Lung Lesions in SCID-bo and SCID-bg Mice after Intratracheal Inoculation with Wild-type or Leucotoxin-deficient Mutant Strains of Mannheimia haemolytica Serotype 1

Journal of Comparative Pathology

Volumn 134, Issue 4, 2006, Pages 355-365

  Gatto, N T ^a   Confer, A W ^c   Estes, D M ^b   Whitworth, L C ^c   Murphy, G L ^c  

^a OKLAHOMA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^c NONE

Author keywords

bacterial infection; cattle; leucotoxin; Mannheimia haemolytica; mouse; SCID bg mouse; SCID bo mouse

Indexed keywords

FORMALDEHYDE; LEUKOTOXIN; PHOSPHATE BUFFERED SALINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL PNEUMONIA; BACTERIAL STRAIN; BACTERIUM ISOLATION; BACTERIUM MUTANT; BRONCHIOLE; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; INOCULATION; LUNG ALVEOLUS MACROPHAGE; LUNG INFILTRATE; MANNHEIMIA HAEMOLYTICA; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PATHOGENESIS; SCID MOUSE; STATISTICAL SIGNIFICANCE; STRAIN DIFFERENCE; WILD TYPE;

ANIMALS; BACTERIAL TOXINS; BRONCHOPNEUMONIA; CATTLE; DISEASE MODELS, ANIMAL; EXOTOXINS; FEMALE; LUNG; MANNHEIMIA HAEMOLYTICA; MICE; MICE, SCID; PASTEURELLA INFECTIONS;

BACTERIA (MICROORGANISMS); BOS TAURUS; MANNHEIMIA HAEMOLYTICA SEROTYPE 1; RODENTIA;

EID: 33744459025     PISSN: 00219975     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcpa.2006.02.004     Document Type: Article

References (56)

1. Armitage, P. (1971). Statistical Methods in Medical Research, Blackwell Scientific, Oxford.
2. Asti C., Ruggieri V., Porzio S., Chiusaroli R., Melillo G., and Caselli G.F. Lipopolysaccharide-induced lung injury in mice. I. Concomitant evaluation of inflammatory cells and haemorrhagic lung damage. Pulmonary Pharmacology and Therapeutics 13 (2000) 61-69
3. Babiuk, L.A. and Acres, S.D. (1984). Models for bovine respiratory disease. In: Bovine Respiratory Disease: A Symposium, R.W. Loan, Ed., Texas A&M University Press, College Station, pp. 287-325.
4. Baggiolini M., Horisberger U., Gennaro R., and Dewald B. Identification of three types of granules in neutrophils of ruminants. Ultrastructure of circulating and maturing cells. Laboratory Investigation 52 (1985) 151-158
5. Baker J.C., and Frey M.L. Bovine respiratory syncytial virus. Veterinary Clinics of North America, Food Animal Practice 1 (1985) 259-275
6. Barbosa M.D., Nguyen Q.A., Tchernev V.T., Ashley J.A., Detter J.C., Blaydes S.M., Brandt S.J., Chotai D., Hodgman C., Solari R.C., Lovett M., and Kingsmore S.F. Identification of the homologous beige and Chediak-Higashi syndrome genes. Nature 382 (1996) 262-265
7. Bauer M.E., and Welch R.A. Characterization of an RTX toxin from enterohemorrhagic Escherichia coli O157:H7. Infection and Immunity 64 (1996) 167-175
8. Beck M., van den Bosch J.F., Jongenelen I.M., Loeffen P.L., Nielsen R., Nicolet J., and Frey J. RTX toxin genotypes and phenotypes in Actinobacillus pleuropneumoniae field strains. Journal of Clinical Microbiology 32 (1994) 2749-2754
9. Bosma M.J., and Carroll A.M. The SCID mouse mutant: definition, characterization, and potential uses. Annual Review of Immunology 9 (1991) 323-350
10. Breider M.A., Walker R.D., Hopkins F.M., Schultz T.W., and Bowersock T.L. Pulmonary lesions induced by Pasteurella haemolytica in neutrophil sufficient and neutrophil deficient calves. Canadian Journal of Veterinary Research 52 (1988) 205-209
11. Burrows L.L., and Lo R.Y. Molecular characterization of an RTX toxin determinant from Actinobacillus suis. Infection and Immunity 60 (1992) 2166-2173
12. Clarke C.R., Confer A.W., and Mosier D.A. In vivo effect of Pasteurella haemolytica infection on bovine neutrophil morphology. American Journal of Veterinary Research 59 (1998) 588-592
13. Clarke C.R., Lauer A.K., Barron S.J., and Wyckoff J.H. The role of eicosanoids in the chemotactic response to Pasteurella haemolytica infection. Zentralblatt für Veterinärmedizin Series B 41 (1994) 483-491
14. Clinkenbeard K.D., Clarke C.R., Morton R.J., Mosier D.A., Panciera R.J., and Confer A.W. Role of Pasteurella haemolytica leukotoxin in virulence and immunity in shipping fever pneumonia. Compendium for Continuing Education for the Practicing Veterinarian 14 (1992) 1249-1260
15. Clinkenbeard K.D., and Upton M.L. Lysis of bovine platelets by Pasteurella haemolytica leukotoxin. American Journal of Veterinary Research 52 (1991) 453-457
16. Confer A.W., and Simons K.R. Effects of Pasteurella haemolytica lipopolysaccharide on selected functions of bovine leukocytes. American Journal of Veterinary Research 47 (1986) 154-157
17. Confer A.W., Simons K.R., Barrie M.T., and Clinkenbeard K.D. Effects of Pasteurella haemolytica leukotoxin on neutrophils from white-tailed deer and several exotic ruminant species. Veterinary Research Communications 14 (1990) 175-180
18. Cudd L., Clarke C., Clinkenbeard K., Shelton M., Clinkenbeard P., and Murphy G. Role of intracellular calcium in Pasteurella haemolytica leukotoxin-induced bovine neutrophil leukotriene B4 production and plasma membrane damage. FEMS Microbiology Letters 172 (1999) 123-129
19. Davies R.L., and Baillie S. Cytotoxic activity of Mannheimia haemolytica strains in relation to diversity of the leukotoxin structural gene lktA. Veterinary Microbiology 92 (2003) 263-279
20. Denny S.L., Brackett N.Y., Mann F.A., Kreeger J.M., and Estes D.M. Antigen-specific humoral immune responses to a hapten-carrier conjugate in SCID mice engrafted with bovine fetal haematopoietic tissues. Laboratory Animal Science 46 (1996) 48-55
21. Dungworth, D.L. (1993). The respiratory system. In: Pathology of Domestic Animals, K.V.R. Jubb, P.C. Kennedy and N. Palmer, Eds, Academic Press, New York, pp. 633-638.
22. Evans H.B., and Wells P.W. A mouse model of Pasteurella haemolytica infection and its use in assessment of the efficacy of P. haemolytica vaccines. Research in Veterinary Science 27 (1979) 213-217
23. Filion L.G., Willson P.J., Bielefeldt-Ohmann H., Babiuk L.A., and Thomson R.G. The possible role of stress in the induction of pneumonic pasteurellosis. Canadian Journal of Comparative Medicine 48 (1984) 268-274
24. Florido M., Appelberg R., Orme I.M., and Cooper A.M. Evidence for a reduced chemokine response in the lungs of beige mice infected with Mycobacterium avium. Immunology 90 (1997) 600-606
25. Gentry M.J., Confer A.W., and Panciera R.J. Serum neutralization of cytotoxin from Pasteurella haemolytica, serotype 1 and resistance to experimental bovine pneumonic pasteurellosis. Veterinary Immunology and Immunopathology 9 (1985) 239-250
26. Griffin D. Economic impact associated with respiratory disease in beef cattle. Veterinary Clinics of North America, Food Animal Practice 13 (1997) 367-377
27. Haas K.M., Taylor K.A., MacHugh N.D., Kreeger J.M., and Estes D.M. Enhancing effects of anti-CD40 treatment on the immune response of SCID-bovine mice to Trypanosoma congolense infection. Journal of Leukocyte Biology 70 (2001) 931-940
28. Henkel K.A., Swenson C.S., Richardson B., and Common R. Morphology, cytochemical staining, and ultrastructural characteristics of reindeer (Rangier tarandus) leukocytes. Veterinary Clinical Pathology 28 (1999) 8-15
29. Highlander S.K., Fedorova N.D., Dusek D.M., Panciera R., Alvarez L.E., and Rinehart C. Inactivation of Pasteurella (Mannheimia) haemolytica leukotoxin causes partial attenuation of virulence in a calf challenge model. Infection and Immunity 68 (2000) 3916-3922
30. Hochberg, M.C. (1989). NSAIDS: mechanisms and pathways of action. Hospital Practice, 24, 185-190, 195, 198.
31. Houghton S.B., and Gourlay R.N. Synergism between Mycoplasma bovis and Pasteurella haemolytica in calf pneumonia. Veterinary Record 113 (1983) 41-42
32. Kocan K.M., Hsu K.C., Hair J.A., and Ewing S.A. Demonstration of Anaplasma marginale Theiler in Dermacentor variabilis (Say) by ferritin-conjugated antibody technique. American Journal of Veterinary Research 41 (1980) 1977-1981
33. Kubo A., Sasada M., Nishimura T., Moriguchi T., Kakita T., Yamamoto K., and Uchino H. Oxygen radical generation by polymorphonuclear leucocytes of beige mice. Clinical and Experimental Immunology 70 (1987) 658-663
34. Lear J.D., Furblur U.G., Lally E.T., and Tanaka J.C. Actinobacillus actinomycetemcomitans leukotoxin forms large conductance, voltage-gated ion channels when incorporated into planar lipid bilayers. Biochimica et Biophysica Acta 1238 (1995) 34-41
35. Lo R.Y. Molecular characterization of cytotoxins produced by Haemophilus, Actinobacillus, Pasteurella. Canadian Journal of Veterinary Research 54 Suppl. (1990) S33-S35
36. Lopez A., Thomson R.G., and Savan M. The pulmonary clearance of Pasteurella hemolytica in calves infected with bovine parainfluenza-3 virus. Canadian Journal of Comparative Medicine 40 (1976) 385-391
37. Menestrina G., Moser C., Pellet S., and Welch R. Pore-formation by Escherichia coli hemolysin (Hly A) and other members of the RTX toxins family. Toxicology 87 (1994) 249-267
38. Miles A.A., and Misra S.S. The estimation of the bactericidal power of the blood. Journal of Hygiene 38 (1938) 732-749
39. Murphy G.L., Whitworth L.C., Clinkenbeard K.D., and Clinkenbeard P.A. Hemolytic activity of the Pasteurella haemolytica leukotoxin. Infection and Immunity 63 (1995) 3209-3212
40. Perdrizet J.A., Rebhun W.C., Dubovi E.J., and Donis R.O. Bovine virus diarrhea clinical syndromes in dairy herds. Cornell Veterinarian 77 (1987) 46-74
41. Petras S.F., Chidambaram M., Illyes E.F., Froshauer S., Weinstock G.M., and Reese C.P. Antigenic and virulence properties of Pasteurella haemolytica leukotoxin mutants. Infection and Immunity 63 (1995) 1033-1039
42. Roder J., and Duwe A. The beige mutation in the mouse selectively impairs natural killer cell function. Nature 278 (1979) 451-453
43. Rose T., Sebo P., Bellalou J., and Ladant D. Interaction of calcium with Bordetella pertussis adenylate cyclase toxin. Characterization of multiple calcium-binding sites and calcium-induced conformational changes. Journal of Biological Chemistry 270 (1995) 26370-26376
44. Roth, J.A. (1984). Immunosuppression and immunomodulation in bovine respiratory disease. In: Bovine Respiratory Disease: A Symposium, R.W. Loan, Ed., Texas A&M University Press, College Station, pp. 143-192.
45. Smith R.A., Kreeger J.M., Alvarez A.J., Goin J.C., Davis W.C., Whipple D.L., and Estes D.M. Role of CD8+ and WC-1+ gamma/delta T cells in resistance to Mycobacterium bovis infection in the SCID-bo mouse. Journal of Leukocyte Biology 65 (1999) 28-34
46. Srinand S., Maheswaran S.K., Ames T.R., Werdin R.E., and Hsuan S.L. Evaluation of efficacy of three commercial vaccines against experimental bovine pneumonic pasteurellosis. Veterinary Microbiology 52 (1996) 81-89
47. Sun Y., Clinkenbeard K.D., Cudd L.A., Clarke C.R., and Clinkenbeard P.A. Correlation of Pasteurella haemolytica leukotoxin binding with susceptibility to intoxication of lymphoid cells from various species. Infection and Immunity 67 (1999) 6264-6269
48. Takeuchi K., Wood H., and Swank R.T. Lysosomal elastase and cathepsin G in beige mice. Neutrophils of beige (Chediak-Higashi) mice selectively lack lysosomal elastase and cathepsin G. Journal of Experimental Medicine 163 (1986) 665-677
49. Thorn C.E., Papp J.R., Shewen P.E., and Stirtzinger T. Experimentally induced pneumonia in scid/beige mice, using bovine isolate of Pasteurella haemolytica. Comparative Medicine 50 (2000) 153-159
50. Vassalli J.D., Granelli-Piperno A., Griscelli C., and Reich E. Specific protease deficiency in polymorphonuclear leukocytes of Chediak-Higashi syndrome and beige mice. Journal of Experimental Medicine 147 (1978) 1285-1290
51. Watson G.L., Slocombe R.F., Robinson N.E., and Sleight S.D. Enzyme release by bovine neutrophils. American Journal of Veterinary Research 56 (1995) 1055-1061
52. Welch R.A. Pore-forming cytolysins of gram-negative bacteria. Molecular Microbiology 5 (1991) 521-528
53. Welsh R.D. Bacterial and Mycoplasma species isolated from pneumonic bovine lungs. Agri-Practice 14 (1993) 12-16
54. Welsh R.D., Dye L.B., Payton M.E., and Confer A.W. Frequency of isolation and antimicrobial susceptibilities of bacterial pathogens from bovine pneumonia: 1994-2002. Journal of Veterinary Diagnostic Investigation 16 (2004) 426-431
55. Whiteley L.O., Maheswaran S.K., Weiss D.J., and Ames T.R. Morphological and morphometrical analysis of the acute response of the bovine alveolar wall to Pasteurella haemolytica A1-derived endotoxin and leukotoxin. Journal of Comparative Pathology 104 (1991) 23-32
56. Wilkie B.N., and Markham R.J. Sequential titration of bovine lung and serum antibodies after parenteral or pulmonary inoculation with Pasteurella haemolytica. American Journal of Veterinary Research 40 (1979) 1690-1693