Synthesis and antitumor activity of new heterocyclic 5-fluorouracil derivatives

Yaoxue Xuebao

Volumn 33, Issue 5, 1998, Pages 389-391

  Mao, Manjun ^a   Chen, Yaozu ^b   Tian, Xuan ^a  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^b LANZHOU UNIVERSITY   (China)

Author keywords

5 Fluorouracil; Antitumor activity; Heterocyclic compound

Indexed keywords

ANTINEOPLASTIC ANTIMETABOLITE; DRUG DERIVATIVE; FLUOROURACIL; HETEROCYCLIC COMPOUND;

ARTICLE; CELL CULTURE; CELL STRAIN KB; CHEMICAL STRUCTURE; DRUG EFFECT; HUMAN; IC 50; SYNTHESIS;

ANTIMETABOLITES, ANTINEOPLASTIC; FLUOROURACIL; HETEROCYCLIC COMPOUNDS; HUMANS; INHIBITORY CONCENTRATION 50; KB CELLS; MOLECULAR STRUCTURE; TUMOR CELLS, CULTURED;

EID: 0032056547     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (4)

1. Nigam SC, Saharia GS, Sharma HR. Studies in heterocyclic compounds. 38: Synthesis and in vitro screening of 4, 6-dimethyl-5-(arylazo/N-substituted p-sulphamylbenzeneazo) pyrimidin-2-thiols. J Indian Chem Soc, 1983, 60:583
2. Sen AB, Kapoor RN. Search for potential antitumour compounds. 9: J Indian Chem Soc, 1973, 50 :486
3. Ahmad S, Ozaki S, Nagase T, et al. A facile method for synthesis of N-acyloxymenthyl-5-fluorouracils, as a class of antitumor agents. Chem Pharm Bull, 1987, 35:4137