Structural analogues of reactive intermediates as inhibitors of glucosamine-6-phosphate synthase and phosphoglucose isomerase

Archives of Biochemistry and Biophysics

Volumn 450, Issue 1, 2006, Pages 39-49

  Milewski, Sławomir ^a   Janiak, Agnieszka ^a   Wojciechowski, Marek ^a  

^a GDANSK UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

Glucosamine 6 phosphate synthase; Molecular modeling; Phosphoglucose isomerase; Transition state intermediate

Indexed keywords

2 AMINO 2 DEOXY DEXTRO GLUCITOL 6 PHOSPHATE; 2 AMINO 2 DEOXY DEXTRO MANNITOL 6 PHOSPHATE; 5 PHOSPHOARABINOATE; 6 PHOSPHOGLUCONIC ACID; ARGININE; CARBON; DEXTRO HEXITOL 6 PHOSPHATE; ENZYME INHIBITOR; FUNGAL ENZYME; GLUCOSAMINE 6 PHOSPHATE SYNTHASE INHIBITOR; GLUCOSE 6 PHOSPHATE ISOMERASE INHIBITOR; GLUTAMINE; GLUTAMINE FRUCTOSE 6 PHOSPHATE AMINOTRANSFERASE; LYSINE; NITROGEN; PHOSPHOARABINOATE; UNCLASSIFIED DRUG; VALINE;

ACETYLATION; ARTICLE; CHEMICAL BOND; ELECTRICITY; ENZYME BINDING; ENZYME INHIBITION; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; RABBIT; STRUCTURE ANALYSIS;

AMINO ACIDS; ANIMALS; BINDING SITES; CATALYTIC DOMAIN; ENZYME INHIBITORS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GLUCOSE-6-PHOSPHATE ISOMERASE; GLUTAMINE-FRUCTOSE-6-PHOSPHATE TRANSAMINASE (ISOMERIZING); KINETICS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RABBITS; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP;

ESCHERICHIA COLI; ORYCTOLAGUS CUNICULUS;

EID: 33646882795     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2006.03.019     Document Type: Article

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