Staphylococcus aureus enterotoxin D is secreted in milk and stimulates specific antibody responses in cows in the course of experimental intramammary infection

Infection and Immunity

Volumn 74, Issue 6, 2006, Pages 3507-3512

  Tollersrud, Tore ^a   Kampen, Annette H ^a   Kenny, Kevin ^b,c  

^a NORWEGIAN VETERINARY INSTITUTE   (Norway)

^b Cornell University ^*  (United States)

^c National Veterinary Institute ^*  (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; ENTEROTOXIN; IMMUNOGLOBULIN G2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY BLOOD LEVEL; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ANTIBODY SPECIFICITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DAIRY CATTLE; DISEASE COURSE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; IN VITRO STUDY; LACTATION; LYMPHOCYTE PROLIFERATION; MAMMARY GLAND; MASTITIS; MILK; MITOGENESIS; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; STAPHYLOCOCCUS AUREUS;

ANIMALS; ANTIBODIES, BACTERIAL; CATTLE; ENTEROTOXINS; FEMALE; LYMPHOCYTE ACTIVATION; MAMMARY GLANDS, ANIMAL; MASTITIS, BOVINE; MILK; NEUTROPHILS; STAPHYLOCOCCAL INFECTIONS; SUPERANTIGENS;

EID: 33646907373     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.01726-05     Document Type: Article

References (45)

1. Anderson, J. C. 1982. Progressive pathology of staphylococcal mastitis with a note on control, immunisation and therapy. Vet. Rec. 110:372-376.
2. Barrio, M. B., P. Rainard, and B. Poutrel. 2003. Milk complement and the opsonophagocytosis and killing of Staphylococcus aureus mastitis isolates by bovine neutrophils. Microb. Pathog. 34:1-9.
3. Bohach, G. A., M. M. Dinges, D. T. Mitchell, D. H. Ohlendorf, and P. M. Schlievert. 1997. Exotoxins, p. 83-112. In K. B. Crossley and G. L. Archer (ed.), The staphylococci in human disease. Churchill Livingstone, New York, N.Y.
4. Carlson, G. P., and J. J. Kaneko. 1973. Isolation of leukocytes from bovine peripheral blood. Proc. Soc. Exp. Biol. Med. 142:853-856.
5. Deringer, J. R., R. J. Ely, S. R. Monday, C. V. Stauffacher, and G. A. Bohach. 1997. Vβ-dependent stimulation of bovine and human T cells by host-specific staphylococcal enterotoxins. Infect. Immun. 65:4048-4054.
6. Dinges, M. M., P. M. Orwin, and P. M. Schlievert. 2000. Exotoxins of Staphylococcus aureus. Clin. Microbiol. Rev. 13:16-34.
7. Donnelly, R. P., and T. J. Rogers. 1982. Immunosuppression induced by staphylococcal enterotoxin B. Cell. Immunol. 72:166-177.
8. Ferens, W. A., W. C. Davis, M. J. Hamilton, Y. H. Park, C. F. Deobald, L. Fox, and G. Bohach. 1998. Activation of bovine lymphocyte subpopulations by staphylococcal enterotoxin C. Infect. Immun. 66:573-580.
9. Ferens, W. A., W. L. Goff, W. C. Davis, L. K. Fox, C. Deobald, M. J. Hamilton, and G. A. Bohach. 1998. Induction of type 2 cytokines by a staphylococcal enterotoxin superantigen. J. Nat. Toxins. 7:193-213.
10. Fitzgerald, J. R., S. R. Monday, T. J. Foster, G. A. Bohach, P. J. Hartigan, W. J. Meaney, and C. J. Smyth. 2001. Characterization of a putative pathogenicity island from bovine Staphylococcus aureus encoding multiple superantigens. J. Bacteriol. 183:63-70.
11. Fitzpatrick, J. L., P. J. Cripps, A. W. Hill, P. W. Bland, and C. R. Stokes. 1992. MHC class II expression in the bovine mammary gland. Vet. Immunol. Immunopathol. 32:13-23.
12. Jones, T. O., and A. A. Wieneke. 1986. Staphylococcal toxic shock syndrome. Vet. Rec. 119:435-436.
13. Jørgensen, H. J., T. Mørk, H. R. Høgåsen, and L. M. Rørvik. 2005. Enterotoxigenic Staphylococcus aureus in bulk milk in Norway. J. Appl. Microbiol. 99:158-166.
14. Kampen, A. H., T. Tollersrud, S. Larsen, J. A. Roth, D. E. Frank, and A. Lund. 2004. Repeatability of flow cytometric and classical measurement of phagocytosis and respiratory burst in bovine polymorphonuclear leukocytes. Vet. Immunol. Immunopathol. 97:105-114.
15. Kampen, A. H., T. Tollersrud, and A. Lund. 2004. Flow cytometric measurement of neutrophil respiratory burst in whole bovine blood using live Staphylococcus aureus. J. Immunol. Methods 289:47-55.
16. Kampen, A. H., T. Tollersrud, and A. Lund. 2005. Staphylococcus aureus capsular polysaccharide types 5 and 8 reduce killing by bovine neutrophils in vitro. Infect. Immun. 73:1578-1583.
17. Kappler, J., B. Kotzin, L. Herron, E. W. Gelfand, R. D. Bigler, A. Boylston, S. Carrel, D. N. Posnett, Y. Choi, and P. Marrack. 1989. Vβ-specific stimulation of human T cells by staphylococcal toxins. Science 244:811-813.
18. Kenny, K. 1992. The contribution of alpha-hemolysin to bovine Staphylococcus aureus mastitis. Thesis. Cornell University, Ithaca, N.Y.
19. Kenny, K., R. F. Reiser, F. D. Bastida-Corcuera, and N. L. Norcross. 1993. Production of enterotoxins and toxic shock syndrome toxin by bovine mammary isolates of Staphylococcus aureus. J. Clin. Microbiol. 31:706-707.
20. Kuroishi, T., K. Komine, K. Asai, J. Kobayashi, K. Watanabe, T. Yamaguchi, S. Kamata, and K. Kumagai. 2003. Inflammatory responses of bovine polymorphonuclear neutrophils induced by staphylococcal enterotoxin C via stimulation of mononuclear cells. Clin. Diagn. Lab. Immunol. 10:1011-1018.
21. Kuroishi, T., K. Komine, K. Kai, M. Itagaki, J. Kobayashi, M. Ohta, S. Kamata, and K. Kumagai. 2003. Concentrations and specific antibodies to staphylococcal enterotoxin-C and toxic shock syndrome toxin-1 in bovine mammary gland secretions, and inflammatory response to the intramammary inoculation of these toxins. J. Vet. Med. Sci. 65:899-906.
22. Larsen, H. D., F. M. Aarestrup, and N. E. Jensen. 2002. Geographical variation in the presence of genes encoding superantigenic exotoxins and β-hemolysin among Staphylococcus aureus isolated from bovine mastitis in Europe and USA. Vet. Microbiol. 85:61-67.
23. Larsen, H. D., A. Huda, N. H. Eriksen, and N. E. Jensen. 2000. Differences between Danish bovine and human Staphylococcus aureus isolates in possession of superantigens. Vet. Microbiol. 76:153-162.
24. Larsen, H. J. 1979. A whole blood method for measuring mitogen-induced transformation of sheep lymphocytes. Res. Vet. Sci. 27:334-338.
25. Lascelles, A. K. 1979. The immune system of the ruminant mammary gland and its role in the control of mastitis. J. Dairy Sci. 62:154-160.
26. Lowell, G. H., C. Colleton, D. Frost, R. W. Kaminski, M. Hughes, J. Hatch, C. Hooper, J. Estep, L. Pitt, M. Topper, R. E. Hunt, W. Baker, and W. B. Baze. 1996. Immunogenicity and efficacy against lethal aerosol staphylococcal enterotoxin B challenge in monkeys by intramuscular and respiratory delivery of proteosome-toxoid vaccines. Infect. Immun. 64:4686-1693.
27. Matsunaga, T., S. Kamata, N. Kakiichi, and K. Uchida. 1993. Characteristics of Staphylococcus aureus isolated from peracute, acute and chronic bovine mastitis. J. Vet. Med. Sci. 55:297-300.
28. Moulding, D. A., C. Walter, C. A. Hart, and S. W. Edwards. 1999. Effects of staphylococcal enterotoxins on human neutrophil functions and apoptosis. Infect. Immun. 67:2312-2318.
29. Mullarky, I. K., C. Su, N. Frieze, Y. H. Park, and L. M. Sordillo. 2001. Staphylococcus aureus agr genotypes with enterotoxin production capabilities can resist neutrophil bactericidal activity. Infect. Immun. 69:45-51.
30. Nilsson, I. M., M. Verdrengh, R. G. Ulrich, S. Bavari, and A. Tarkowski. 1999. Protection against Staphylococcus aureus sepsis by vaccination with recombinant staphylococcal enterotoxin A devoid of superantigenicity. J. Infect. Dis. 180:1370-1373.
31. Niskanen, A., L. Koranen, and K. Roine. 1978. Staphylococcal enterotoxin and thermonuclease production during induced bovine mastitis and the clinical reaction of enterotoxin in udders. Infect. Immun. 19:493-498.
32. Papageorgiou, A. C., and K. R. Acharya. 2000. Microbial superantigens: from structure to function. Trends Microbiol. 8:369-375.
33. Park, Y. H., L. K. Fox, M. J. Hamilton, and W. C. Davis. 1993. Suppression of proliferative response of BoCD4+ T lymphocytes by activated BoCD8+ T lymphocytes in the mammary gland of cows with Staphylococcus aureus mastitis. Vet. Immunol. Immunopathol. 36:137-151.
34. Pinto, M., M. Torten, and S. C. Birnbaum. 1978. Suppression of the in vivo humoral and cellular immune response by staphylococcal enterotoxin B (SEB). Transplantation 25:320-323.
35. Schlievert, P. M., L. M. Jablonski, M. Roggiani, I. Sadler, S. Callantine, D. T. Mitchell, D. H. Ohlendorf, and G. A. Bohach. 2000. Pyrogenic toxin superantigen site specificity in toxic shock syndrome and food poisoning in animals. Infect. Immun. 68:3630-3634.
36. Smyth, D. S., P. J. Hartigan, W. J. Meaney, J. R. Fitzgerald, C. F. Deobald, G. A. Bohach, and C. J. Smyth. 2005. Superantigen genes encoded by the egc cluster and SaPlbov are predominant among Staphylococcus aureus isolates from cows, goats, sheep, rabbits and poultry. J. Med. Microbiol. 54:401-411.
37. Stevens, M. G., M. E. Kehrli, Jr., and P. C. Canning. 1991. A colorimetric assay for quantitating bovine neutrophil bactericidal activity. Vet. Immunol. Immunopathol. 28:45-56.
38. Stiles, B. G., A. R. Garza, R. G. Ulrich, and J. W. Boles. 2001. Mucosal vaccination with recombinantly attenuated staphylococcal enterotoxin B and protection in a murine model. Infect. Immun. 69:2031-2036.
39. Sutra, L., and B. Poutrel. 1994. Virulence factors involved in the pathogenesis of bovine intramammary infections due to Staphylococcus aureus. J. Med. Microbiol. 40:79-89.
40. Tollersrud, T., K. Kenny, D. A. Caugant, and A. Lund. 2000. Characterisation of isolates of Staphylococcus aureus from acute, chronic and subclinical mastitis in cows in Norway. APMIS 108:565-572.
41. Ulrich, R. G. 2000. Evolving superantigens of Staphylococcus aureus. FEMS Immunol. Med. Microbiol. 27:1-7.
42. Waage, S., H. R. Skei, J. Rise, T. Rogdo, S. Sviland, and S. A. Ødegaard. 2000. Outcome of clinical mastitis in dairy heifers assessed by reexamination of cases one month after treatment. J. Dairy Sci. 83:70-76.
43. Watson, D. L. 1976. The effect of cytophilic IgG2 on phagocytosis by ovine polymorphonuclear leucocytes. Immunology 31:159-165.
44. White, J., A. Herman, A. M. Pullen, R. Kubo, J. W. Kappler, and P. Marrack. 1989. The V β-specific superantigen staphylococcal enterotoxin B: stimulation of mature T cells and clonal deletion in neonatal mice. Cell 56:27-35.
45. Yokomizo, Y., Y. Mori, Y. Shimoji, S. Shimizu, H. Sentsui, M. Kodama, and H. Igarashi. 1995. Proliferative response and cytokine production of bovine peripheral blood mononuclear cells induced by the superantigens staphylococcal enterotoxins and toxic shock syndrome toxin-1. J. Vet. Med. Sci. 57:299-305.