The inhibition of pro-inflammatory cytokines with pentoxifylline in the cardiopulmunary bypass lung

Respiratory Medicine

Volumn 96, Issue 4, 2002, Pages 275-279

  Ustunsoy H ^a   Sivrikoz, M C ^a   Bakir, K ^b   Enkaya, I ^a   Erba G B ^b   Ucak R ^b   Nurozler F ^c  

^a Department of Cardiovascular and Thorax Surgery ^*  (Turkey)

^b GAZIANTEP UNIVERSITY   (Turkey)

^c Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Cardiopulmonary bypass; Inflammatory response; Lung; Pentoxifylline

Indexed keywords

ANTIBIOTIC AGENT; BICARBONATE; CORTICOSTEROID; CYTOKINE; INTERLEUKIN 6; INTERLEUKIN 8; MANNITOL; PENTOXIFYLLINE; RINGER LACTATE SOLUTION; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD PUMP; BLOOD SAMPLING; CARDIOPULMONARY BYPASS; CHEMOLUMINESCENCE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; HEART VENTRICLE SEPTUM DEFECT; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOASSAY; LUNG BIOPSY; MALE; OPEN HEART SURGERY; PNEUMONIA; PRIORITY JOURNAL; RANK SUM TEST; STATISTICAL SIGNIFICANCE; VALVULAR HEART DISEASE;

EID: 0036553573     PISSN: 09546111     EISSN: None     Source Type: Journal    
DOI: 10.1053/rmed.2001.1255     Document Type: Article

References (17)

1. Kleinschmidt S, Baver M, Grundmann U, Schmeider A, Wagner B, Graeter T. Effect of gamma-hydroxybutyric acid and pentoxifylline on kidney function parameters in coronary surgery interventions. Anaesthesiol Reanim 1997; 22: 102-107.
2. Pridjian AK, Bove EL, Bolling SF, Childs KF, Brosamer KM, Lupinetti FM. Developmental differences in myocardial protection in response to 5′-nucleotidase inhibition. J Thorac Cardiovasc Surg 1994; 107: 520-526.
3. Bolling SF, Olszanski DA, Bove EL, Childs KF. Enhanced myocardial protection during global ischemia with 5′-nucleotidase inhibitors. J Thorac Cardiovasc Surg 1992; 103: 73-77.
4. Grisham MB, Granger N. Metabolic sources of reactive oxygen metabolites during oxidant stress and ischemia with reperfusion. Clin Chest Med 1989; 10: 71-81.
5. Farber JL. Membrane injury and calcium homeostasis in the pathogenesis of coagulative necrosis. Lab Invest 1982; 47: 114-123.
6. Tauber AI, Babior BM. Neutrophil oxygen reduction: The enzymes and the products. Adv Free Rad Biol Med 1985; 1: 265.
7. Hayashi Y, Sawa Y, Nishimura M, Tojo ST, Ichikawa H, Satoh H, et al. P-selection monoclonal antibody may attenuate the whole body inflammatory response induced by cardiopulmonary bypass. ASAIO J 2000; 46: 334-337.
8. Jamieson D, Chance B, Ladeas E, Boveris A. The relation of free radical production to hyperoxia. Annu Rev Physiol 1986; 48: 703-719.
9. Ossanna PJ, Test ST, Matheson NR, Regiani S, Weiss SJ. Oxidative regulation of neutrophil elastase-alpha-proteinase inhibitor interactions. J Clin Invest 1986; 77: 1939-1951.
10. Weiss SJ, Peppin G, Ortiz X, Ragsdale C, Test ST. Oxidative autoactivation of latent collagenase by human neutrophils. Science 1985; 227: 747-749.
11. Sullivan GW, Carper HT, Novick WJ, Mandell GL. Inhibition of the inflamatory action of interleukin-1 and tumor necrosis factor (alpha) on neutrophil function by pentoxifylline. Infect Immun 1998; 56: 1722-1729.
12. Gomez-Cambranero L, Camps B, de La Asuncion JG, et al. Pentoxifylline ameliorates cerulein-induced pancreatitis in rats: role of glutathione and nitric oxide. J Pharmacol Exp Ther 2000; 293: 670-676.
13. Olszanski DA, Ning Xuc-Han, Childs KF, Bolling SF. Precursor trapping: A 'Neonatal' mechanism of myocardial protection. J Surg Research 1993; 54: 539-544.
14. Yoshiki S, Yasuhisa S, Keishi K, Takashi M, Hirotsugu F. Attenuation of cardiopulmonary bypass-derived inflammatory reactions reduces myocardial reperfusion injury in cardiac operations. J Thorac Cardiovasc Surg 1996; III: 29-35.
15. Cain BS, Meldrum DR, Dinarello CA, Meng X, Banerjee A, Harken AH. Adenosine reduces cardiac TNFα production and human myocardial injury following ischemia-reperfusion. J Surg Res 1998; 76: 117-123.
16. Kirklin JW, Barratt-Boyes BG. Hypotermia. Circulatory arrest and cardiopulmonary bypass. In: Kirklin JW, Barratt-Boyes BG, ed. Cardiac Surgery. New York: Churchill Livingstone, 1993.
17. Türköz R, Yörükoǧlu K, Akçay A, et al. The effect of pentoxifylline on the lung during cardiopulmonary bypass. Eur J Cardiothorac Surg 1996; 10: 339-346.