The brain tissue response to biodegradable poly(methylidene malonate 2.1.2)-based microspheres in the rat

Biomaterials

Volumn 27, Issue 28, 2006, Pages 4963-4974

  Fournier, Elvire ^a   Passirani, Catherine ^a   Colin, Nathalie ^b   Sagodira, Serge ^b   Menei, Philippe ^c   Benoit, Jean Pierre ^a   Montero Menei, Claudia N ^a  

^a INSERM   (France)

^b HALISOL   (France)

^c ANGERS UNIVERSITY HOSPITAL   (France)

Author keywords

5 fluorouracil; Biocompatibility; Biodegradation; Microspheres; Poly(methylidene malonate 2.1.2); Rat brain

Indexed keywords

BIOCOMPATIBILITY; BIODEGRADATION; BIODIVERSITY; BRAIN; FREEZING; HISTOLOGY; IMMUNOLOGY; SCANNING ELECTRON MICROSCOPY;

5-FLUOROURACIL; IMMUNOHISTOLOGICAL EVALUATION; MICROSPHERES; POLY(METHYLIDENE MALONATE 2.1.2); RAT BRAIN;

TISSUE;

CARBOXYMETHYLCELLULOSE; FLUOROURACIL; GLIAL FIBRILLARY ACIDIC PROTEIN; MICROSPHERE; POLY(METHYLIDENE MALONATE); POLYMER; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; BIODEGRADABILITY; BRAIN ATROPHY; BRAIN DAMAGE; CELL LOSS; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; EMULSION; FEMALE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INFLAMMATION; MACROPHAGE; MICROGLIA; NONHUMAN; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; STEREOTAXIC SURGERY;

ABSORBABLE IMPLANTS; ANIMALS; BIOCOMPATIBLE MATERIALS; BIODEGRADATION, ENVIRONMENTAL; BRAIN; BRAIN CHEMISTRY; DRUG IMPLANTS; FEMALE; FLUOROURACIL; GLIAL FIBRILLARY ACIDIC PROTEIN; IMMUNOHISTOCHEMISTRY; MALONATES; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; MOLECULAR STRUCTURE; POLYETHYLENES; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

ANIMALIA;

EID: 33745004876     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2006.04.045     Document Type: Article

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