Impracticalities of thiopurine S-methyltransferase determination in daily inflammatory bowel disease practice [5]

Alimentary Pharmacology and Therapeutics

Volumn 23, Issue 8, 2006, Pages 1278-1279

  De Boer, N K H ^a   Mulder, C J J ^a   Van Bodegraven, A A ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; MERCAPTOPURINE; THIOPURINE METHYLTRANSFERASE; TIOGUANINE;

BONE MARROW TOXICITY; COST EFFECTIVENESS ANALYSIS; CROHN DISEASE; DRUG METABOLISM; ENTERITIS; ENZYME ACTIVITY; ENZYME ASSAY; GENETIC SCREENING; GENOTYPE; HUMAN; LETTER; LEUKOPENIA; LIVER TOXICITY; MEDICAL PRACTICE; PHARMACOGENETICS; PRIORITY JOURNAL; ULCERATIVE COLITIS;

COST-BENEFIT ANALYSIS; GENOTYPE; HUMANS; INFLAMMATORY BOWEL DISEASES; METHYLTRANSFERASES; NETHERLANDS; PATIENT SELECTION;

EID: 33646883263     PISSN: 02692813     EISSN: 13652036     Source Type: Journal    
DOI: 10.1111/j.1365-2036.2006.02831.x     Document Type: Letter

References (6)

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2. Kitiyakara T Hayat J McIntyre AS. Cost-effectiveness of thiopurine methyltransferase genotype screening in IBD. Aliment Pharmacol Ther 2005 21 : 790 1.
3. Al Hadithy AF de Boer NK Derijks LJ Escher JC Mulder CJ Brouwers JR. Thiopurines in inflammatory bowel disease: pharmacogenetics, therapeutic drug monitoring and clinical recommendations. Dig Liver Dis 2005 37 : 282 97.
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5. Dubinsky MC Lamothe S Yang HY, et al. Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease. Gastroenterology 2000 118 : 705 13.
6. Derijks LJ Gilissen LP Engels LG, et al. Pharmacokinetics of 6-mercaptopurine in patients with inflammatory bowel disease: implications for therapy. Ther Drug Monit 2004 26 : 311 8.