Mapping and characterization of protein epitopes using the SPOT method

Cell Biology: A Laboratory Handbook

Volumn , Issue , 2005, Pages 519-525

  Granier, Claude ^a   Villard, Sylvie ^b   Laune, Daniel ^b  

^a UNIV MONTPELLIER   (France)

^b CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33646905211     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012164730-8/50063-0     Document Type: Chapter

References (10)

1. Frank R. Spot-Synthesis: An easy technique for the positionally addressable, parallel chemical synthesis on a membrane support. Tetrahedrom 1992, 48:9217-9232.
2. Geysen H.M., Meloen R.H., Barteling S.J. Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acid. Proc. Natl. Acad. Sci. USA 1984, 81:3998-4002.
3. Geysen H.M., Rodda S.J., Mason T.J. A priori delineation of a peptide which mimics a discontinuous antigenic determinant. Mol. Immunol. 1986, 23:709-715.
4. Granier C. Special issue on "Methods of parallel peptide synthesis and their contributions to deciphering molecular interactions in the immune system". J. Immunol. Methods 2002, 267:1-2.
5. Koch J., Mahler M. Peptide Arrays on Membrane Supports: Synthesis and Applications 2002, Springer-Verlag, Berlin.
6. Molina F., Laune D., Gougat C., Pau B., Granier C. Improved performances of Spot multiple peptide synthesis. Pept. Res. 1996, 9:151-155.
7. Reineke U., Kramer A., Schneider-Mergener J. Antigen sequence- and library-based mapping of linear and discontinuous protein-protein-interaction sites by Spot synthesis. Curr. Top. Microbiol. Immunol. 1999, 243:23-36.
8. Reineke U., Sabat R., Misselwitz R., Welfle H., Volk H.D., Schneider-Mergener J. A synthetic mimic of a discontinuous binding site on interleukin-10. Nature Biotechnol. 1999, 17:271-275.
9. Van Regenmortel M.H., Pellequer J.L. Predicting antigenic determinants in proteins: Looking for unidimensional solutions to a three-dimensional problem?. Pept. Res. 1994, 7:224-228.
10. Villard S., Piquer D., Raut S., Leonetti J.P., Saint-Remy J.M., Granier C. Low molecular weight peptides restore the procoagulant activity of factor VIII in the presence of the potent inhibitor antibody ESH8. J. Biol. Chem. 2002, 277:27232-27239.