Focus on Molecules: Pax-6, the Eye Master

Experimental Eye Research

Volumn 83, Issue 2, 2006, Pages 233-234

  Tsonis, Panagiotis A ^a   Fuentes, Ernesto J ^b  

^a UNIVERSITY OF DAYTON   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

eye development; Pax 6; structure

Indexed keywords

TRANSCRIPTION FACTOR PAX6;

AMINO ACID SEQUENCE; ANOPHTHALMIA; DEVELOPMENTAL GENETICS; EYE DEVELOPMENT; EYE DISEASE; GENE ACTIVATION; GENE FUNCTION; GENE MUTATION; GENE STRUCTURE; HUMAN; MICROPHTHALMIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; SHORT SURVEY;

ANIMALS; DNA; DROSOPHILA; EYE; EYE PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; HUMANS; MODELS, GENETIC; MUTATION; PAIRED BOX TRANSCRIPTION FACTORS; REPRESSOR PROTEINS;

EID: 33744902872     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2005.11.019     Document Type: Short Survey

References (4)

1. Gehring W.J. The genetic control of eye development and its implications for the evolution of the various eye-types. Int. J. Dev. Biol. 46 (2002) 65-73
2. van Heyningen V., and Williamson K.A. PAX6 in sensory development. Hum. Mol. Genet. 11 (2002) 1161-1167
3. Treisman J.E. How to make an eye. Development 131 (2004) 3823-3827
4. Xu H.E., Rould M.A., Xu W., Epstein J.A., Maas R.L., and Pabo C.O. Crystal structure of the human Pax6 paired domain-DNA complex reveals specific roles for the linker region and carboxy-terminal subdomain in DNA binding. Genes Dev. 13 (1999) 1263-1275