Treatment with continuous intrasynovial antimicrobial infusion for septic synovitis in horses: 31 Cases (2000-2003)

Journal of the American Veterinary Medical Association

Volumn 228, Issue 12, 2006, Pages 1922-1929

  Lescun, Timothy B ^a   Vasey, James R ^b   Ward, Michael P ^a,c   Adams, Stephen B ^a  

^a PURDUE UNIVERSITY   (United States)

^b Australia   (Australia)

^c TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; ANTIBIOTIC AGENT; GENTAMICIN; TICARCILLIN;

ANIMAL DISEASE; ANTIMICROBIAL THERAPY; ARTICLE; CATHETER; CLINICAL FEATURE; DISEASE ASSOCIATION; LONG TERM CARE; NONHUMAN; OSTEOMYELITIS; RETROSPECTIVE STUDY; SEPSIS; SEPTIC SYNOVITIS; SYNOVITIS; TREATMENT OUTCOME;

ANIMALS; ANIMALS, NEWBORN; ANTI-BACTERIAL AGENTS; FEMALE; HORSE DISEASES; HORSES; INFUSION PUMPS; INFUSIONS, INTRALESIONAL; MALE; RETROSPECTIVE STUDIES; SYNOVIAL MEMBRANE; SYNOVITIS; TREATMENT OUTCOME;

ANIMALIA; EQUIDAE;

EID: 33745013644     PISSN: 00031488     EISSN: None     Source Type: Journal    
DOI: 10.2460/javma.228.12.1922     Document Type: Article

References (32)

1. Schneider RK, Bramlage LR, Moore RM, et al. A retrospective study of 192 horses affected with septic arthritis/tenosynovitis. Equine Vet 1992;24:436-442.
2. Hague BA, Carter GK. Diseases of multiple bones and joints; inflammatory, infectious, and immune diseases. In: Colahan PT, Mayhew IG, Merritt AM, et al, eds. Equine medicine and surgery. 5th ed. St Louis: Mosby Inc, 1999;1447-1454.
3. Schneider RK, Bramlage LR, Mecklenburg LM, et al. Open drainage, intra-articular and systemic antibiotics in the treatment of septic arthritis/tenosynovitis in horses. Equine Vet J 1992;24:443-449.
4. Steel CM, Hunt AR, Adams PL, et al. Factors associated with prognosis for survival and athletic use in foals with septic arthritis: 93 cases (1987-1994). J Am Vet Med Assoc 1999;215:973-977.
5. Honnas CM, Schumacher J, Cohen ND, et al. Septic tenosynovitis in horses: 25 cases (1983-1989). J Am Vet Med Assoc 1991;199:1616-1622.
6. Vatistas NJ, Pascoe JR, Wright IM, et al. Infection of the intertubercular bursa in horses: four cases (1978-1991). J Am Vet Med Assoc 1996;208:1434-1437.
7. Wright IM, Phillips TJ, Walmsley JP. Endoscopy of the navicular bursa: a new technique for the treatment of contaminated and septic bursae. Equine Vet J 1999;31:5-11.
8. Bertone AL. Infectious arthritis. In: McIlwraith CW, Trotter GW, eds. Joint disease in the horse. Philadelphia: WB Saunders Co, 1996;397-409.
9. Lloyd KC, Stover SM, Pascoe JR, et al. Synovial fluid pH, cytologic characteristics, and gentamicin concentration after intraarticular administration of the drug in an experimental model of infectious arthritis in horses. Am J Vet Res 1990;51:1363-1369.
10. Whitehair KJ, Adams SB, Parker JE, et al. Regional limb perfusion with antibiotics in three horses. Vet Surg 1992;21:286-292.
11. Palmer SE, Hogan PM. How to perform regional limb perfusion in the standing horse, in Proceedings. 45th Annu Conv Am Assoc Equine Pract 1999;124-127.
12. Bertone AL. Update on infectious arthritis in horses. Equine Vet Educ 1999;11:143-152.
13. Summerhays GE. Treatment of traumatically induced synovial sepsis in horses with gentamicin-impregnated collagen sponges. Vet Rec 2000;147:184-188.
14. Lescun TB, Adams SB, Wu CC, et al. Continuous infusion of gentamicin into the tarsocrural joint of horses. Am J Vet Res 2000;61:407-412.
15. Moore RD, Lietman PS, Smith CR. Clinical response to aminoglycoside therapy: importance of the ratio of peak concentration to minimal inhibitory concentration. J Infect Dis 1987;155:93-99.
16. Swanson TD. Guidelines for veterinary services and judging of endurance and competitive trail rides. In: Guide for veterinary service and judging of equestrian events. Lexington, Ky: American Association of Equine Practitioners, 1991;1-26.
17. Adams SB, Lescun TB. How to treat septic joints with constant intra-articular infusion of gentamicin or amikacin, in Proceedings. 46th Annu Conv Am Assoc Equine Pract 2000;188-192.
18. Moore RM, Schneider RK, Kowalski J, et al. Antimicrobial susceptibility of bacterial isolates from 233 horses with musculoskeletal infection during 1979-1989. Equine Vet J 1992;24:450-456.
19. Schurman DJ, Kajiyama G. Antibiotic absorption from infected and normal joints using a rabbit knee joint model. J Orthop Res 1985;3:185-188.
20. Murphey ED, Santschi EM, Papich MG. Regional intravenous perfusion of the distal limb of horses with amikacin sulfate. J Vet Pharmacol Ther 1999;22:68-71.
21. Wright IM, Smith MR, Humphrey DJ, et al. Endoscopic surgery in the treatment of contaminated and infected synovial cavities. Equine Vet J 2003;35:613-619.
22. Gibson KT, McIlwraith CW, Turner AS, et al. Open joint injuries in horses: 58 cases (1980-1986). J Am Vet Med Assoc 1989;194:398-404.
23. Lescun TB, Adams SB, Wu CC, et al. Effects of continuous intra-articular infusion of gentamicin on synovial membrane and articular cartilage in the tarsocrural joint of horses. Am J Vet Res 2002;63:683-687.
24. Lloyd KC, Stover SM, Pascoe JR, et al. Effect of gentamicin sulfate and sodium bicarbonate on the synovium of clinically normal equine antebrachiocarpal joints. Am J Vet Res 1988;49:650-657.
25. von Eiff C, Jansen B, Kohnen W, et al. Infections associated with medical devices: pathogenesis, management and prophylaxis. Drugs 2005;65:179-214.
26. Bertone AL, McIlwraith CW, Jones RL, et al. Comparison of various treatments for experimentally induced equine infectious arthritis. Am J Vet Res 1987;48:519-529.
27. Gupta MN, Sturrock RD, Field M. Prospective comparative study of patients with culture proven and high suspicion of adult onset septic arthritis. Ann Rheum Dis 2003;62:327-331.
28. Madison JB, Sommer M, Spencer PA. Relations among synovial membrane histopathologic findings, synovial fluid cytologic findings, and bacterial culture results in horses with suspected infectious arthritis: 64 cases (1979-1987). J Am Vet Med Assoc 1991;198:1655-1661.
29. Adamson PJ, Wilson WD, Hirsh DC, et al. Susceptibility of equine bacterial isolates to antimicrobial agents. Am J Vet Res 1985;46:447-450.
30. McCarthy HE, Singer ER, Davies MM. The effect of sodium heparin on equine articular cartilage. Vet J 2001;162:73-79.
31. Hirsh DC, Jang SS. Antimicrobic susceptibility of bacterial pathogens from horses. Vet Clin North Am Equine Pract 1987;3:181-190.
32. Meijer MC, van Weeren PR, Rijkenhuizen AB. Clinical experiences of treating septic arthritis in the equine by repeated joint lavage: a series of 39 cases. J Vet Med A Physiol Pathol Clin Med 2000;47:351-365.