Reduction of Shp-2 expression by small interfering RNA reduces murine embryonic stem cell-derived in vitro hematopoietic differentiation

Stem Cells

Volumn 24, Issue 3, 2006, Pages 587-594

  Zou, Gang Ming ^a   Chan, Rebecca J ^a   Shelley, W Christopher ^a   Yoder, Mervin C ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Embryonic stem cell; Hemangioblast; RNA interference; Shp 2; Small interfering RNA

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; BASIC FIBROBLAST GROWTH FACTOR RECEPTOR; MUTANT PROTEIN; PROTEIN TYROSINE PHOSPHATASE SHP 2; SMALL INTERFERING RNA; PROTEIN TYROSINE PHOSPHATASE; SIGNAL PEPTIDE; SRC HOMOLOGY 2 (SH2) DOMAIN CONTAINING PHOSPHATASES; SRC HOMOLOGY-2 (SH2) DOMAIN-CONTAINING PHOSPHATASES;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL MATURATION; CONTROLLED STUDY; DNA MODIFICATION; EMBRYO; EMBRYONIC STEM CELL; GENE SILENCING; GENETIC TRANSFECTION; HEMANGIOBLAST; HEMATOPOIESIS; HEMATOPOIETIC CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS INHIBITION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; PHYSIOLOGY; STEM CELL;

MURINAE;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEMATOPOIESIS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; PROTEIN-TYROSINE-PHOSPHATASE; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STEM CELLS;

EID: 33744997678     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2005-0272     Document Type: Article

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