The effect of pentoxifylline on cognitive dysfunction and mood state after open coronary revascularisation while using the heart-lung machine;Der einfluss von pentoxifyllin auf kognitive dysfunktion und befindlichkeit nach offener koronarrevaskularisation unter einsatz der herz-lungen-maschine

Anasthesiologie und Intensivmedizin

Volumn 47, Issue 5, 2006, Pages 255-263

  Bahlmann, Ludger ^a   Weber, Ch ^a   Heinrichs, G ^a   Heringlake, M ^a   Poling J ^c   Hartwig, D ^b   Hermes, D ^a   Huppe M ^a   Klaus, St ^d  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^b Institut für Immunologie und Transfusionsmedizin Lübeck   (Germany)

^c Schuchtermann Klinik   (Germany)

^d Herz Jesu Krankenhaus Munster Hiltrup   (Germany)

Author keywords

Cardiopulmonary Bypass; Cognitive Performance; Mood State; Pentoxifylline

Indexed keywords

NEURON SPECIFIC ENOLASE; PENTOXIFYLLINE; PLACEBO;

ANXIETY; APATHY; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; COGNITIVE DEFECT; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEPRESSION; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG EFFICACY; HEART LUNG MACHINE; HEART MUSCLE REVASCULARIZATION; HUMAN; MALE; MOOD DISORDER; OPEN HEART SURGERY; RANDOMIZED CONTROLLED TRIAL; SELF EVALUATION; TREATMENT OUTCOME;

EID: 33646878808     PISSN: 01705334     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Suksompong, S., et al., Neuropsychological alterations after coronary artery bypass graft surgery. J Med Assoc Thai, 2002. 85 Suppl 3: S910-6.
2. Savageau, J.A., et al., Neuropsychological dysfunction following elective cardiac operation. I. Early assessment. J Thorac Cardiovasc Surg, 1982. 84(4): 585-94.
3. Walzer, T., M. Herrmann, and C.W. Wallesch, Neuropsychological disorders after coronary bypass surgery. J Neurol Neurosurg Psychiatry, 1997. 62(6): 644-8.
4. McKhann, G.M., et al., Cognitive outcome after coronary artery bypass: a one-year prospective study. Ann Thorac Surg, 1997. 63(2): 510-5.
5. Andrew, M.J., et al., Mood state as a predictor of neuropsychological deficits following cardiac surgery. J Psychosom Res, 2000. 48(6): 537-46.
6. Asimakopoulos, G., Systemic inflammation and cardiac surgery: an update. Perfusion, 2001. 16(5): 353-60.
7. Smith, P.L., The systemic inflammatory response to cardiopulmonary bypass and the brain. Perfusion, 1996. 11(3): 196-9.
8. Taggart, D.P. and S. Westaby, Neurological and cognitive disorders after coronary artery bypass grafting. Curr Opin Cardiol, 2001. 16(5): 271-6.
9. Taggart, D.P., et al., Is cardiopulmonary bypass still the cause of cognitive dysfunction after cardiac operations? J Thorac Cardiovasc Surg, 1999. 118(3): 414-20; discussion 420-1.
10. Patel, N.C., et al., Neurological outcomes in coronary surgery: independent effect of avoiding cardiopulmonary bypass. Ann Thorac Surg, 2002. 74(2): 400-5; discussion 405-6.
11. Borger, M.A. and C.M. Feindel, Cerebral emboli during cardiopulmonary bypass: effect of perfusionist interventions and aortic cannulas. J Extra Corpor Technol, 2002. 34(1): 29-33.
12. Fearn, S.J., et al., Cerebral embolisation during modern cardiopulmonary bypass. Eur J Cardiothorac Surg, 2001. 20(6): 1163-7.
13. Passero, S., M. Nardini, and N. Battistini, Effect of pentoxifylline on cerebral blood flow in patients with chronic cerebrovascular disease. J Int Med Res, 1981, 9(3): 211-4.
14. Gey, D.C., E.P. Lesho, and J. Manngold, Management of peripheral arterial disease. Am Fam Physician, 2004. 69(3): 525-32.
15. Neuner, P., et al., Pentoxifylline in vivo down-regulates the release of IL-1 beta, IL-6, IL-8 and tumour necrosis factor-alpha by human peripheral blood mononuclear cells. Immunology, 1994. 83(2): 262-7.
16. Cagli, K., et al., The intra-operative effect of pentoxifylline on the inflammatory process and leukocytes in cardiac surgery patients undergoing cardiopulmonary bypass. Perfusion, 2005. 20(1): 45-51.
17. Koul, B.L., et al., The effect of pentoxifylline on impaired red cell deformability following open-heart surgery. Scand J Thorac Cardiovasc Surg, 1984. 18(2): 129-31.
18. Angelides, N.S. and C. Minas, Can aortocoronary and peripheral venous bypass graft patency be improved by the administration of pentoxifylline on a long-term basis? Cardiologia, 1999. 44(12): 1059-64.
19. Janke, W. and G. Debus, Die Eigenschaftswörterliste (EWL-60-S). 1978: Göttingen, Hogrefe Verlag.
20. Gerlach, K., et al., Effects of opipramol as an evening anaesthesiologic premedication. Neuropsychobiology, 2002. 46(3): 161-6.
21. Huppe, M., et al., Management and methodological approaches for the assessment of emotional states in anesthesiology. Anasthesiol Intensivmed Notfallmed Schmerzther, 2000. 35(1): 3-11.
22. Reitan, R.M., Trail-Making Test: Manual for administration, scoring and interpretation. 1956: Indianapolis.
23. Oswald, W.D., et al. On the meaning of psychometrically operationalized therapeutic effects in the treatment of brain insufficiency phenomena caused by old age demonstrated by the "Nurnberger-Alters-Inventar" (author's transl). Arzneimittelforschung, 1982. 32(5): 584-90.
24. Rasmussen, L.S., et al., Biochemical markers for brain damage after cardiac surgery - time profile and correlation with cognitive dysfunction. Acta Anaesthesiol Scand, 2002. 46(5): 547-51.
25. Ustunsoy, H., et al., The inhibition of pro-inflammatory cytokines with pentoxifylline in the cardiopulmonary bypass lung. Respir Med, 2002. 96(4): 275-9.
26. Kleinschmidt, S., et al., Pro-inflammatory cytokine gene expression in whole blood from patients undergoing coronary artery bypass surgery and its modulation by pentoxifylline. Shock, 1998. 9(1): 12-20.
27. Butler, J., et al., Systemic inflammatory responses to cardiopulmonary bypass: a pilot study of the effects of pentoxifylline. Respir Med, 1993. 87(4): 285-8.
28. Murkin, J.M., et al., Statement of consensus on assessment of neurobehavioral outcomes after cardiac surgery. Ann Thorac Surg, 1995. 59(5): 1289-95.
29. Wan, S., J.L. LeClerc, and J.L. Vincent, Inflammatory response to cardiopulmonary bypass: mechanisms involved and possible therapeutic strategies. Chest, 1997. 112(3): 676-92.
30. Taylor, K.M., Brain damage during cardiopulmonary bypass. Ann Thorac Surg, 1998. 65(4 Suppl): S20-6; discussion S27-8.
31. Parnetti, L., et al., The role of haemorheological factors in the ageing brain: long-term therapy with pentoxifylline ('Trental' 400) in elderly patients with initial mental deterioration. Pharmatherapeutica, 1986. 4(10): 617-27.
32. Hallas, C.N., et al., Predicting blood pressure reactivity and heart rate variability from mood state following coronary artery bypass surgery. Int J Psychophysiol, 2003, 47(1): 43-55.
33. Utriyaprasit, K. and S. Moore, Recovery Symptoms and Mood States in Thai CABG patients. J Transcult Nurs, 2005. 16(2): 97-106.
34. Boldt, J., et al., Prophylactic use of pentoxifylline on inflammation in elderly cardiac surgery patients. Ann Thorac Surg, 2001. 71(5): 1524-9.
35. Janke, W., Angst: Definition und somatische Grundlagen, in Angst und Psychopharmaka. 1986, Netter P. (Hrsg.) Kohlhammer Stuttgart 1986. 19-42.
36. Herrmann, M., et al., Neurobehavioral outcome prediction after cardiac surgery: role of neurobiochemical markers of damage to neuronal and glial brain tissue. Stroke, 2000. 31(3): 645-50.