Testing mitochondrial metabolic competence by cytochrome oxidase preferential cytochemistry versus immunoreactivity of subunits I and IV

Rejuvenation Research

Volumn 9, Issue 2, 2006, Pages 215-218

  Fattoretti, Patrizia ^a   Balietti, Marta ^a   Giorgetti, Belinda ^a   Grossi, Yessica ^a   Casoli, Tiziana ^a   Di Stefano, Giuseppina ^a   Bertoni Freddari, Carlo ^a  

^a INRCA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C OXIDASE; CYTOCHROME C OXIDASE SUBUNIT I; CYTOCHROME C OXIDASE SUBUNIT IV; UNCLASSIFIED DRUG;

ADOLESCENT; AGED; ANIMAL CELL; ANIMAL TISSUE; BRAIN REGION; CEREBELLUM; CEREBELLUM GRANULAR LAYER; CONFERENCE PAPER; CYTOCHEMISTRY; DENTATE GYRUS; ENERGY METABOLISM; ENZYME ACTIVITY; ENZYME SUBUNIT; FEMALE; IMMUNOHISTOCHEMISTRY; MITOCHONDRIAL RESPIRATION; NONHUMAN; PRIORITY JOURNAL; RAT;

AGING; ANIMALS; CELL NUCLEUS; CEREBELLUM; ELECTRON TRANSPORT COMPLEX IV; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HIPPOCAMPUS; HISTOCYTOCHEMISTRY; MITOCHONDRIA; NEURONS; RATS; RATS, WISTAR;

ANIMALIA;

EID: 33744962696     PISSN: 15491684     EISSN: None     Source Type: Journal    
DOI: 10.1089/rej.2006.9.215     Document Type: Conference Paper

References (12)

1. Taanman JW. Human cytochrome c oxidase: structure, function, and deficiency. J Bioenerg Biomembr 1997;29:151-163.
2. Dykens JA, Carroll AK, Wright AC, Fleck B. Mitochondrial dysfunction in aging and disease: development of therapeutic strategies. In: RG Cutler, H Rodriguez, eds. Critical Reviews of Oxidative Stress and Aging. Advances in Basic Science, Diagnostics and Intervention. Singapore: World Scientific, 2003: 452-466.
3. Collins TJ, Berridge MJ, Lipp P, Bootman MD. Mitochondria are morphologically and functionally heterogeneous within cells. EMBO J 2002;21:1616-1627.
4. Bertoni-Freddari C, Fattoretti P, Casoli T, Di Stefano G, Solazzi M, Meier-Ruge W. Quantitative cytochemical mapping of mitochondrial enzymes in rat cerebella. Micron 2001;32:405-410.
5. Bertoni-Freddari C, Fattoretti P, Paoloni R, Caselli U, Giorgetti B, Solazzi M. Inverse correlation between mitochondrial size and metabolic competence: a quantitative cytochemical study of cytochrome oxidase activity. Naturwissenschaften 2003;90:68-71.
6. Bertoni-Freddari C, Fattoretti P, Giorgetti B, Spazzafumo L, Solazzi M, Balietti M. Age-related decline in metabolic competence of small and medium-sized synaptic mitochondria. Naturwissenschaften 2005;92:82-85.
7. Hevner M, Wong-Riley MT. Brain cytochrome oxidase: purification, antibody production, and immunohistochemical/histochemical correlations in the CNS. J Neurosci 1989;9:3884-3898.
8. Coggeshall RE, Lekan HA. Methods for determining number of cells and synapses: a case for more uniform standard review. J Comp Neurol 1996;364:6-15.
9. Wong-Riley MTT. Changes in the visual system of monocular sutured or enucleated cats demonstrable with cytochrome oxidase histochemistry. Brain Res 1979;171:11-28.
10. Seligman AM, Karnowsky MJ, Wasserkrug HL, Hanker JS. Nondroplet ultrastructural demonstration of cytochrome oxidase activity with a plymerizing osmiophilic reagent, diaminobenzidine (DAB). J Cell Biol 1968;38:1-14.
11. Verwer RWH, Jansen KA, Sluiter AA, Pool CW, Kamphorst W, Swaab DF. Decreased hippocampal metabolic activity in Alzheimer patients is not reflected in the immunoreactivity of cytochrome oxidase subunits. Exp Neurol 2000;163:440-451.
12. Capaldi RA. Structure and assembly of cytochrome c oxidase. Arch Biochem Biophys 1990;280:252-262.