An analysis of pediatric blood cultures in the postpneumococcal conjugate vaccine era in a community hospital emergency department

Pediatric Emergency Care

Volumn 22, Issue 5, 2006, Pages 295-300

  Sard, Brian ^a,b,c   Bailey, Mary Christine ^b   Vinci, Robert ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NEWTON WELLESLEY HOSPITAL   (United States)

^c BOSTON MEDICAL CENTER   (United States)

Author keywords

Bacteremia; Blood culture; Fever

Indexed keywords

ANTIBIOTIC AGENT; PNEUMOCOCCUS VACCINE;

BACTEREMIA; BACTERIAL GROWTH; BLOOD CULTURE; BODY TEMPERATURE; COMMUNITY HOSPITAL; CONTROLLED STUDY; EMERGENCY WARD; FEMALE; FEVER; GRAM STAINING; HOSPITAL DISCHARGE; HUMAN; INFANT; INFECTION; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD; PRESCHOOL CHILD; PREVALENCE; REVIEW;

BACTEREMIA; CHILD, PRESCHOOL; COLONY COUNT, MICROBIAL; EMERGENCY SERVICE, HOSPITAL; FALSE POSITIVE REACTIONS; FEMALE; GENTIAN VIOLET; HOSPITALS, COMMUNITY; HUMANS; INCIDENCE; INFANT; INFANT, NEWBORN; LEUKOCYTE COUNT; MALE; MASSACHUSETTS; PHENAZINES; PNEUMOCOCCAL INFECTIONS; PNEUMOCOCCAL VACCINES; RETROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; STREPTOCOCCUS PNEUMONIAE;

EID: 33744796816     PISSN: 07495161     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.pec.0000215137.51909.16     Document Type: Review

References (19)

1. Fleisher GR, Ludwig S. Textbook of Pediatric Emergency Medicine. 4th ed. Philadelphia, Pa: Lippincott Williams & Williams; 2000.
2. Lee GM, Harper MB. Risk of bacteremia for febrile young children in the post-Haemophilus influenzae type b era. Arch Pediatr Adolesc Med. 1998;152:624-628.
3. Soman M. Characteristics and management of febrile young children in a university family practice. J Fam Pract. 1985;21:117-122.
4. Baraff LJ. Management of fever without source in infants and children. Ann Emerg Med. 2000;36:602-614.
5. Baraff LJ, Bass JW, Fleisher GR, et al. Practice guideline for the management of infants and children 0-36 months of age with fever without source. Ann Emerg Med. 1993;22:1198-1210.
6. Alpern ER, Alessandrini EA, Bell LM, et al. Occult bacteremia from a pediatric emergency department: current prevalence, time to detection, and outcome. Pediatrics. 2000;106:505-511.
7. Black S, Shinefield H, Fireman B, et al. Efficacy, safety and immunogenicity of heptavalent pneumococcal conjugate vaccine in children. Northern California Kaiser Permanente Vaccine Study Center Group. Pediatr Infect Dis J. 2000;19(3):187-195.
8. Black S, Shinefield H, Baxter R, et al. Postlicensure surveillance for pneumococcal invasive disease after use of heptavalent pneumococcal conjugate vaccine in Northern California Kaiser Permanente. Pediatr Infect Dis J. 2004;23:485-489.
9. Kaplan SL, Mason EO Jr, Wald ER, et al. Decrease of invasive pneumococcal infections in children among 8 children's hospitals in the United States after the introduction of the 7-valent pneumococcal conjugate vaccine. Pediatrics. 2004;113:443-449.
10. Whitney CG, Farley MM, Hadler J, et al. Decline in Invasive pneumococcal disease after the introduction of protein-polysaccharide conjugate vaccine. N Engl J Med. 2003;348:1737-1746.
11. McGowan JE, Bratton L, Klein JO, et al. Bacteremia in febrile children seen in a "walk-in" pediatric clinic. N Engl J Med. 1973;288:1309-1312.
12. Teele DW, Pelton SI, Grant MJA, et al. Bacteremia in febrile children under 2 years of age: results of blood cultures of 600 consecutive febrile children seen in a "walk-in" clinic. J Pediatr. 1975;87:227-230.
13. Thuler LC, Jenicek M, Turgeon JP, et al. Impact of a false positive blood culture result on the management of febrile children. Pediatr Infect Dis J. 1997;16:846-851.
14. McGowan KL, Foster JA, Coffin SE. Outpatient pediatric blood cultures: time to positivity. Pediatrics. 2000;106:251-255.
15. Kornberg AE, Jain N, Dannenhoffer R. Evaluation of false positive blood cultures: guidelines for early detection of contaminated cultures in febrile children. Pediatr Emerg Care. 1994;10:20-22.
16. Kaplan RL, Harper MB, Baskin MN, et al. Time to detection of positive cultures in 28- to 90-day old febrile infants. Pediatrics. 2000;106(6):e74-e78.
17. Bachur R, Harper MB. Reevaluation of outpatients with Streptococcus pneumoniae bacteremia. Pediatrics. 2000;105:502-509.
18. Stoll ML, Rubin LG. Incidence of occult bacteremia among highly febrile young children in the era of the pneumococcal conjugate vaccine. Arch Pediatr Adolesc Med. 2004;158:671-675.
19. Bandyopadhyay S, Bergholte J, Blackwell CD, et al. Risk of serious bacterial infection in children with fever without source in the post-Haemophilus influenzae era when antibiotics are reserved for culture-proven bacteremia. Arch Pediatr Adolesc Med. 2002;156:512-517.