Asymmetric synthesis of (-)-nupharamine and (-)-(5S,8R,9S)-5-(3-furyl)-8- methyloctahydroindolizidine from β-amino ketones and the intramolecular Mannich reaction

Journal of Organic Chemistry

Volumn 71, Issue 11, 2006, Pages 4222-4226

  Davis, Franklin A ^a   Santhanaraman, Manikandan ^a  

^a Temple University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO KETONES; ANTITUMOR NUPHAR ALKALOIDS; ASYMMETRIC SYNTHESIS; TRISUBSTITUTED PIPERIDINE;

AMINO ACIDS; CONFORMATIONS; KETONES; MOLECULAR ORIENTATION; REACTION KINETICS; SYNTHESIS (CHEMICAL);

AMINES;

5 (3 FURYL) 8 METHYLOCTAHYDROINDOLIZIDINE; ALKALOID DERIVATIVE; AMINOKETONE; ANTINEOPLASTIC AGENT; BETA AMINOKETONE; INDOLIZIDINE DERIVATIVE; NUPHARAMINE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; MANNICH REACTION; NUPHAR; REACTION ANALYSIS; STRUCTURE ANALYSIS;

ALKALOIDS; FURANS; INDOLIZINES; KETONES; MOLECULAR STRUCTURE; PIPERIDINES;

EID: 33646917172     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo060371j     Document Type: Article

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