Uncoupling the relationship between fatty acids and longevity

IUBMB Life

Volumn 58, Issue 3, 2006, Pages 153-155

  Kua, Chong Han ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Aging; Fatty acids; Reactive oxygen species; Uncoupling

Indexed keywords

FATTY ACID; REACTIVE OXYGEN METABOLITE; UNCOUPLING PROTEIN;

AGING; ARTICLE; CALORIC RESTRICTION; CORRELATION ANALYSIS; FOWL; HUMAN; LONGEVITY; MAMMAL; MEDICAL RESEARCH; NONHUMAN; OXIDATION; SPECIES COMPARISON; STRESS; UPREGULATION;

AGING; ANIMALS; FATTY ACIDS; HUMANS; LONGEVITY; REACTIVE OXYGEN SPECIES;

AVES; MAMMALIA;

EID: 33646881333     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1080/15216540600644812     Document Type: Article

References (28)

1. Sastre, J., Pallardo, F. V., and Vina, J. (2000) Mitochondrial oxidative stress plays a key role in aging and apoptosis. IUBMB Life 49, 427-435.
2. Barja, G. (2002) Rate of generation of oxidative stress-related damage and animal longevity. Free Radic. Biol. Med. 33, 1167-1172.
3. Harman, D. (1994) Aging: prospects for further increases in the functional lifespan. Age 17, 119-146.
4. Beal, M. F. (2002) Oxidatively modified proteins in aging and disease. Free Radic. Biol. Med. 32, 797-803.
5. Sohal, R. S., and Weindruch, R., (1996) Oxidative stress, caloric restriction, and aging. Science 273, 59-63.
6. Sohal, R. S., Ku, H. H., Agarwal, S., Forster, M. J., and Lal, H. (1994) Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse. Mech. Ageing Dev. 74, 121-133.
7. Merry, B. J. (2004) Oxidative stress and mitochondrial function with aging - the effects of calorie restriction. Aging Cell 3, 7-12.
8. Skulachev, V. P. (1996) Role of uncoupled and non-coupled oxidations in maintenance of safely low levels of oxygen and its one-electron reductants. Q. Rev. Biophys. 29, 169-202.
9. Ricquier, D., and Bouillaud, F. (2000) The uncoupling protein homologues: UCP1, UCP2, UCP3, StUCP and AtUCP. Biochem. J. 345, 161-179.
10. Xiao, H., Massaro, D., Massaro, G. D., and Clerch, L. B. (2004) Expression of lung uncoupling protein-2 mRNA is modulated developmentally and by caloric intake. Exp. Biol. Med. 229, 479-485.
11. Arsenijevic, D., Onuma, H., Pecqueur, C., Raimbault, S., Manning, B. S., Miroux, B., Couplan, E., Alves-Guerra, M. C., Goubern, M., Surwit, R., Bouillaud, F., Richard, D., Collins, S., and Ricquier, D. (2000) Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production. Nat. Genet. 26, 435-439.
12. Goglia, F., and Skulachev, V. P. (2003) A function for novel uncoupling proteins: antioxidant defense of mitochondrial matrix by translocating fatty acid peroxides from the inner to the outer membrane leaflet. FASEB J. 17, 1585-1591.
13. Wolfrum, C., Asilmaz, E., Luca, E., Friedman, J. M., and Stoffel, M. (2004) Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes. Nature 432, 1027-1032.
14. Lombardi, A., Silvestri, E., Moreno, M., De Lange, P., Farina, P., Goglia, F., and Lanni, A. (2002) Skeletal muscle mitochondrial free-fatty-acid content and membrane potential sensitivity in different thyroid states: involvement of uncoupling protein-3 and adenine nucleotide translocase. FEBS Lett. 532, 12-16.
15. Skulachev, V. P. (1999) Anion carriers in fatty acid-mediated physiological uncoupling. J. Bioenerg. Biomembr. 5, 431-445.
16. + transport activity of the reconstituted uncoupling protein. J. Biol. Chem. 269, 2508-2515.
17. Khosla, P., and Sundram, K. (1996) Effects of dietary fatty acid composition on plasma cholesterol. Prog. Lipid Res. 35, 93-132.
18. Snook, J. T., Park, S., Williams, G., Tsai, Y-H., and Lee, N. (1999) Effect of synthetic triglycerides of myristic, palmitic, and stearic acid on serum lipoprotein metabolism. Eur. J. Clin. Nutr. 53, 597-605.
19. Skulachev, V. P. (1998) Uncoupling: new approaches to an old problem of bioenergetics. Biochim. Biophys. Acta 1363, 100-124.
20. 2 by mitochondria in the resting state. FEBS Lett. 435, 215-218.
21. Pastore, D., Fratianni, A., Di Pede, S., and Passarella, S. (2000) Effects of fatty acids, nucleotides and reactive oxygen species on durum wheat mitochondria. FEBS Lett. 470, 88-92.
22. Casolo, V., Braidot, E., Chiandussi, E., Macri, F., and Vianello, A. (2000) The role of mild uncoupling and non-coupled respiration in the regulation of hydrogen peroxide generation by plant mitochondria. FEBS Lett. 474, 53-57.
23. Vettor, R., Fabris, R., Serra, R., Lombardi, A. M., Tonello, C., Granzotto, M., Marzolo, M. O., Carruba, M. O., Ricquier, D., Federspil, G., and Nisoli, E. (2002) Changes in FAT/CD36, UCP2, UCP3 and GLUT4 gene expression during lipid infusion in rat skeletal and heart muscle. Int. J. Obes. Relat. Metab. Disord. 26, 838-847.
24. 2 production of heart mitochondria and aging rate are slower in canaries and parakeets than in mice: sites of free radical generation and mechanisms involved. Mech. Ageing Dev. 103, 133-146.
25. Speakman, J. R., Talbot, D. A., Selman, C., Snart, S., McLaren, J. S., Redman, P., Krol, E., Jackson, D. M., Johnson, M. S., and Brand, M. D. (2004) Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longer. Aging Cell 3, 87-95.
26. Vianna, C. R., Hagen, T., Zhang, C. Y., Bachman, E., Boss, O., Gereben, B., Moriscot, A. S., Lowell, B. B., Bicudo, J. E., and Bianco, A. C. (2001) Cloning and functional characterization of an uncoupling protein homolog in hummingbirds. Physiol. Genomics 5, 137-145.
27. Criscuolo, F., Gonzalez-Barroso, Mdel. M., Le Maho, Y., Ricquier, D., and Bouillaud, F. (2005) Avian uncoupling protein expressed in yeast mitochondria prevents endogenous free radical damage. Proc. Biol. Sci. 272, 803-810.
28. Lee, C. K., Allison, D. B., Brand, J., Weindruch, R., and Prolla, T. A. (2002) Transcriptional profiles associated with aging and middle age-onset caloric restriction in mouse hearts. Proc. Natl. Acad. Sci. USA 99, 14988-14993.