Phase II study of gemcitabine and cisplatin in advanced biliary tract cancer

Journal of Gastroenterology and Hepatology (Australia)

Volumn 21, Issue 6, 2006, Pages 999-1003

  Park, Byung Kyu ^a   Kim, Yoon Jae ^a   Park, Jeong Youp ^a   Bang, Seungmin ^a   Park, Seung Woo ^a   Chung, Jae Bock ^a   Kim, Kyung Sik ^a   Choi, Jin Sub ^a   Lee, Woo Jung ^a   Song, Si Young ^a  

^a Yonsei University College of Medicine   (South Korea)

Author keywords

Biliary tract cancer; Chemotherapy; Cisplatin; Gemcitabine

Indexed keywords

CISPLATIN; GEMCITABINE;

ADULT; AGED; ANEMIA; ARTICLE; BILIARY TRACT CANCER; BLEEDING; CANCER COMBINATION CHEMOTHERAPY; CANCER REGRESSION; CHEMOTHERAPY INDUCED EMESIS; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE COURSE; DRUG FATALITY; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; HEPATOBILIARY SYSTEM; HISTOPATHOLOGY; HUMAN; LEUKOPENIA; MALE; METASTASIS; NAUSEA; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; SEPSIS; SURVIVAL RATE; SURVIVAL TIME; THROMBOCYTOPENIA; WORLD HEALTH ORGANIZATION;

EID: 33744750925     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2006.04230.x     Document Type: Article

References (32)

1. Ahlgren JD. Neoplasms of the hepatobiliary system. In:Calabresi P Schein PS, eds. Medical Oncology 2. New York:McGraw-Hill, 1993 713 39.
2. Groen PC Gores GJ LaRusso NF et al. Biliary tract cancers. N. Engl. J. Med. 1999 341:1368 78.
3. Goderfridus JP Plunkett W. Gemcitabine: status of preclinical study and perspectives for the future clinical applications of this novel nucleoside analog. Semin. Oncol. 1995 22:1 3.
4. Burris HA Moore MJ Andersen J et al. Improvements in survival and clinical benefit with gemcitabine as first line therapy for patients with advanced pancreas cancer: a randomized trial. J. Clin. Oncol. 1997 1:2403 7.
5. Penz M Kornek GV Raderer M et al. Phase II trial of two-weekly gemcitabine in patients with advanced biliary tract cancer Ann. Oncol. 2001 12:183 6.
6. Gebbia V Giuliani F Maiello E et al. Treatment of inoperable and/or metastatic biliary tree carcinomas with single agent gemcitabine or in combination with levofolinic acid and infusional fluorouracil: Results of a multicenter phase II study. J. Clin. Oncol. 2001 19:4089 91.
7. Kanzawa F Saijo N. In vitro interaction between gemcitabine and other anticancer drugs using a novel three-dimensional model. Semin. Oncol. 1997 24 Suppl. S7 8-16.
8. Peters GJ Bergman AM Ruiz van Haperen VW et al. Interaction between cisplatin and gemcitabine in vitro and in vivo. Semin. Oncol. 1995 22:72 9.
9. Bergman AM Ruiz van Haperen VWT Veerman G et al. Synergistic interaction between cisplatin and gemcitabine in vitro. Clin. Cancer Res. 1996 2:521 30.
10. Crino L Scagliotti G Marangolo M et al. Cisplatin-gemcitabine combination in advanced non-small-cell lung cancer: a phase II study. J. Clin. Oncol. 1997 15:297 303.
11. Hitt R Castellano D Hidalgo M et al. Phase II trial of cisplatin and gemcitabine in advanced squamous-cell carcinoma of the head and neck. Ann. Oncol. 1998 9:1347 9.
12. Heinemann V Wilke H Mergenthaler HG et al. Gemcitabine and cisplatin in the treatment of advanced or metastatic pancreatic cancer. Ann. Oncol. 2000 11:1399 403.
13. Sanz-Altamira PM O'Reilly E Stuart KE et al. A phase II trial of irinotecan (CPT-11) for unresectable biliary tree carcinoma. Ann. Oncol. 2001 12:501 4.
14. Okada S Ishii H Nose H et al. A phase II study of cisplatin in patients with biliary tract carcinoma. Oncology 1994 51:515 17.
15. Ducreux M Rougier P Fandi A et al. Effective treatment of advanced biliary tract carcinoma using 5-fluorouracil continuous infusion with cisplatin. Ann. Oncol. 1998 9:653 6.
16. Patt YZ Hassan MM Lozano RD et al. Phase II trial of cisplatin, interferon alpha-2b, doxorubicin, and 5-fluorouracil for biliary tract cancer. Clin. Cancer Res. 2001 7:3375 80.
17. Jones DV Lozano R Hoque A et al. Phase II study of paclitaxel for unresectable biliary tree carcinomas. J. Clin. Oncol. 1996 14:2306 10.
18. Oberfield RA Rossi RL. The role of chemotherapy in the treatment of bile duct cancer. World J. Surg. 1988 12:105 8.
19. Morizane C Okada S Okusaka T et al. Phase II study of cisplatin, epirubicin, and continuous-infusion 5-fluorouracil for advanced biliary tract cancer. Oncology 2003 64:475 6.
20. Falkson G MacIntyre JM Moertel GG. Eastern Cooperative Oncology Group experience with chemotherapy for inoperable gallbladder and bile duct cancer. Cancer 1984 54:965 9.
21. Sanz-Altamira PM Ferrante K Jenkins RL et al. A phase II trial of 5-fluorouracil, leucovorin, and carboplatin in patients with unresectable biliary tree carcinoma. Cancer 1998 82:2321 5.
22. Harvey JH Smith FP Schein PS. 5-fluorouracil, mitomycin, and doxorubicin (FAM) in carcinoma of the biliary tract. J. Clin. Oncol. 1984 2:1245 8.
23. Scheithauer W. Review of gemcitabine in biliary tract carcinoma. Semin. Oncol. 2002 29:40 5.
24. Gallardo JO Rubio B Fodor M et al. A phase II study of gemcitabine in gallbladder carcinoma. Ann. Oncol. 2001 12:1403 6.
25. Knox JJ Hedley D Oza A et al. Gemcitabine concurrent with continuous infusional 5-fluorouracil in advanced biliary cancers: a review of the Princess Margaret Hospital experience. Ann. Oncol. 2004 15:770 4.
26. André T Tournigand C Rosmorduc O et al. Gemcitabine combined with oxaliplatin (GEMOX) in advanced biliary tract adenocarcinoma: a GEMOX study. Ann. Oncol. 2004 15:1339 43.
27. Kornek GV Schuell B Laungle F et al. Mitomycin C in combination with capecitabine or biweekly high-dose gemcitabine in patients with advanced biliary tract cancer: a randomized phage II trial. Ann. Oncol. 2004 15:478 83.
28. Hsu C Shen YC Yang CH et al. Weekly gemcitabine plus 24-h infusion of high dose 5-fluorouracil/leucovorin for locally advanced or metastatic carcinoma of the biliary tract. Br. J. Cancer 2004 90:1715 19.
29. Knox JJ Hedley D Oza A et al. Combining gemcitabine and capecitabine in patients with advanced biliary cancer: a phase II trial. J. Clin. Oncol. 2005 23:2332 8.
30. Malik IA Aziz Z Zaidi SHM et al. Gemcitabine and cisplatin is a highly effective combination chemotherapy in patients with advanced cancer of the gallbladder. Am. J. Clin. Oncol. 2003 26:174 7.
31. Doval DC Sekhon JS Gupta SK et al. A phase II study of gemcitabine and cisplatin in chemotherapy-naïve, unresectable gall bladder cancer. Br. J. Cancer 2004 90:1516 20.
32. Thongprasert S Napapan S Charoentum C et al. Phase II study of gemcitabine and cisplatin as first-line chemotherapy in inoperable biliary tract carcinoma. Ann. Oncol. 2005 16:279 81.