Molecular models of tryptophan synthase from Mycobacterium tuberculosis complexed with inhibitors

Cell Biochemistry and Biophysics

Volumn 44, Issue 3, 2006, Pages 375-384

  Bertacine Dias, Marcio Vinicius ^a   Canduri, Fernanda ^b   Freitas Da Silveira, Nelson José ^a   Czekster, Clarissa Melo ^c   Basso, Luis Augusto ^d   Palma, Mário Sérgio ^e   Santos, Diógenes Santiago ^d   De Azevedo Jr , Walter Filgueira ^d  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b FEDERAL UNIVERSITY OF MATO GROSSO DO SUL   (Brazil)

^c FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^d PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^e Institute of Biosciences   (Brazil)

Author keywords

Drug design; Molecular modeling; Mycobacterium tuberculosis; Structural bioinformatics; Tryptophan synthase

Indexed keywords

LIGAND; PATHOGENESIS RELATED PROTEINS, PLANT; PATHOGENESIS-RELATED PROTEINS, PLANT; TRYPTOPHAN SYNTHASE; VEGETABLE PROTEIN;

BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; CLASSIFICATION; COMPUTER SIMULATION; CONFERENCE PAPER; DRUG ANTAGONISM; DRUG DESIGN; ENZYME SPECIFICITY; ENZYMOLOGY; FAGACEAE; GENETICS; HYDROGEN BOND; MYCOBACTERIUM TUBERCULOSIS; PHYSIOLOGY; PROTEIN BINDING; PROTEIN CONFORMATION; ROSACEAE; SEQUENCE ALIGNMENT;

BINDING SITES; COMPUTER SIMULATION; DRUG DESIGN; FAGACEAE; HYDROGEN BONDING; LIGANDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; PLANT PROTEINS; PROTEIN BINDING; PROTEIN CONFORMATION; ROSACEAE; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY; TRYPTOPHAN SYNTHASE;

MYCOBACTERIUM TUBERCULOSIS;

EID: 33646860538     PISSN: 10859195     EISSN: None     Source Type: Journal    
DOI: 10.1385/CBB:44:3:375     Document Type: Conference Paper

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