메뉴 건너뛰기




Volumn 8, Issue 2, 2006, Pages 131-137

Microvascular damage in systemic sclerosis: Detection and monitoring with biomarkers

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; ENDOTHELIN 1; VASCULOTROPIN;

EID: 33646903472     PISSN: 15233774     EISSN: 15346307     Source Type: Journal    
DOI: 10.1007/s11926-006-0053-z     Document Type: Review
Times cited : (12)

References (55)
  • 1
    • 0020520743 scopus 로고
    • Prevalence and clinical correlates of pulmonary arterial hypertension in progressive systemic sclerosis
    • Ungerer RG, Tashkin DP, Furst D, et al.: Prevalence and clinical correlates of pulmonary arterial hypertension in progressive systemic sclerosis. Am J Med 1983, 75:65-74.
    • (1983) Am J Med , vol.75 , pp. 65-74
    • Ungerer, R.G.1    Tashkin, D.P.2    Furst, D.3
  • 2
    • 0028025527 scopus 로고
    • Serial nailfold capillary microscopy in primary Raynaud's phenomenon and scleroderma
    • ter Borg EJ, Piersma-Wichers G, Smit AJ, et al.: Serial nailfold capillary microscopy in primary Raynaud's phenomenon and scleroderma. Semin Arthritis Rheum 1994, 24:40-47.
    • (1994) Semin Arthritis Rheum , vol.24 , pp. 40-47
    • Ter Borg, E.J.1    Piersma-Wichers, G.2    Smit, A.J.3
  • 3
    • 0030980128 scopus 로고    scopus 로고
    • Nailfold capillary abnormality and pulmonary hypertension in systemic sclerosis
    • Ohtsuka T, Hasegawa A, Nakano A, et al.: Nailfold capillary abnormality and pulmonary hypertension in systemic sclerosis. Int J Dermatol 1997, 36:116-122.
    • (1997) Int J Dermatol , vol.36 , pp. 116-122
    • Ohtsuka, T.1    Hasegawa, A.2    Nakano, A.3
  • 4
    • 0032411469 scopus 로고    scopus 로고
    • Decreased nailfold capillary density in limited scleroderma with pulmonary hypertension
    • Ong YY, Nikoloutsopoulos T, Bond CP, et al.: Decreased nailfold capillary density in limited scleroderma with pulmonary hypertension. Asian Pac J Allergy Immunol 1998, 16:81-86.
    • (1998) Asian Pac J Allergy Immunol , vol.16 , pp. 81-86
    • Ong, Y.Y.1    Nikoloutsopoulos, T.2    Bond, C.P.3
  • 5
    • 0037331671 scopus 로고    scopus 로고
    • Predictors of isolated pulmonary hypertension in patients with systemic sclerosis and limited cutaneous involvement
    • Steen V, Medsger TA, Jr.: Predictors of isolated pulmonary hypertension in patients with systemic sclerosis and limited cutaneous involvement. Arthritis Rheum 2003, 48:516-522. This case-control study looked retrospectively at clinical predictors of PAH among patients with limited scleroderma. They found that there was a linear decline in diffusing capacity years preceding the diagnosis of PAH.
    • (2003) Arthritis Rheum , vol.48 , pp. 516-522
    • Steen, V.1    Medsger Jr., T.A.2
  • 6
    • 0033736351 scopus 로고    scopus 로고
    • Assessment of damage and activity in systemic sclerosis
    • Medsger TA, Jr.: Assessment of damage and activity in systemic sclerosis. Curr Opin Rheumatol 2000, 12:545-548.
    • (2000) Curr Opin Rheumatol , vol.12 , pp. 545-548
    • Medsger Jr., T.A.1
  • 7
    • 0344980376 scopus 로고    scopus 로고
    • A disease severity scale for systemic sclerosis: Development and testing
    • Medsger TA Jr., Silman AJ, Steen VD, et al.: A disease severity scale for systemic sclerosis: development and testing. J Rheumatol 1999, 26:2159-2167.
    • (1999) J Rheumatol , vol.26 , pp. 2159-2167
    • Medsger Jr., T.A.1    Silman, A.J.2    Steen, V.D.3
  • 8
    • 0035080134 scopus 로고    scopus 로고
    • The Disability Index of the Health Assessment Questionnaire is a predictor and correlate of outcome in the high-dose versus low-dose penicillamine in systemic sclerosis trial
    • Clements PJ, Wong WK, Hurwitz EL, et al.: The Disability Index of the Health Assessment Questionnaire is a predictor and correlate of outcome in the high-dose versus low-dose penicillamine in systemic sclerosis trial. Arthritis Rheum 2001, 44:653-661.
    • (2001) Arthritis Rheum , vol.44 , pp. 653-661
    • Clements, P.J.1    Wong, W.K.2    Hurwitz, E.L.3
  • 9
    • 0035100888 scopus 로고    scopus 로고
    • Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework
    • Biomarkers Definitions Working Group
    • Biomarkers Definitions Working Group: Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clin Pharmacol Ther 2001, 69:89-95.
    • (2001) Clin Pharmacol Ther , vol.69 , pp. 89-95
  • 10
    • 4444243652 scopus 로고    scopus 로고
    • Vascular involvement in systemic sclerosis (SSc)
    • Kahaleh MB: Vascular involvement in systemic sclerosis (SSc). Clin Exp Rheumatol 2004, 22(Suppl 33):S19-S23. This is a nice overview of the history and recent progress in our understanding of the scleroderma vascular disease.
    • Clin Exp Rheumatol 2004 , vol.22 , Issue.SUPPL. 33
    • Kahaleh, M.B.1
  • 11
    • 0029999963 scopus 로고    scopus 로고
    • Endothelial cell apoptosis is a primary pathogenetic event underlying skin lesions in avian and human scleroderma
    • Sgonc R, Gruschwitz MS, Dietrich H, et al.: Endothelial cell apoptosis is a primary pathogenetic event underlying skin lesions in avian and human scleroderma. J Clin Invest 1996, 98:785-792.
    • (1996) J Clin Invest , vol.98 , pp. 785-792
    • Sgonc, R.1    Gruschwitz, M.S.2    Dietrich, H.3
  • 12
    • 0031127473 scopus 로고    scopus 로고
    • Mechanism of serum-mediated endothelial injury in scleroderma: Identification of a granular enzyme in scleroderma skin and sera
    • Kahaleh MB, Fan PS: Mechanism of serum-mediated endothelial injury in scleroderma: identification of a granular enzyme in scleroderma skin and sera. Clin Immunol Immunopathol 1997, 83:32-40.
    • (1997) Clin Immunol Immunopathol , vol.83 , pp. 32-40
    • Kahaleh, M.B.1    Fan, P.S.2
  • 13
    • 0033758304 scopus 로고    scopus 로고
    • Endothelial cell apoptosis in systemic sclerosis is induced by antibody-dependent cell-mediated cytotoxicity via CD95
    • Sgonc R, Gruschwitz MS, Boeck G, et al.: Endothelial cell apoptosis in systemic sclerosis is induced by antibody-dependent cell-mediated cytotoxicity via CD95. Arthritis Rheum 2000, 43:2550-2562.
    • (2000) Arthritis Rheum , vol.43 , pp. 2550-2562
    • Sgonc, R.1    Gruschwitz, M.S.2    Boeck, G.3
  • 14
    • 0033983441 scopus 로고    scopus 로고
    • Characterization of autoantibodies to endothelial cells in systemic sclerosis (SSc): Association with pulmonary fibrosis
    • Ihn H, Sato S, Fujimoto M, et al.: Characterization of autoantibodies to endothelial cells in systemic sclerosis (SSc): association with pulmonary fibrosis. Clin Exp Immunol 2000, 119:203-209.
    • (2000) Clin Exp Immunol , vol.119 , pp. 203-209
    • Ihn, H.1    Sato, S.2    Fujimoto, M.3
  • 15
    • 24744455197 scopus 로고    scopus 로고
    • Anti-endothelial cell antibodies in idiopathic and systemic sclerosis associated pulmonary arterial hypertension
    • Tamby MC, Chanseaud Y, Humbert M, et al.: Anti-endothelial cell antibodies in idiopathic and systemic sclerosis associated pulmonary arterial hypertension. Thorax 2005, 60:765-772.
    • (2005) Thorax , vol.60 , pp. 765-772
    • Tamby, M.C.1    Chanseaud, Y.2    Humbert, M.3
  • 16
    • 0033498335 scopus 로고    scopus 로고
    • Autoimmunity and vascular involvement in systemic sclerosis (SSc)
    • Kahaleh MB, LeRoy EC: Autoimmunity and vascular involvement in systemic sclerosis (SSc). Autoimmumty 1999, 31:195-214.
    • (1999) Autoimmumty , vol.31 , pp. 195-214
    • Kahaleh, M.B.1    LeRoy, E.C.2
  • 17
    • 0023358871 scopus 로고
    • Plasma von Willebrand factor in connective tissue disease
    • Gordon JL, Pottinger BE, Woo P, et al.: Plasma von Willebrand factor in connective tissue disease. Ann Rheum Dis 1987, 46:491-492.
    • (1987) Ann Rheum Dis , vol.46 , pp. 491-492
    • Gordon, J.L.1    Pottinger, B.E.2    Woo, P.3
  • 18
    • 0026950415 scopus 로고
    • Tissue-type plasminogen activator and von Willebrand factor plasma levels as markers of endothelial involvement in patients with Raynaud's phenomenon
    • Marasini B, Cugno M, Bassani C, et al.: Tissue-type plasminogen activator and von Willebrand factor plasma levels as markers of endothelial involvement in patients with Raynaud's phenomenon. Int J Microcirc Clin Exp 1992, 11:375-382.
    • (1992) Int J Microcirc Clin Exp , vol.11 , pp. 375-382
    • Marasini, B.1    Cugno, M.2    Bassani, C.3
  • 19
    • 0027426209 scopus 로고
    • Mechanisms of endothelial cell damage in systemic sclerosis and Raynaud's phenomenon
    • Blann AD, Illingworth K, Jayson MI: Mechanisms of endothelial cell damage in systemic sclerosis and Raynaud's phenomenon. J Rheumatol 1993, 20:1325-1330.
    • (1993) J Rheumatol , vol.20 , pp. 1325-1330
    • Blann, A.D.1    Illingworth, K.2    Jayson, M.I.3
  • 20
    • 0030071159 scopus 로고    scopus 로고
    • Von Willebrand factor, thrombomodulin, thromboxane, beta-thromboglobulin and markers of fibrinolysis in primary Raynaud's phenomenon and systemic sclerosis
    • Herrick AL, Illingworth K, Blann A, et al.: Von Willebrand factor, thrombomodulin, thromboxane, beta-thromboglobulin and markers of fibrinolysis in primary Raynaud's phenomenon and systemic sclerosis. Ann Rheum Dis 1996, 55:122-127.
    • (1996) Ann Rheum Dis , vol.55 , pp. 122-127
    • Herrick, A.L.1    Illingworth, K.2    Blann, A.3
  • 21
    • 0035044983 scopus 로고    scopus 로고
    • Von Willebrand factor propeptide as a marker of disease activity in systemic sclerosis (scleroderma)
    • Scheja A, Akesson A, Geborek P, et al.: Von Willebrand factor propeptide as a marker of disease activity in systemic sclerosis (scleroderma). Arthritis Res 2001, 3:178-182.
    • (2001) Arthritis Res , vol.3 , pp. 178-182
    • Scheja, A.1    Akesson, A.2    Geborek, P.3
  • 22
    • 14944346766 scopus 로고    scopus 로고
    • Screening for pulmonary hypertension in systemic sclerosis: The longitudinal development of tricuspid gradient in 227 consecutive patients, 1992-2001
    • Hesselstrand R, Ekman R, Eskilsson J, et al.: Screening for pulmonary hypertension in systemic sclerosis: the longitudinal development of tricuspid gradient in 227 consecutive patients, 1992-2001. Rheumatology (Oxford) 2005, 44:366-371.
    • (2005) Rheumatology (Oxford) , vol.44 , pp. 366-371
    • Hesselstrand, R.1    Ekman, R.2    Eskilsson, J.3
  • 23
    • 0028029736 scopus 로고
    • Circulating endothelin-1 levels in systemic sclerosis subsets - A marker of fibrosis or vascular dysfunction?
    • Vancheeswaran R, Magoulas T, Efrat G, et al.: Circulating endothelin-1 levels in systemic sclerosis subsets-a marker of fibrosis or vascular dysfunction? J Rheumatol 1994, 21:1838-1844.
    • (1994) J Rheumatol , vol.21 , pp. 1838-1844
    • Vancheeswaran, R.1    Magoulas, T.2    Efrat, G.3
  • 24
    • 0026439371 scopus 로고
    • Significance of plasma endothelin-1 levels in patients with systemic sclerosis
    • Yamane K, Miyauchi T, Suzuki N, et al.: Significance of plasma endothelin-1 levels in patients with systemic sclerosis. J Rheumatol 1992, 19:1566-1571.
    • (1992) J Rheumatol , vol.19 , pp. 1566-1571
    • Yamane, K.1    Miyauchi, T.2    Suzuki, N.3
  • 25
    • 0028520783 scopus 로고
    • Increased levels of endothelin-1 in bronchoalveolar lavage fluid from patients with systemic sclerosis contribute to fibroblast mitogenic activity in vitro
    • Cambrey AD, Harrison NK, Dawes KE, et al.: Increased levels of endothelin-1 in bronchoalveolar lavage fluid from patients with systemic sclerosis contribute to fibroblast mitogenic activity in vitro. Am J Respir Cell Mol Biol 1994, 11:439-445.
    • (1994) Am J Respir Cell Mol Biol , vol.11 , pp. 439-445
    • Cambrey, A.D.1    Harrison, N.K.2    Dawes, K.E.3
  • 26
    • 17544370003 scopus 로고    scopus 로고
    • Soluble adhesion molecules (sVCAM-1, sE-selectin), vascular endothelial growth factor (VECF) and endothelin-1 in patients with systemic sclerosis: Relationship to organ systemic involvement
    • Kuryliszyn-Moskal A, Klimiuk PA, Sierakowski S: Soluble adhesion molecules (sVCAM-1, sE-selectin), vascular endothelial growth factor (VECF) and endothelin-1 in patients with systemic sclerosis: relationship to organ systemic involvement. Clin Rheumatol 2005, 24:111-116.
    • (2005) Clin Rheumatol , vol.24 , pp. 111-116
    • Kuryliszyn-Moskal, A.1    Klimiuk, P.A.2    Sierakowski, S.3
  • 27
    • 11144357438 scopus 로고    scopus 로고
    • Circulating endothelial cells as a marker of ongoing vascular disease in systemic sclerosis
    • Del Papa N, Colombo G, Fracchiolla N, et al.: Circulating endothelial cells as a marker of ongoing vascular disease in systemic sclerosis. Arthritis Rheum 2004, 50:1296-1304. This study examined circulating endothelial cells as a potential marker of vascular damage and circulating endothelial progenitor cells as an indicator of vasculogenesis. Levels of both were noted to be elevated in scleroderma patients.
    • (2004) Arthritis Rheum , vol.50 , pp. 1296-1304
    • Del Papa, N.1    Colombo, G.2    Fracchiolla, N.3
  • 28
    • 34247564964 scopus 로고    scopus 로고
    • Angiogenic and angiostatic factors in systemic sclerosis: Increased levels of vascular endothelial growth factor are a feature of the earliest disease stages and are associated with the absence of fingertip ulcers
    • Distler O, Del Rosso A, Giacomelli R, et al.: Angiogenic and angiostatic factors in systemic sclerosis: increased levels of vascular endothelial growth factor are a feature of the earliest disease stages and are associated with the absence of fingertip ulcers. Arthritis Res 2002, 4:R11. Cross-sectional study of multiple regulators of angiogenesis, with correlation with clinical features.
    • (2002) Arthritis Res , vol.4
    • Distler, O.1    Del Rosso, A.2    Giacomelli, R.3
  • 29
    • 0034780234 scopus 로고    scopus 로고
    • Systemic sclerosis-related Raynaud's phenomenon: Effects of iloprost infusion therapy on serum cytokine, growth factor and soluble adhesion molecule levels
    • Mittag M, Beckheinrich P, Haustein UF: Systemic sclerosis-related Raynaud's phenomenon: effects of iloprost infusion therapy on serum cytokine, growth factor and soluble adhesion molecule levels. Acta Derm Venereol 2001, 81:294-297.
    • (2001) Acta Derm Venereol , vol.81 , pp. 294-297
    • Mittag, M.1    Beckheinrich, P.2    Haustein, U.F.3
  • 30
    • 0038166874 scopus 로고    scopus 로고
    • Elevated vascular endothelial growth factor in systemic sclerosis
    • Choi JJ, Min DJ, Cho ML, et al.: Elevated vascular endothelial growth factor in systemic sclerosis. J Rheumatol 2003, 30:1529-1533.
    • (2003) J Rheumatol , vol.30 , pp. 1529-1533
    • Choi, J.J.1    Min, D.J.2    Cho, M.L.3
  • 31
    • 33750343192 scopus 로고    scopus 로고
    • Evidence for abnormal angiogenesis in scleroderma patients
    • Hummers LK, Wigley FM, Simons M: Evidence for Abnormal Angiogenesis in Scleroderma Patients. Arthritis Rheum 2004, 50(Suppl 9):S630.
    • (2004) Arthritis Rheum , vol.50 , Issue.SUPPL. 9
    • Hummers, L.K.1    Wigley, F.M.2    Simons, M.3
  • 32
    • 0036731985 scopus 로고    scopus 로고
    • Expression of hepatocyte growth factor and its receptor (c-met) in skin fibroblasts from patients with systemic sclerosis
    • Kawaguchi Y, Harigai M, Hara M, et al.: Expression of hepatocyte growth factor and its receptor (c-met) in skin fibroblasts from patients with systemic sclerosis. J Rheumatol 2002, 29:1877-1883.
    • (2002) J Rheumatol , vol.29 , pp. 1877-1883
    • Kawaguchi, Y.1    Harigai, M.2    Hara, M.3
  • 33
    • 0742306757 scopus 로고    scopus 로고
    • Hepatocyte growth factor both prevents and ameliorates the symptoms of dermal sclerosis in a mouse model of scleroderma
    • Wu MH, Yokozeki H, Takagawa S, et al.: Hepatocyte growth factor both prevents and ameliorates the symptoms of dermal sclerosis in a mouse model of scleroderma. Gene Ther 2004, 11:170-180.
    • (2004) Gene Ther , vol.11 , pp. 170-180
    • Wu, M.H.1    Yokozeki, H.2    Takagawa, S.3
  • 34
    • 3042511472 scopus 로고    scopus 로고
    • Therapeutic angiogenesis using hepatocyte growth factor (HGF)
    • Morishita R, Aoki M, Hashiya N, et al.: Therapeutic angiogenesis using hepatocyte growth factor (HGF). Curr Gene Ther 2004, 4:199-206.
    • (2004) Curr Gene Ther , vol.4 , pp. 199-206
    • Morishita, R.1    Aoki, M.2    Hashiya, N.3
  • 35
    • 0033850755 scopus 로고    scopus 로고
    • Increased cocentrations of the circulating angiogenesis inhibitor endostatin in patients with systemic sclerosis
    • Hebbar M, Peyrat JP, Hornez L, et al.: Increased cocentrations of the circulating angiogenesis inhibitor endostatin in patients with systemic sclerosis. Arthritis Rheum 2000, 43:889-893.
    • (2000) Arthritis Rheum , vol.43 , pp. 889-893
    • Hebbar, M.1    Peyrat, J.P.2    Hornez, L.3
  • 36
    • 25644436232 scopus 로고    scopus 로고
    • Correlation of endostatin and tissue inhibitor of metalloproteinases 2 (TIMP2) serum levels with cardiovascular involvement in systemic sclerosis patients
    • Dziankowska-Bartkowiak B, Waszczykowska E, Zalewska A, Sysa-Jedrzejowska A: Correlation of endostatin and tissue inhibitor of metalloproteinases 2 (TIMP2) serum levels with cardiovascular involvement in systemic sclerosis patients. Mediators lnflamm 2005, 2005:144-149.
    • (2005) Mediators Lnflamm , vol.2005 , pp. 144-149
    • Dziankowska-Bartkowiak, B.1    Waszczykowska, E.2    Zalewska, A.3    Sysa-Jedrzejowska, A.4
  • 37
    • 4143072810 scopus 로고    scopus 로고
    • Defective vasculogenesis in systemic sclerosis
    • Kuwana M, Okazaki Y, Yasuoka H, et al.: Defective vasculogenesis in systemic sclerosis. Lancet 2004, 364:603-610. This study also examined circulating endothelial progenitor cells and found that these cells were lower among scleroderma patients and that they had less ability to differentiate into endothelial cells. This suggests that defective vascular repair mechanisms may contribute to scleroderma vascular disease.
    • (2004) Lancet , vol.364 , pp. 603-610
    • Kuwana, M.1    Okazaki, Y.2    Yasuoka, H.3
  • 38
    • 0036897408 scopus 로고    scopus 로고
    • Increased circulating concentrations of the counteradhesive proteins SPARC and thrombospondin-1 in systemic sclerosis (scleroderma). Relationship to platelet and endothelial cell activation
    • Macko RF, Gelber AC, Young BA, et al.: Increased circulating concentrations of the counteradhesive proteins SPARC and thrombospondin-1 in systemic sclerosis (scleroderma). Relationship to platelet and endothelial cell activation. J Rheumatol 2002, 29:2565-2570.
    • (2002) J Rheumatol , vol.29 , pp. 2565-2570
    • Macko, R.F.1    Gelber, A.C.2    Young, B.A.3
  • 39
    • 0020046233 scopus 로고
    • Elevated levels of circulating platelet aggregates and beta-thromboglobulin in scleroderma
    • Kahaleh MB, Osborn I, Leroy EC: Elevated levels of circulating platelet aggregates and beta-thromboglobulin in scleroderma. Ann Intern Med 1982, 96:610-913.
    • (1982) Ann Intern Med , vol.96 , pp. 610-913
    • Kahaleh, M.B.1    Osborn, I.2    Leroy, E.C.3
  • 40
    • 14144253440 scopus 로고    scopus 로고
    • Beta thromboglobulin and platelet factor 4 in bronchoalveolar lavage fluid of patients with systemic sclerosis
    • Kowal-Bielecka O, Kowal K, Lewszuk A, et al.: Beta thromboglobulin and platelet factor 4 in bronchoalveolar lavage fluid of patients with systemic sclerosis. Ann Rheum Dis 2005, 64:484-486.
    • (2005) Ann Rheum Dis , vol.64 , pp. 484-486
    • Kowal-Bielecka, O.1    Kowal, K.2    Lewszuk, A.3
  • 41
    • 0027276083 scopus 로고
    • Increased whole blood platelet aggregation in patients with Raynaud's phenomenon with or without systemic sclerosis
    • Lau CS, McLaren M, Saniabadi A, Belch JJ: Increased whole blood platelet aggregation in patients with Raynaud's phenomenon with or without systemic sclerosis. Scand J Rheumatol 1993, 22:97-101.
    • (1993) Scand J Rheumatol , vol.22 , pp. 97-101
    • Lau, C.S.1    McLaren, M.2    Saniabadi, A.3    Belch, J.J.4
  • 42
    • 0025719259 scopus 로고
    • The effects of thromboxane receptor blockade on platelet aggregation and digital skin blood flow in patients with secondary Raynaud's syndrome
    • Lau CS, Khan F, McLaren M, et al.: The effects of thromboxane receptor blockade on platelet aggregation and digital skin blood flow in patients with secondary Raynaud's syndrome. Rheumatol Int 1991, 11:163-168.
    • (1991) Rheumatol Int , vol.11 , pp. 163-168
    • Lau, C.S.1    Khan, F.2    McLaren, M.3
  • 43
    • 0023757187 scopus 로고
    • Increased platelet sensitivity to collagen-induced aggregation in whole blood patients with systemic sclerosis
    • Goodfield MJ, Orchard MA, Rowell NR: Increased platelet sensitivity to collagen-induced aggregation in whole blood patients with systemic sclerosis. Clin Exp Rheumatol 1988, 6:285-288.
    • (1988) Clin Exp Rheumatol , vol.6 , pp. 285-288
    • Goodfield, M.J.1    Orchard, M.A.2    Rowell, N.R.3
  • 44
    • 0024355791 scopus 로고
    • Depressed plasma fibrinolytic activity in a group of patients with connective tissue diseases
    • Munkvad S, Gram J, Jespersen J: Depressed plasma fibrinolytic activity in a group of patients with connective tissue diseases. Scand J Rheumatol 1989, 18:277-282.
    • (1989) Scand J Rheumatol , vol.18 , pp. 277-282
    • Munkvad, S.1    Gram, J.2    Jespersen, J.3
  • 45
    • 0344511824 scopus 로고    scopus 로고
    • Blood coagulation, fibrinolysis, and markers of endothelial dysfunction in systemic sclerosis
    • Cerinic MM, Valentini G, Sorano GG, et al.: Blood coagulation, fibrinolysis, and markers of endothelial dysfunction in systemic sclerosis. Semin Arthritis Rheum 2003, 32:285-295. Comprehensive look at a cross section of markers of impaired fibrinolysis, endothelial cell activation, and the coagulation cascade.
    • (2003) Semin Arthritis Rheum , vol.32 , pp. 285-295
    • Cerinic, M.M.1    Valentini, G.2    Sorano, G.G.3
  • 46
    • 0030725625 scopus 로고    scopus 로고
    • The coagulation/fibrinolysis balance in systemic sclerosis: Evidence for a haematological stress syndrome
    • Ames PR, Lupoli S, Alves J, et al.: The coagulation/fibrinolysis balance in systemic sclerosis: evidence for a haematological stress syndrome. Br J Rheumatol 1997, 36:1045-1550.
    • (1997) Br J Rheumatol , vol.36 , pp. 1045-1550
    • Ames, P.R.1    Lupoli, S.2    Alves, J.3
  • 47
    • 0035098516 scopus 로고    scopus 로고
    • The emerging problem of oxidative stress and the role of antioxidants in systemic sclerosis
    • Herrick AL, Matucci Cerinic M: The emerging problem of oxidative stress and the role of antioxidants in systemic sclerosis. Clin Exp Rheumatol 2001, 19:4-8.
    • (2001) Clin Exp Rheumatol , vol.19 , pp. 4-8
    • Herrick, A.L.1    Matucci Cerinic, M.2
  • 48
    • 0014483819 scopus 로고
    • Pathologic observations in systemic sclerosis (scleroderma). A study of fifty-eight autopsy cases and fifty-eight matched controls
    • D'Angelo WA, Fries JF, Masi AT, Shulman LE: Pathologic observations in systemic sclerosis (scleroderma). A study of fifty-eight autopsy cases and fifty-eight matched controls. Am J Med 1969, 46:428-440.
    • (1969) Am J Med , vol.46 , pp. 428-440
    • D'Angelo, W.A.1    Fries, J.F.2    Masi, A.T.3    Shulman, L.E.4
  • 49
    • 0035816729 scopus 로고    scopus 로고
    • Redox regulation of vascular smooth muscle cell differentiation
    • Su B, Mitra S, Gregg H, et al.: Redox regulation of vascular smooth muscle cell differentiation. Circ Res 2001, 89:39-46.
    • (2001) Circ Res , vol.89 , pp. 39-46
    • Su, B.1    Mitra, S.2    Gregg, H.3
  • 50
    • 0033857245 scopus 로고    scopus 로고
    • Abnormalities of erythrocyte membrane fluidity, lipid composition, and lipid peroxidation in systemic sclerosis: Evidence of free radical-mediated injury
    • Solans R, Motta C, Sola R, et al.: Abnormalities of erythrocyte membrane fluidity, lipid composition, and lipid peroxidation in systemic sclerosis: evidence of free radical-mediated injury. Arthritis Rheum 2000, 43:894-900.
    • (2000) Arthritis Rheum , vol.43 , pp. 894-900
    • Solans, R.1    Motta, C.2    Sola, R.3
  • 52
    • 0031761169 scopus 로고    scopus 로고
    • 8-Isoprostane as a biomarker of oxidative stress in interstitial lung diseases
    • Montuschi P, Ciabattoni G, Paredi P, et al.: 8-Isoprostane as a biomarker of oxidative stress in interstitial lung diseases. Am J Respir Crit Care Med 1998, 158:1524-1527.
    • (1998) Am J Respir Crit Care Med , vol.158 , pp. 1524-1527
    • Montuschi, P.1    Ciabattoni, G.2    Paredi, P.3
  • 53
    • 0029946665 scopus 로고    scopus 로고
    • Evidence of free radical-mediated injury (isoprostane overproduction) in scleroderma
    • Stein CM, Tanner SB, Awad JA, et al.: Evidence of free radical-mediated injury (isoprostane overproduction) in scleroderma. Arthritis Rheum 1996, 39:1146-1150.
    • (1996) Arthritis Rheum , vol.39 , pp. 1146-1150
    • Stein, C.M.1    Tanner, S.B.2    Awad, J.A.3
  • 54
    • 32844459573 scopus 로고    scopus 로고
    • Levels of F2-isoprostanes in systemic sclerosis: Correlation with clinical features
    • In press
    • Volpe A, Biasi D, Caramaschi P, et al.: Levels of F2-isoprostanes in systemic sclerosis: correlation with clinical features. Rheumatology (Oxford) 2005, In press.
    • (2005) Rheumatology (Oxford)
    • Volpe, A.1    Biasi, D.2    Caramaschi, P.3
  • 55
    • 32844461517 scopus 로고    scopus 로고
    • Abnormal exhaled ethane concentrations in scleroderma
    • In press
    • Cope KA, Hummers LK, Wigley FM, et al.: Abnormal exhaled ethane concentrations in scleroderma. Biomarkers 2006, In press.
    • (2006) Biomarkers
    • Cope, K.A.1    Hummers, L.K.2    Wigley, F.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.