Two modes of action by which Xenopus hairy2b establishes tissue demarcation in the Spemann-Mangold organizer

International Journal of Developmental Biology

Volumn 50, Issue 5, 2006, Pages 463-471

  Murato, Yasuhito ^a,b   Yamaguti, Mami ^a,b   Katamura, Miho ^c   Cho, Ken W Y ^d   Hashimoto, Chikara ^a,b  

^a OSAKA UNIVERSITY   (Japan)

^b JT Biohistory Research Hall ^*  (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Organizer; Pattern formation; WRPW motif; Xenopus; Xhairy2b

Indexed keywords

PEPTIDE; TRANSCRIPTION FACTOR E2A; TRANSCRIPTION FACTOR HES 1;

ARTICLE; DOWN REGULATION; EMBRYO DEVELOPMENT; GENE CONTROL; GENE EXPRESSION; GENE REPRESSION; GENETIC TRANSCRIPTION; MESODERM; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN MOTIF; XENOPUS LAEVIS;

ANIMALS; BASE SEQUENCE; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BODY PATTERNING; DNA, COMPLEMENTARY; EMBRYONIC INDUCTION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; ORGANIZERS, EMBRYONIC; PROTEINS; VARIATION (GENETICS); XENOPUS LAEVIS; XENOPUS PROTEINS;

ANIMALIA; VERTEBRATA;

EID: 33744919563     PISSN: 02146282     EISSN: None     Source Type: Journal    
DOI: 10.1387/ijdb.052106ym     Document Type: Article

References (36)

1. ARTINGER, M., BLITZ, I., INOUE, K., TRAN, U. and CHO, K.W. (1997). Interaction of goosecoid and brachyury in Xenopus mesoderm patterning. Mech Dev 65: 187-96.
2. BAE, S., BESSHO, Y., HOJO, M. and KAGEYAMA, R. (2000). The bHLH gene Hes6, an inhibitor of Hes1, promotes neuronal differentiation. Development 127: 2933-43.
3. BLITZ, I.L. and CHO, K.W. (1995). Anterior neurectoderm is progressively induced during gastrulation: the role of the Xenopus homeobox gene orthodenticle. Development 121: 993-1004.
4. COPELAND, J.W., NASIADKA, A., DIETRICH, B.H. and KRAUSE, H.M. (1996). Patterning of the Drosophila embryo by a homeodomain-deleted Ftz polypeptide. Nature 379: 162-5.
5. DAVIS, R.L. and TURNER, D.L. (2001). Vertebrate hairy and Enhancer of split related proteins: transcriptional repressors regulating cellular differentiation and embryonic patterning. Oncogene 20: 8342-57.
6. FISHER, A. and CAUDY, M. (1998). The function of hairy-related bHLH repressor proteins in cell fate decisions. Bioessays 20: 298-306.
7. GAWANTKA, V., DELIUS, H., HIRSCHFELD, K., BLUMENSTOCK, C. and NIEHRS, C. (1995). Antagonizing the Spemann organizer: role of the homeobox gene Xvent-1. EMBO J 14: 6268-79.
8. GIAGTZOGLOU, N., ALIFRAGIS, P., KOUMBANAKIS, K.A. and DELIDAKIS, C. (2003). Two modes of recruitment of E(spl) repressors onto target genes. Development 130: 259-70.
9. GLINKA, A., WU, W., DELIUS, H., MONAGHAN, A.P., BLUMENSTOCK, C. and NIEHRS, C. (1998). Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature 391: 357-62.
10. HARLAND, R. and GERHART, J. (1997). Formation and function of Spemann's organizer. Annu Rev Cell Dev Biol 13: 611-67.
11. HARLAND, R.M. (1991). In situ hybridization: an improved whole-mount method for Xenopus embryos. Methods Cell Biol 36: 685-95.
12. HAWLEY, S.H., WUNNENBERG-STAPLETON, K., HASHIMOTO, C., LAURENT, M.N., WATABE, T., BLUMBERG, B.W. and CHO, K.W. (1995). Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction. Genes Dev 9: 2923-35.
13. HEMMATI-BRIVANLOU, A., KELLY, O.G. and MELTON, D.A. (1994). Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity. Cell 77: 283-95.
14. IEMURA, S., YAMAMOTO, T.S., TAKAGI, C., UCHIYAMA, H., NATSUME, T., SHIMASAKI, S., SUGINO, H. and UENO, N. (1998). Direct binding of follistatin to a complex of bone-morphogenetic protein and its receptor inhibits ventral and epidermal cell fates in early Xenopus embryo. Proc Natl Acad Sci USA 95: 9337-42.
15. KUROIWA, A., HAFEN, E. and GEHRING, W.J. (1984). Cloning and transcriptional analysis of the segmentation gene fushi tarazu of Drosophila. Cell 37: 825-31.
16. LEYNS, L., BOUWMEESTER, T., KIM, S.H., PICCOLO, S. and DE ROBERTIS, E.M. (1997). Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer. Cell 88: 747-56.
17. LÓPEZ, S.L., ROSATO-SIRI, M.V., FRANCO, P.G., PAGANELLI, A.R. and CARRASCO, A.E. (2005). The Notch-target gene hairy2a impedes the involution of notochordal cells by promoting floor plate fates in Xenopus embryos. Development 132: 1035-46.
18. MCLARREN, K.W., LO, R., GRBAVEC, D., THIRUNAVUKKARASU, K., KARSENTY, G. and STIFANI, S. (2000). The mammalian basic helix loop helix protein HES-1 binds to and modulates the transactivating function of the runt-related factor Cbfa1. J Biol Chem 275: 530-8.
19. MESSENGER, N.J., KABITSCHKE, C. ANDREWS, R., GRIMMER, D., NUNEZ MIGUEL, R., BLUNDELL, T.L., SMITH, J.C. and WARDLE, F.C. (2005). Functional specificity of the Xenopus T-domain protein Brachyury is conferred by its ability to interact with Smad1. Dev Cell 8: 599-610.
20. MIZUSEKI, K., KISHI, M., MATSUI, M., NAKANISHI, S. and SASAI, Y. (1998). Xenopus Zic-related-1 and Sox-2, two factors induced by chordin, have distinct activities in the initiation of neural induction. Development 125: 579-87.
21. MOOS, M., JR., WANG, S. and KRINKS, M. (1995). Anti-dorsalizing morphogenetic protein is a novel TGF-beta homolog expressed in the Spemann organizer. Development 121: 4293-301.
22. NEWMAN, C.S., CHIA, F. and KRIEG, P.A. (1997). The XHex homeobox gene is expressed during development of the vascular endothelium: overexpression leads to an increase in vascular endothelial cell number. Mech Dev 66: 83-93.
23. NIEUWKOOP, P.D. and FABER, J. (1967). Normal table of Xenopus laevis (Daudin). A systematical and chronological survey of the development from the fertilized egg till the end of metamorphosis. North-Holland Pub. Co., Amsterdam.
24. ONICHTCHOUK, D., GAWANTKA, V., DOSCH, R., DELIUS, H., HIRSCHFELD, K., BLUMENSTOCK, C. and NIEHRS, C. (1996). The Xvent-2 homeobox gene is part of the BMP-4 signalling pathway controlling [correction of controling] dorsoventral patterning of Xenopus mesoderm. Development 122: 3045-53.
25. POOLE, S.J., KAUVAR, L.M., DREES, B. and KORNBERG, T. (1985). The engrailed locus of Drosophila: structural analysis of an embryonic transcript. Cell 40: 37-43.
26. SANDER, K. and FAESSLER, P.E. (2001). Introducing the Spemann-Mangold organizer: experiments and insights that generated a key concept in developmental biology. Int. J. Dev. Biol. 45: 1-11.
27. SASAI, Y., LU, B., STEINBEISSER, H., GEISSERT, D., GONT, L.K. and DE ROBERTIS, E.M. (1994). Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes. Cell 79: 779-90.
28. SMITH, J.C., PRICE, B.M., GREEN, J.B., WEIGEL, D. and HERRMANN, B.G. (1991). Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction. Cell 67: 79-87.
29. SUN, Y., NADAL-VICENS, M., MISONO, S., LIN, M.Z., ZUBIAGA, A., HUA, X., FAN, G. and GREENBERG, M.E. (2001). Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms. Cell 104:365-76.
30. SUZUKI, T., KAWASAKI, H., YU, R.T., UEDA, H. and UMESONO, K. (2001). Segmentation gene product Fushi tarazu is an LXXLL motif-dependent coactivator for orphan receptor FTZ-F1. Proc Natl Acad Sci USA 98: 12403-8.
31. TAIRA, M., JAMRICH, M., GOOD, P.J. and DAWID, I.B. (1992). The LIM domain-containing homeo box gene Xlim-1 is expressed specifically in the organizer region of Xenopus gastrula embryos. Genes Dev 6: 356-66.
32. TSUJI, S., CHO, K.W. and HASHIMOTO, C. (2003). Expression pattern of a basic helix-loop-helix transcription factor Xhairy2b during Xenopus laevis development. Dev Genes Evol 213: 407-11.
33. TSUJI, S. and HASHIMOTO, C. (2005). Choice of either beta-catenin or Groucho/TLE as a co-factor for Xtcf-3 determines dorsal-ventral cell fate of diencephalon during Xenopus development. Dev Genes Evol 215: 275-84.
34. WANG, S., KRINKS, M., LIN, K., LUYTEN, F.P. and MOOS, M., JR. (1997). Frzb, a secreted protein expressed in the Spemann organizer, binds and inhibits Wnt-8. Cell 88: 757-66.
35. YAMAGUTI, M., CHO, K.W. and HASHIMOTO, C. (2005). Xenopus hairy2b specifies anterior prechordal mesoderm identity within Spemann's organizer. Dev Dyn 234: 102-13.
36. YOSHIDA, S., MARIKAWA, Y. and SATOH, N. (1996). Posterior end mark, a novel maternal gene encoding a localized factor in the ascidian embryo. Development 122: 2005-12.