac Keith Press: 2000.
40. Rogers SJ, Wehener DE, Hagerman R. The behavioral phenotype in fragile X: symptoms of autism in very young children with fragile X syndrome, idiophatic autism, and other developmental disorders. J Dev Behav Pediatr 2001;22:409-17.
41. Croonenberghs J, Delmeire L, Verkerk R, Lin AH, Meskal A, Neels H et al. Peripheral markers of serotonergic and noradrenergic function in post-pubertal, (Caucasian males with autistic disorder. Neuropsychopharmacol 2000;22:275-83.
42. Damasio H, Maurer RG, Damasio AR, Chui HC. Computerised tomographic scan findings in patients with autistic behaviour. Arch Neurol 1980;37:504-10.
43. Zilbovicius M, Garreau B, Tzourio N, Mazoyer B, Bruck B, Martinot JL et al. Regional blood flow in autism: a SPECT study. Am J Psychiatry 1992;149:924-30.
44. Courchesne E, Press GA, Yeung-Courchesne R. Parietal lobe abnormalities detected on magnetic resonance of patients with infantile autism. Am J Roentgenology 1993;160:387-93.
45. Tuchman R, Rapin I. Regression in pervasive developmental disorders: seizures and epileptiform electroencephalogram correlates. Pediatrics 1997;99: 560-6.
46. Kawasaki Y, Yokota K, Shinomiya M, Shimizu Y, Niwa S. Brief report: electroencephalographic paroxysmal activities in the frontal area emerged in middle childhood and during adolescence in a follow-up study of autism. J Autism Dev Disord 1997;27:605-20.
47. Verbaten MN, Roelogs JW, Van Engeland H, Kenemans JK, Slangen JL. Abnormal visual event-related potentials of autistic children. J Autism Dev Disord 1991;21: 449-70.
48. Kemner C, Verbaten MN, Cuperus JM, Camfferman G, van Engeland H. Auditory event related brain potentials in autistics children and three different control group. Biol Psychiatry 1995;38:150-65.
49. Herault J, Martineau J, Cherpi C, Perrot A, Barthelemy C, Lelord G et al. Serotonin and autism: biochemical and molecular biology features. Psychiatry Res 1996;65:33-43.
50. Shattock P. Some implications of basic physiological research for the behaviour and treatment of people with autism. In: Conference Proceedings Experimental Psychology and the Autistic syndrome. College St Hilde and St Bede, University Durham; 1990. p. 275-85.
51. Wakefield AJ, Murch SH, Anthony A, Linnel J, Casson DM, Malik M et al. Ileal-lymphoyd-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children. Lancet 1998;351:637-41.
52. Lombard J. Autism: a mitochondrial disorder? Med Hypotheses 1998;50:497-500.
53. Chugani DC, Sundram BS, Behen M, Lee ML, Moore GJ. Evidence of altered energy metabolism in autistic children. Prog Neuropsychopharmacol Biol Psychiatry 1999;23:635-41.