Renal stem cells in recovery from acute kidney injury

Minerva Urologica e Nefrologica

Volumn 58, Issue 1, 2006, Pages 13-21

  Humphreys, B D ^a,b   Duffield, J D ^a   Bonventre, J V ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD INSTITUTES OF MEDICINE   (United States)

Author keywords

Kidney failure; Renal injuries; Stem cells

Indexed keywords

BIOCHEMICAL MARKER;

ACUTE KIDNEY FAILURE; CELL DAMAGE; CELL LABELING; CELL PROLIFERATION; CELL REGENERATION; CELL STRUCTURE; CONVALESCENCE; EXPERIMENTAL MODEL; GLOMERULUS BASEMENT MEMBRANE; HEMATOPOIETIC STEM CELL; KIDNEY CELL; KIDNEY INJURY; KIDNEY TUBULE CELL; KIDNEY TUBULE EPITHELIUM; NONHUMAN; REVIEW; STEM CELL; TISSUE REPAIR;

BONE MARROW TRANSPLANTATION; HUMANS; KIDNEY; KIDNEY FAILURE, ACUTE; REGENERATION; STEM CELL TRANSPLANTATION;

EID: 33744983745     PISSN: 03932249     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (38)

1. Osawa M, Hanada K, Hamada H, Nakauchi H. Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science 1996;273:242-5.
2. Morrison SJ, Weissman IL. The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype. Immunity 1994;1:661-73.
3. Reynolds BA, Weiss S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 1992;255:1707-10.
4. Reynolds BA, Weiss S. Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell. Dev Biol 1996;175:1-13.
5. Kim CF, Jackson EL, Woolfenden AE, Lawrence S, Babar I, Vogel S et al. Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell 2005;121:823-35.
6. Tumbar T, Guasch G, Greco V, Blanpain C, Lowry WE, Rendl M et al. Defining the epithelial stem cell niche in skin. Science 2004;303:359-63.
7. Cantley LG. Adult stem cells in the repair of the injured renal tubule. Nat Clin Pract Nephrol 2005;1:22-32.
8. Lin F. Stem cells in kidney regeneration following acute renal injury. Pediatr Res 2006;59 (4 Pt 2):74R-8.
9. Brodie JC, Humes HD. Stem cell approaches for the treatment of renal failure. Pharmacol Rev 2005;57:299-313.
10. Witzgall R, Brown D, Schwarz C, Bonventre JV. Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells. J Clin Invest 1994;93:2175-88.
11. Villanueva S, Cespedes C, Vio CP. Ischemic acute renal failure induces the expression of a wide range of nephrogenic proteins. Am J Physiol Regul Integr Comp Physiol 2006;290:R861-70.
12. Lin F, Moran A, Igarashi P. Intrarenal cells, not bone marrow-derived cells, are the major source for regeneration in postischemic kidney. J Clin Invest 2005;115:1756-64.
13. Bonventre JV. Dedifferentiation and proliferation of surviving epithelial cells in acute renal failure. J Am Soc Nephrol 2003;14 Suppl 1:S55-61.
14. Thadhani R, Pascual M, Bonventre JV. Acute renal failure. N Engl J Med 1996;334:1448-60.
15. Abbate M, Brown D, Bonventre JV. Expression of NCAM recapitulates tubulogenic development in kidneys recovering from acute ischemia. Am J Physiol 1999;277(3 Pt 2):F454-63.
16. Duffield JS, Park KM, Hsiao LL, Kelley VR, Scadden DT, Ichimura T et al. Restoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cells. J Clin Invest 2005;115:1743-55.
17. Bonventre JV. Molecular response to cytotoxic injury: role of inflammation, MAP kinases, and endoplasmic reticulum stress response. Semin Nephrol 2003;23:439-48.
18. Schena FP. Role of growth factors in acute renal failure. Kidney Int Suppl 1998;66:S11-5.
19. Krause DS, Theise ND, Collector MI, Henegariu O, Hwang S, Gardner R et al. Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell. Cell 2001;105:369-77.
20. Lagasse E, Connors H, Al-Dhalimy M, Reitsma M, Dohse M, Osborne L et al. Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nat Med 2000;6:1229-34.
21. Herzog EL, Chai L, Krause DS. Plasticity of marrow-derived stem cells. Blood 2003;102:3483-93.
22. Poulsom R, Forbes SJ, Hodivala-Dilke K, Ryan E, Wyles S, Navaratnarasah S et al. Bone marrow contributes to renal parenchymal turnover and regeneration. J Pathol 2001;195:229-35.
23. Kale S, Karihaloo A, Clark PR, Kashgarian M, Krause DS, Cantley LG. Bone marrow stem cells contribute to repair of the ischemically injured renal tubule. J Clin Invest 2003;112:42-9.
24. Duffield JS, Bonventre JV. Kidney tubular epithelium is restored without replacement with bone marrow-derived cells during repair after ischemic injury. Kidney Int 2005;68:1956-61.
25. Togel F, Hu Z, Weiss K, Isaac J, Lange C, Westenfelder C. Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms. Am J Physiol Renal Physiol 2005;289:F31-42.
26. Lin F, Cordes K, Li L, Hood L, Couser WG, Shankland SJ et al. Hematopoietic stem cells contribute to the regeneration of renal tubules after renal ischemia-reperfusion injury in mice. J Am Soc Nephrol 2003;14:1188-99.
27. Vogetseder A, Karadeniz A, Kaissling B, Le Hir M. Tubular cell proliferation in the healthy rat kidney. Histochem Cell Biol 2005;124:97-104.
28. Oliver JA, Maarouf O, Cheema FH, Martens TP, Al-Awqati Q. The renal papilla is a niche for adult kidney stem cells. J Clin Invest 2004;114:795-804.
29. Burns TC, Ortiz-Gonzalez XR, Gutierrez-Perez M, Keene CD, Sharda R, Demorest ZL et al. Thymidine analogs are transferred from pre-labeled donor to host cells in the central nervous system after transplantation: a word of caution. Stem Cells 2006;24:1121-7.
30. Kuan CY, Schloemer AJ, Lu A, Burns KA, Weng WL, Williams MT et al. Hypoxia-ischemia induces DNA synthesis without cell proliferation in dying neurons in adult rodent brain. J Neurosci 2004;24:10763-72.
31. Maeshima A, Yamashita S, Nojima Y. Identification of renal progenitor-like tubular cells that participate in the regeneration processes of the kidney. J Am Soc Nephrol 2003;14:3138-46.
32. Kitamura S, Yamasaki Y, Kinomura M, Sugaya T, Sugiyama H, Maeshima Y et al. Establishment and characterization of renal progenitor like cells from S3 segment of nephron in rat adult kidney. FASEB J 2005;19:1789-97.
33. Abrahamson DR, Steenhard BM. Renal therapy by stem cells: outsource or in-house? J Am Soc Nephrol 2006;17:2-14.
34. Challen GA, Martinez G, Davis MJ, Taylor DF, Crowe M, Teasdale RD et al. Identifying the molecular phenotype of renal progenitor cells. J Am Soc Nephrol 2004;15:2344-57.
35. Herzlinger D, Koseki C, Mikawa T, al-Awqati Q. Metanephric mesenchyme contains multipotent stem cells whose fate is restricted after induction. Development 1992;114:565-72.
36. Schmidt-Ott KM, Yang J, Chen X, Wang H, Paragas N, Mori K et al. Novel regulators of kidney development from the tips of the ureteric bud. J Am Soc Nephrol 2005;16:1993-2002.
37. McMahon A. Patterning of the mammalian kidney. Kidney Int 2005;68:1962-72.
38. Challen GA, Little MH. A side order of stem cells: the SP phenotype. Stem Cells 2006;24:3-12.