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Volumn 4, Issue 9, 2006, Pages 1723-1729

The syntheses and properties of tricyclic pyrrolo[2,3-d]pyrimidine analogues of S6-methylthioguanine and O6-methylguanine

(9) Hornillo Araujo, Ana R a Burrell, Adam J M a Aiertza, Miren K a Shibata, Takayuki a Hammond, David M a,c Edmont, Dolorès a,d Adams, Harry a Margison, Geoffrey P b Williams, David M a

a UNIVERSITY OF SHEFFIELD (United Kingdom)

b CHRISTIE HOSPITAL (United Kingdom)

c UNIVERSITY OF MUNICH (Germany)

d UNIVERSITÉ DE MONTPELLIER (France)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTAL STRUCTURE; DNA; OXYGEN; PROTEINS; SOLUTIONS; SYNTHESIS (CHEMICAL);

HUMAN REPAIR PROTEIN; METHYLGUANINE-DNA METHYLTRANSFERASE (MGMT); SUBSTRATE ASSAY;

ORGANIC COMPOUNDS;

6 METHYLTHIOGUANINE; 6-METHYLTHIOGUANINE; DRUG DERIVATIVE; GUANINE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; O (6) METHYLGUANINE; O-(6)-METHYLGUANINE; PYRIMIDINE DERIVATIVE; PYRROLE DERIVATIVE; PYRROLO(2,3 D)PYRIMIDINE; PYRROLO(2,3-D)PYRIMIDINE; TIOGUANINE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME SPECIFICITY; HUMAN; METABOLISM; PH; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; GUANINE; HUMANS; HYDROGEN-ION CONCENTRATION; MOLECULAR STRUCTURE; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; PYRIMIDINES; PYRROLES; SUBSTRATE SPECIFICITY; THIOGUANINE;

EID: 33744789173 PISSN: 14770520 EISSN: None Source Type: Journal
DOI: 10.1039/b516447h Document Type: Article

Times cited : (7)

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