Syntheses, characterization and antitumour activities of rare earth metal complexes with 2-(((4,6-dimethyl)-2-Pyrimidinyl)thio)-acetic acid

Journal of Rare Earths

Volumn 24, Issue 1, 2006, Pages 15-19

  Qu, Jianqiang ^a,b   Wang, Liufang ^a   Liu, Yingqi ^a   Song, Yumin ^c   Wang, Yinyue ^a   Jia, Xiaofei ^b  

^a LANZHOU UNIVERSITY   (China)

^b TIANJIN UNIVERSITY   (China)

^c NORTHWEST NORMAL UNIVERSITY   (China)

Author keywords

2 (((4,6 dimethyl) 2 pyrimidinyl)thio) acetic acid; Anti tumour activities; Complexes; Rare earths

Indexed keywords

ACETIC ACID; CHARACTERIZATION; PHYSICAL PROPERTIES; RARE EARTHS; SPECTRUM ANALYSIS; STABILITY; SYNTHESIS (CHEMICAL); TESTING; TUMORS;

ANTITUMOUR ACTIVITIES; RARE EARTH METAL COMPLEXES; SUPPRESSION RATIOS;

COMPLEXATION;

EID: 33646873775     PISSN: 10020721     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1002-0721(06)60057-4     Document Type: Article

References (27)

1. Kreutzberger A, Tesch U H. Antimycotic drugs. 5th communication: carbocyclically and heterocyclically substituted trifluoromethylpyrimidines[J]. Drug Res., 1978, 28(2): 235.
2. Matteson D S, Biernbaum M S, Bechtold R A, et al. Synthesis of boron-substituted pyrimidines and borazaroquinazolines[J]. J. Org. Chem., 1978, 43(5): 950.
3. Goodgane D M L, Jeeves I, Leach G A. Complexes of 4,6-dimethylpyrimidine-2-thione with some divalent metal ions[J]. Inorg. Chim. Acta, 1980, 39: 247.
4. Sen A B, Kapoor G N. Search for potential antitumour compounds. Part IX.[J]. J. Indian Chem. Soc., 1973, 50(7): 486.
5. Bruce G O, Stephen D R. Complexes of the platinum metal part 35. 4,6-dimethylpyrimidine-2-thiol derivatives of ruhenium, osmium, rhodium and iridium[J]. Inorg. Chim. Acta, 1989, 165: 153.
6. Nigam S C, Saharia G S, Sharma H R. Studies in heterocyclic compounds. Part-XXXV III: Synthesis and in vitro screening of 4,6-dimethyl-5-(arylazo/N-substituted p-sulphamylbenzeneazo) pyrimidin-2-thiols[J]. J. Indian Chem. Soc., 1983, 60(6): 583.
7. Mao Manjun, Chen Yaozu, Tian Xuan. Synthesis and antitumor activity of new heterocyclic 5-fluorouracil derivatives[J]. Acta Pharm. Sinica (in Chin.), 1998, 33(5): 389.
8. Liu Huixue, Yang Xiaoda, Wang Kui. Effect of lan-thanium on proliferation and protein expression of liver cell line 7701[J]. Journal of the Chinese Rare Earth Society (in Chin.), 2004, 22(4): 434.
9. Li Rongchang, Yang Xiaoda, Wang Kui, et al. Research progress of bioinorganic chemistry of rare earths[J]. Journal of the Chinese Rare Earth Society (in Chin.), 2004, 22(1): 1.
10. Zhang Weiguang, Yin Xia, Fan Jun. Progress in synthesis and application of complexes of rare earth with organic ligands containing sulphur atoms[J]. Journal of the Chinese Rare Earth Society (in Chin.), 2004, 22(3): 299.
11. Li Rongchang, Yang Liuchun, Wang Kui. Interactions between rare earth ions and human erythrocyte spectrin[J]. Journal of the Chinese Rare Earth Society (in Chin.), 2004, 22(1): 145.
12. An Yi, Li Rongchang, Wang Kui. Effects of rare earth element on proliferation of human hepatoma cell SMMC27721[J]. Journal of the Chinese Rare Earth Society (in Chin.), 2005, 23(1): 105.
13. Li Jinzhou, Jiang Li, An Yumei. Synthesis of acylpyrazolone-amino-acid schiff base rare earth complexes and its bioactivity[J]. Journal of the Chinese Rare Earth Society (in Chin.), 2004, 22(2): 189.
14. Jiang Wenhua, Chen Dong, Meng Xiaoting, et al. Inhibitive effect and mechanism of lanthanum nitrate on preneoplastic lesion in rat liver[J]. Journal of the Chinese Rare Earth Society (in Chin.), 2004, 22(2): 292.
15. Li Jin, Hu Guowu, Ou Yangdi, et al. Effect of cerium on expression and activity of MMP-9 from human carcinoma of bladder cell line[J]. Journal of Rare Earths, 2004, 22(2): 288.
16. Xu Xianggui, Xia Hongtao, Rui Guang, et al. Effect of lanthanum on acid secretion from isolated mouse stomach in vitro[J]. Journal of Rare Earths, 2004, 22(3): 427.
17. Liu Hong, Zhang Huizhen, Zeng Wei, et al. Preparation of ternary lanthanide complexes with unsaturated acid and 1,10-phenanthroline, and their anti-inflammatory action[J]. Journal of Rare Earths, 2004, 22: 46.
18. Fan Juan, Shen Rui, Tang Ning. Synthesis, characterization and antioxidative activity of lanthanide complexes with genistein[J]. Journal of Rare Earths, 2004, 22: 25.
19. Ellis K J. The lanthanide elements in biochemistry, biology and medicine[J]. Inorg. Persp. Bio. Med., 1977, 1(2): 101.
20. Evans C H. Interesting and useful biochemical properties of lanthanides[J]. Trends Biochem. Sci., 1983, 8(12): 445.
21. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays[J]. J. Immuno. Meth., 1983, 65(1-2): 55.
22. Skehan P, Storeng R, Scudiero D, et al. New colorimetric cytotoxicity assay for anticancer-drug screening[J]. J. Natl. Cancer. Inst., 1990, 82(13): 1107.
23. Geary W J. The use of conductivity measurements in organic solvents for the characterization of coordination compounds[J]. Coord. Chem. Rev., 1971, 7(1): 81.
24. Shi Yaozeng, Kong Xiangzhen, Jiang Yanhao. Spectra and Chemical Identify in Organic Compounds[M]. Nanjing: Publishing House of Jiangsu Science and Technology, 1988, 111.
25. Nakamoto K. Infrared and Raman Spectra in Inorganic and Coordination Compounds[M]. New York: John Wiley, 1976. 236.
26. Khan A A, Iftikhar K. Mixed-ligand lanthanide complexes-VII. Complexes of 1,10-phenanthroline and thiocyanate[J]. Polyhedron, 1994, 13(19): 3199.
27. Bai J F, Wu J G, Wang L F, et al. Synthesis, properties, and antioxidative behavior of some transition metal complexes of N-[(benzoylamino)-thioxomethyl] glycine[J]. Synth. React. Inorg. Met.-Org. Chem., 1998, 28(6): 917.