Expression of Sox9 and type IIA procollagen during ocular development and aging in transgenic Del1 mice with a mutation in the type II collagen gene

European Journal of Ophthalmology

Volumn 12, Issue 6, 2002, Pages 450-458

  Ihanamaki T ^a,b   Saamanen A M ^a   Suominen, J ^a   Pelliniemi, L J ^a   Harley, V ^c   Vuorio, E ^a,d   Salminen, H ^a  

^a TURKU UNIVERSITY HOSPITAL   (Finland)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^d UNIVERSITY OF TURKU   (Finland)

Author keywords

Eye; mRNA; Sox9; Transgenic mouse; Type II collagen

Indexed keywords

COLLAGEN TYPE 2; MESSENGER RNA; PROCOLLAGEN; PROCOLLAGEN TYPE IIA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; HIGH MOBILITY GROUP PROTEIN; PEPTIDE FRAGMENT; PROCOLLAGEN TYPE IIA AMINO TERMINAL PEPTIDE; PROCOLLAGEN TYPE IIA AMINO-TERMINAL PEPTIDE; SOX-9 TRANSCRIPTION FACTOR;

AGING; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EYE DEVELOPMENT; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RIBONUCLEASE PROTECTION ASSAY; TRANSGENIC MOUSE; VITREOUS BODY; ANIMAL; C57BL MOUSE; DBA MOUSE; DOWN REGULATION; ENZYME IMMUNOASSAY; GENETICS; GROWTH, DEVELOPMENT AND AGING; MALE; METABOLISM; MUTATION; PRENATAL DEVELOPMENT; RETINA;

AGING; ANIMALS; COLLAGEN TYPE II; DOWN-REGULATION; HIGH MOBILITY GROUP PROTEINS; IMMUNOENZYME TECHNIQUES; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, TRANSGENIC; MUTATION; PEPTIDE FRAGMENTS; PROCOLLAGEN; RETINA; RNA, MESSENGER; TRANSCRIPTION FACTORS; VITREOUS BODY;

EID: 0142056986     PISSN: 11206721     EISSN: None     Source Type: Journal    
DOI: 10.1177/112067210201200602     Document Type: Article

References (33)

1. Bishop PN. The biochemical structure of mammalian vitreous. Eye 1996; 10: 664-70.
2. Zhu Y, Oganesian A, Keene DR, Sandell LJ, Type IIA procollagen containing the cysteine-rich amino propeptide is deposited in the extracellular matrix of prechondrogenic tissue and binds to TGF-beta1 and BMP-2. J Cell Biol 1999; 144: 1069-80.
3. Reardon A, Sandell L, Jones CJ, McLeod D, Bishop PN. Localization of pN-type IIA procollagen on adult bovine vitreous collagen fibrils. Matrix Biol 2000; 19: 169-73.
4. Ryan MC, Sandell LJ. Differential expression of a cysteine-rich domain in the amino-terminal propeptide of type II (cartilage) procollagen by alternative splicing of mRNA. J Biol Chem 1990; 265: 10334-9.
5. Metsäranta M, Toman D, de Crombrugghe B, Vuorio E. Mouse type II collagen gene. J Biol Chem 1991; 266: 16862-9.
6. Sandell LJ, Morris N, Robbins JR, Goldring MR. Alternatively spliced type II procollagen mRNAs define distinct populations of cells during vertebral development: Differential expression of the amino-propeptide. J Cell Biol 1991; 114: 1307-19.
7. Cheah KSE, Lau ET, Au PKC, Tam PPL. Expression of the mouse α1(II) collagen gene is not restricted to cartilage during development. Development 1991; 111: 945-53.
8. Bishop PN, Crossman MV, McLeod D, Ayad S. Extraction and characterization of tissue forms of collagen types II and IX from bovine vitreous. Biochem J 1994; 299: 497-505.
9. Fitch JM, Gordon MK, Gibney EP, Linsenmayer TF. Analysis of transcriptional isoforms of collagen types IX, II and I in the developing avian cornea by competitive polymerase chain reaction. Dev Dyn 1995; 202: 42-53.
10. Savontaus M, Ihanamäki T, Metsäranta M, Vuorio E, Sandberg-Lall, M. Localization of type II collagen mRNA isoforms in the developing eyes of normal and transgenic mice with a mutation in type II collagen gene. Invest Ophthalmol Vis Sci 1997; 38: 930-42.
11. Sandell LJ, Nalin AM, Reife RA. Alternative splice form of type II procollagen mRNA (IIA) is predominant in skeletal precursors and non-cartilaginous tissues during early mouse development. Dev Dyn 1994; 199: 129-40.
12. Lui VCH, Ng LJ, Nicholls J, Tam PPL, Cheah KSE. Tissue-specific and differential expression of alternatively spliced a1(II) collagen mRNAs in early human embryos. Dev Dyn 1995; 203: 198-211.
13. Du F, Acland GM, Ray J. Cloning and expression of type II collagen mRNA: evaluation as a candidate for canine oculo-skeletal dysplasia. Gene 2000; 255: 307-16.
14. Metsäranta M, Garofalo S, Decker G, Rintala M, de Crombrugghe B, Vuorio E. Chondrodysplasia in transgenic mice harboring a 15 amino acid deletion in the triple helical domain of proα1(II) collagen chain. J Cell Biol 1992; 118: 203-12.
15. Ihanamäki T, Salminen H, Säämänen A-M, Pelliniemi LJ, et al. Age-dependent changes in the expression of matrix components in the mouse eye. Exp Eye Res 2001; 72: 423-31.
16. Lefebvre V, de Crombrugghe B. Toward understanding SOX9 function in chondrocyte differentiation. Matrix Biol 1997; 16: 529-40.
17. Lefebvre V, Huang W, Harley VR, Goodfellow PN, de Crombrugghe B. SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro α1(II) collagen gene. Mol Cell Biol 1997; 17: 2336-46.
18. Ng LJ, Wheatley S, Muscat GE, et al. SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse. Dev Biol 1997; 183: 108-21.
19. Bi W, Deng JM, Zhang Z, Behringer RR, de Crombrugghe B. Sox9 is required for cartilage formation. Nat Genet 1999; 22: 85-9.
20. Mertin S, McDowall SG, Harley VR. The DNA-binding specificity of SOX9 and other SOX proteins. Nucleic Acids Res 1999; 27: 1359-64.
21. McDowall S, Argentaro A, Ranganathan S, et al. Functional and structural studies of wild type SOX9 and mutations causing campomelic dysplasia. J Biol Chem 1999; 274: 24023-30.
22. Chirgwin IM, Przybyla AE, MacDonald RJ, Rutter WJ. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 1979; 18: 5294-9.
23. Sambrook J, Fritsch EF, Maniatis T. Extraction, purification and analysis of mRNA from eukaryotic cells. In: Nolan C, ed. Molecular cloning: A laboratory manual. 2nd ed. Cold Spring Harbor: Cold Spring Harbor Laboratory Press 1989; 7.1-7.87.
24. Salminen H, Vuorio E, Säämänen A-M. Expression of Sox9 and type IIA procollagen during attempted repair of articular cartilage damage in a transgenic mouse model for osteoarthritis. Arthritis Rheum 2001; 44: 947-55.
25. da Silva SM, Hacker A, Harley V, Goodfellow P, Swain A, Lovell-Badge R. Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds. Nat Genet 1996; 14: 62-8.
26. Lefebvre V, Li P, de Crombrugghe B. A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene. EMBO J 1998; 17: 5718-33.
27. Du F, Acland GM, Ray J. Differential splicing of type II procollagen mRNA in canine retina. Anim Biotechnol 1998; 9: 15-20.
28. Kon CH, Occleston NL, Aylward GW, Khaw PT. Expression of vitreous cytokines in proliferative vitreoretinopathy: a prospective study. Invest Ophthalmol Vis Sci 1999; 40: 705-12.
29. Akiba J, Ueno N, Chakrabarti B. Age-related changes in the molecular properties of the vitreous collagen. Curr Eye Res 1993; 12: 951-4.
30. Sinex FM. The role of collagen in aging. In: Gould BS, ed. Treatise on collagen, Biology of collagen, vol. 2. London: Academic Press 1968; 409-48.
31. Ihanamäki T, Salminen H, Säämänen A-M, Sandberg-Lall M, Vuorio E, Pelliniemi LJ. Ultrastructural characterization of developmental and degenerative vitreoretinal changes in the eyes of transgenic mice with a deletion mutation in type II collagen gene. Curr Eye Res 2002; (in press).
32. Maumenee IH. Vitreoretinal degeneration as a sign of generalized connective tissue diseases. Am J Ophthalmol 1979; 88: 432-49.
33. Maumenee IH, Traboulsi EI. The ocular findings in Kniest dysplasia. Am J Ophthalmol 1985; 100: 155-60.