A mouse model for Stickler's syndrome: Ocular phenotype of mice carrying a targeted heterozygous inactivation of type II (pro)collagen gene (Col2a1)

Experimental Eye Research

Volumn 83, Issue 2, 2006, Pages 297-303

  Kaarniranta, Kai ^a,b   Ihanamäki, Tapio ^c   Sahlman, Janne ^a   Pulkkinen, Hertta ^a   Uusitalo, Hannu ^a   Arita, Machiko ^d   Tammi, Raija ^a   Lammi, Mikko J ^a   Helminen, Heikki J ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^d THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

collagen; hyaluronan; Stickler syndrome

Indexed keywords

COLLAGEN TYPE 2; PROCOLLAGEN;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL VACUOLE; CHOROID; CILIARY BODY; CONTROLLED STUDY; CORNEA; EXTRACELLULAR MATRIX; EYE; GENE INACTIVATION; GENOTYPE; HETEROZYGOTE DETECTION; HISTOLOGY; IMMUNOHISTOCHEMISTRY; IRIS; LENS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RETINA; RETINA DETACHMENT; SCLERA; STAINING; STICKLER SYNDROME; STROMA; TISSUE SECTION; VITREOUS BODY;

AGGRECANS; ANIMALS; COLLAGEN TYPE II; DISEASE MODELS, ANIMAL; EXTRACELLULAR MATRIX PROTEINS; EYE; EYE DISEASES, HEREDITARY; EYE PROTEINS; GENE SILENCING; GENOTYPE; HETEROZYGOTE; HYALURONIC ACID; IMMUNOHISTOCHEMISTRY; LECTINS, C-TYPE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, ELECTRON; OCULAR PHYSIOLOGY; PHENOTYPE; PROTEOCHONDROITIN SULFATES; PROTEOGLYCANS; RETINAL DETACHMENT; SYNDROME;

EID: 33744932444     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2005.11.027     Document Type: Article

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