Evidence for assembly of small multidrug resistance proteins by a "two-faced" transmembrane helix

Journal of Biological Chemistry

Volumn 281, Issue 22, 2006, Pages 15546-15553

  Rath, Arianna ^a,b   Melnyk, Roman A ^a,b,c   Deber, Charles M ^a,b  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; CYTOLOGY; ENERGY TRANSFER; MATHEMATICAL MODELS; OLIGOMERS; PROTEINS; TOXIC MATERIALS;

MULTIDRUG RESISTANCE PROTEINS; OLIGOMERIZATION; TOXICANTS;

CELL MEMBRANES;

BACTERIAL PROTEIN; DODECYL SULFATE SODIUM; HELIX LOOP HELIX PROTEIN; MEMBRANE PROTEIN; MULTIDRUG RESISTANCE PROTEIN; PERFLUOROOCTANOIC ACID; PROTEIN HSMR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; ENERGY TRANSFER; HALOBACTERIUM SALINARUM; MATHEMATICAL MODEL; MOLECULAR MODEL; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY;

AMINO ACID SEQUENCE; ARCHAEAL PROTEINS; CIRCULAR DICHROISM; DIMERIZATION; DRUG RESISTANCE, MULTIPLE; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENES, ARCHAEAL; HALOBACTERIUM SALINARUM; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MULTIPROTEIN COMPLEXES; MUTAGENESIS; PROTEIN FOLDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY;

BACTERIA (MICROORGANISMS); HALOBACTERIUM SALINARUM;

EID: 33744965940     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M600434200     Document Type: Article

References (36)

1. Walsh, C. (2000) Nature 406, 775-781
2. Nikaido, H. (1994) Science 264, 382-388
3. Ninio, S., Rotem, D., and Schuldiner, S. (2001) J. Biol. Chem. 276, 48250-48256
4. Paulsen, I. T., Skurray, R. A., Tam, R., Saier, M. H., Jr., Turner, R. J., Weiner, J. H., Goldberg, E. B., and Grinius, L. L. (1996) Mol. Microbiol. 19, 1167-1175
5. Ubarretxena-Belandia, I., and Tate, C. G. (2004) FEBS Lett. 564, 234-238
6. Arkin, I. T., Russ, W. P., Lebendiker, M., and Schuldiner, S. (1996) Biochemistry 35, 7233-7238
7. Schwaiger, M., Lebendiker, M., Yerushalmi, H., Coles, M., Groger, A., Schwarz, C., Schuldiner, S., and Kessler, H. (1998) Eur. J. Biochem. 254, 610-619
8. Tate, C. G., Kunji, E. R., Lebendiker, M., and Schuldiner, S. (2001) EMBO J. 20, 77-81
9. Ubarretxena-Belandia, I., Baldwin, J. M., Schuldiner, S., and Tate, C. G. (2003) EMBO J. 22, 6175-6181
10. Tate, C. G., Ubarretxena-Belandia, I., and Baldwin, J. M. (2003) J. Mol. Biol. 332, 229-242
11. Ma, C., and Chang, G. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 2852-2857
12. Pornillos, O., Chen, Y. J., Chen, A. P., and Chang, G. (2005) Science 310, 1950-1953
13. Ninio, S., Elbaz, Y., and Schuldiner, S. (2004) FEBS Lett. 562, 193-196
14. Elbaz, Y., Steiner-Mordoch, S., Danieli, T., and Schuldiner, S. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 1519-1524
15. Yerushalmi, H., Lebendiker, M., and Schuldiner, S. (1996) J. Biol. Chem. 271, 31044-31048
16. Popot, J. L., and Engelman, D. M. (1990) Biochemistry 29, 4031-4037
17. Ninio, S., and Schuldiner, S. (2003) J. Biol. Chem. 278, 12000-12005
18. Deber, C. M., Wang, C., Liu, L. P., Prior, A. S., Agrawal, S., Muskat, B. L., and Cuticchia, A. J. (2001) Protein Sci. 10, 212-219
19. Amblard, M., Fehrentz, J. A., Martinez, J., and Subra, G. (2005) Methods Mol. Biol. 298, 3-24
20. Melnyk, R. A., Partridge, A. W., and Deber, C. M. (2001) Biochemistry 40, 11106-11113
21. Therien, A. G., and Deber, C. M. (2002) J. Biol. Chem. 277, 6067-6072
22. Partridge, A. W., Melnyk, R. A., Yang, D., Bowie, J. U., and Deber, C. M. (2003) J. Biol. Chem. 278, 22056-22060
23. Zouzoulas, A., Therien, A. G., Scanzano, R., Deber, C. M., and Blostein, R. (2003) J. Biol. Chem. 278, 40437-40441
24. Ramjeesingh, M., Huan, L. J., Garami, E., and Bear, C. E. (1999) Biochem. J. 342, 119-123
25. Chen, Y. H., Yang, J. T., and Chau, K. H. (1974) Biochemistry 13, 3350-3359
26. Gans, P. J., Lyu, P. C., Manning, M. C., Woody, R. W., and Kallenbach, N. R. (1991) Biopolymers 31, 1605-1614
27. Adair, B. D., and Engelman, D. M. (1994) Biochemistry 33, 5539-5544
28. Wang, C., and Deber, C. M. (2000) J. Biol. Chem. 275, 16155-16159
29. Soskine, M., Steiner-Mordoch, S., and Schuldiner, S. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 12043-12048
30. Muth, T. R., and Schuldiner, S. (2000) EMBO J. 19, 234-240
31. Gratkowski, H., Lear, J. D., and DeGrado, W. F. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 880-885
32. Zhou, F. X., Merianos, H. J., Brunger, A. T., and Engelman, D. M. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 2250-2255
33. Johnson, R. M., Heslop, C. L., and Deber, C. M. (2004) Biochemistry 43, 14361-14369
34. Fleming, K. G., and Engelman, D. M. (2001) Proteins 45, 313-317
35. Liu, Y., Engelman, D. M., and Gerstein, M. (2002) Genome Biol. http://genomebiology. com/2002/3/10/research/0054
36. Gottschalk, K. E., Soskine, M., Schuldiner, S., and Kessler, H. (2004) Biophys. J. 86, 3335-3348