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Volumn 10, Issue 3, 2006, Pages 226-231

Microfluidic cartridges preloaded with nanoliter plugs of reagents: an alternative to 96-well plates for screening

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME; REAGENT;

EID: 33744537288     PISSN: 13675931     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbpa.2006.04.004     Document Type: Review
Times cited : (92)

References (26)
  • 1
    • 4744364544 scopus 로고    scopus 로고
    • Single-molecule spectroscopic methods
    • Haustein E., and Schwille P. Single-molecule spectroscopic methods. Curr Opin Struct Biol 14 (2004) 531-540
    • (2004) Curr Opin Struct Biol , vol.14 , pp. 531-540
    • Haustein, E.1    Schwille, P.2
  • 2
    • 10944231321 scopus 로고    scopus 로고
    • Fundamentals and practice for ultrasensitive laser-induced fluorescence detection in microanalytical systems
    • Johnson M.E., and Landers J.P. Fundamentals and practice for ultrasensitive laser-induced fluorescence detection in microanalytical systems. Electrophoresis 25 (2004) 3513-3527
    • (2004) Electrophoresis , vol.25 , pp. 3513-3527
    • Johnson, M.E.1    Landers, J.P.2
  • 3
    • 33645731679 scopus 로고    scopus 로고
    • Fluorescence fluctuation spectroscopy in reduced detection volumes
    • Blom H., Kastrup L., and Eggeling C. Fluorescence fluctuation spectroscopy in reduced detection volumes. Curr Pharm Biotechnol 7 (2006) 51-66
    • (2006) Curr Pharm Biotechnol , vol.7 , pp. 51-66
    • Blom, H.1    Kastrup, L.2    Eggeling, C.3
  • 4
    • 27844596763 scopus 로고    scopus 로고
    • Fluorescence-based assay formats and signal amplification strategies for DNA microarray analysis
    • Park H.G., Song J.Y., Park K.H., and Kim M.H. Fluorescence-based assay formats and signal amplification strategies for DNA microarray analysis. Chem Eng Sci 61 (2006) 954-965
    • (2006) Chem Eng Sci , vol.61 , pp. 954-965
    • Park, H.G.1    Song, J.Y.2    Park, K.H.3    Kim, M.H.4
  • 6
    • 30144442150 scopus 로고    scopus 로고
    • Mass spectrometers for the analysis of biomolecules
    • Elsevier Academic Press, Inc
    • Baldwin M.A. Mass spectrometers for the analysis of biomolecules. Biological Mass Spectrometry. Methods Enzymol vol 402 (2005), Elsevier Academic Press, Inc 3-48
    • (2005) Biological Mass Spectrometry. Methods Enzymol , vol.402 , pp. 3-48
    • Baldwin, M.A.1
  • 8
    • 20544440319 scopus 로고    scopus 로고
    • Nanoliter homogenous ultra-high throughput screening microarray for lead discoveries and IC50 profiling
    • Ma H., Horiuchi K.Y., Wang Y., Kucharewicz S.A., and Diamond S.L. Nanoliter homogenous ultra-high throughput screening microarray for lead discoveries and IC50 profiling. Assay Drug Dev Technol 3 (2005) 177-187
    • (2005) Assay Drug Dev Technol , vol.3 , pp. 177-187
    • Ma, H.1    Horiuchi, K.Y.2    Wang, Y.3    Kucharewicz, S.A.4    Diamond, S.L.5
  • 9
    • 5144223105 scopus 로고    scopus 로고
    • Systematic investigation of protein phase behavior with a microfluidic formulator
    • Hansen C.L., Sommer M.O.A., and Quake S.R. Systematic investigation of protein phase behavior with a microfluidic formulator. Proc Natl Acad Sci USA 101 (2004) 14431-14436
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 14431-14436
    • Hansen, C.L.1    Sommer, M.O.A.2    Quake, S.R.3
  • 10
    • 32444435330 scopus 로고    scopus 로고
    • Parallel picoliter RT-PCR assays using microfluidics
    • Marcus J.S., Anderson W.F., and Quake S.R. Parallel picoliter RT-PCR assays using microfluidics. Anal Chem 78 (2006) 956-958
    • (2006) Anal Chem , vol.78 , pp. 956-958
    • Marcus, J.S.1    Anderson, W.F.2    Quake, S.R.3
  • 12
    • 0344875161 scopus 로고    scopus 로고
    • Millisecond kinetics on a microfluidic chip using nanoliters of reagents
    • Song H., and Ismagilov R.F. Millisecond kinetics on a microfluidic chip using nanoliters of reagents. J Am Chem Soc 125 (2003) 14613-14619
    • (2003) J Am Chem Soc , vol.125 , pp. 14613-14619
    • Song, H.1    Ismagilov, R.F.2
  • 13
    • 33644654279 scopus 로고    scopus 로고
    • Microgram-scale testing of reaction conditions in solution using nanoliter plugs in microfluidics with detection by MALDI-MS
    • Using prefabricated cartridges to screen and optimize organic reaction conditions is described. Less than one microgram of substrate was used for each reaction, and the optimized conditions were confirmed by isolating the corresponding products in larger-scale reactions.
    • Hatakeyama T., Chen D.L.L., and Ismagilov R.F. Microgram-scale testing of reaction conditions in solution using nanoliter plugs in microfluidics with detection by MALDI-MS. J Am Chem Soc 128 (2006) 2518-2519. Using prefabricated cartridges to screen and optimize organic reaction conditions is described. Less than one microgram of substrate was used for each reaction, and the optimized conditions were confirmed by isolating the corresponding products in larger-scale reactions.
    • (2006) J Am Chem Soc , vol.128 , pp. 2518-2519
    • Hatakeyama, T.1    Chen, D.L.L.2    Ismagilov, R.F.3
  • 14
    • 0043194348 scopus 로고    scopus 로고
    • Screening of protein crystallization conditions on a microfluidic chip using nanoliter-size droplets
    • Zheng B., Roach L.S., and Ismagilov R.F. Screening of protein crystallization conditions on a microfluidic chip using nanoliter-size droplets. J Am Chem Soc 125 (2003) 11170-11171
    • (2003) J Am Chem Soc , vol.125 , pp. 11170-11171
    • Zheng, B.1    Roach, L.S.2    Ismagilov, R.F.3
  • 15
    • 0037450165 scopus 로고    scopus 로고
    • A microfluidic system for controlling reaction networks in time
    • Song H., Tice J.D., and Ismagilov R.F. A microfluidic system for controlling reaction networks in time. Angew Chem Int Ed 42 (2003) 768-772
    • (2003) Angew Chem Int Ed , vol.42 , pp. 768-772
    • Song, H.1    Tice, J.D.2    Ismagilov, R.F.3
  • 16
    • 11844250557 scopus 로고    scopus 로고
    • Reagent-loaded cartridges for valveless and automated fluid delivery in microfluidic devices
    • The authors fabricated cartridges consisted of reagents separated by air bubbles, and used the cartridges to perform immunoassays.
    • Linder V., Sia S.K., and Whitesides G.M. Reagent-loaded cartridges for valveless and automated fluid delivery in microfluidic devices. Anal Chem 77 (2005) 64-71. The authors fabricated cartridges consisted of reagents separated by air bubbles, and used the cartridges to perform immunoassays.
    • (2005) Anal Chem , vol.77 , pp. 64-71
    • Linder, V.1    Sia, S.K.2    Whitesides, G.M.3
  • 17
    • 0242492537 scopus 로고    scopus 로고
    • Formation of droplets and mixing in multiphase microfluidics at low values of the Reynolds and the capillary numbers
    • Tice J.D., Song H., Lyon A.D., and Ismagilov R.F. Formation of droplets and mixing in multiphase microfluidics at low values of the Reynolds and the capillary numbers. Langmuir 19 (2003) 9127-9133
    • (2003) Langmuir , vol.19 , pp. 9127-9133
    • Tice, J.D.1    Song, H.2    Lyon, A.D.3    Ismagilov, R.F.4
  • 18
    • 3342898592 scopus 로고    scopus 로고
    • A droplet-based, composite PDMS/glass capillary microfluidic system for evaluating protein crystallization conditions by microbatch and vapor-diffusion methods with on-chip X-ray diffraction
    • Zheng B., Tice J.D., Roach L.S., and Ismagilov R.F. A droplet-based, composite PDMS/glass capillary microfluidic system for evaluating protein crystallization conditions by microbatch and vapor-diffusion methods with on-chip X-ray diffraction. Angew Chem Int Ed 43 (2004) 2508-2511
    • (2004) Angew Chem Int Ed , vol.43 , pp. 2508-2511
    • Zheng, B.1    Tice, J.D.2    Roach, L.S.3    Ismagilov, R.F.4
  • 19
    • 4344674322 scopus 로고    scopus 로고
    • Multi-step synthesis of nanoparticles performed on millisecond time scale in a microfluidic droplet-based system
    • Shestopalov I., Tice J.D., and Ismagilov R.F. Multi-step synthesis of nanoparticles performed on millisecond time scale in a microfluidic droplet-based system. Lab Chip 4 (2004) 316-321
    • (2004) Lab Chip , vol.4 , pp. 316-321
    • Shestopalov, I.1    Tice, J.D.2    Ismagilov, R.F.3
  • 20
    • 18044368667 scopus 로고    scopus 로고
    • A microfluidic approach for screening submicroliter volumes against multiple reagents by using preformed arrays of nanoliter plugs in a three-phase liquid/liquid/gas flow
    • This paper demonstrated the use of preloaded cartridges to perform enzymatic assays and protein crystallization on nanoliter scale.
    • Zheng B., and Ismagilov R.F. A microfluidic approach for screening submicroliter volumes against multiple reagents by using preformed arrays of nanoliter plugs in a three-phase liquid/liquid/gas flow. Angew Chem Int Ed 44 (2005) 2520-2523. This paper demonstrated the use of preloaded cartridges to perform enzymatic assays and protein crystallization on nanoliter scale.
    • (2005) Angew Chem Int Ed , vol.44 , pp. 2520-2523
    • Zheng, B.1    Ismagilov, R.F.2
  • 21
    • 4444257582 scopus 로고    scopus 로고
    • Formation of droplets of in microfluidic channels alternating composition and applications to indexing of concentrations in droplet-based assays
    • Zheng B., Tice J.D., and Ismagilov R.F. Formation of droplets of in microfluidic channels alternating composition and applications to indexing of concentrations in droplet-based assays. Anal Chem 76 (2004) 4977-4982
    • (2004) Anal Chem , vol.76 , pp. 4977-4982
    • Zheng, B.1    Tice, J.D.2    Ismagilov, R.F.3
  • 22
    • 13544250706 scopus 로고    scopus 로고
    • High-throughput microcoil NMR of compound libraries using zero-dispersion segmented flow analysis
    • Kautz R.A., Goetzinger W.K., and Karger B.L. High-throughput microcoil NMR of compound libraries using zero-dispersion segmented flow analysis. J Comb Chem 7 (2005) 14-20
    • (2005) J Comb Chem , vol.7 , pp. 14-20
    • Kautz, R.A.1    Goetzinger, W.K.2    Karger, B.L.3
  • 23
    • 25844517613 scopus 로고    scopus 로고
    • Using nanoliter plugs in microfluidics to facilitate and understand protein crystallization
    • Zheng B., Gerdts C.J., and Ismagilov R.F. Using nanoliter plugs in microfluidics to facilitate and understand protein crystallization. Curr Opin Struct Biol 15 (2005) 548-555
    • (2005) Curr Opin Struct Biol , vol.15 , pp. 548-555
    • Zheng, B.1    Gerdts, C.J.2    Ismagilov, R.F.3
  • 25
    • 13244289982 scopus 로고    scopus 로고
    • Controlling nonspecific protein adsorption in a plug-based microfluidic system by controlling interfacial chemistry using fluorous-phase surfactants
    • Roach L.S., Song H., and Ismagilov R.F. Controlling nonspecific protein adsorption in a plug-based microfluidic system by controlling interfacial chemistry using fluorous-phase surfactants. Anal Chem 77 (2005) 785-796
    • (2005) Anal Chem , vol.77 , pp. 785-796
    • Roach, L.S.1    Song, H.2    Ismagilov, R.F.3
  • 26
    • 0033824707 scopus 로고    scopus 로고
    • High-throughput quantitative bioanalysis by LC/MS/MS
    • Jemal M. High-throughput quantitative bioanalysis by LC/MS/MS. Biomed Chromatogr 14 (2000) 422-429
    • (2000) Biomed Chromatogr , vol.14 , pp. 422-429
    • Jemal, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.