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Volumn 11, Issue 2, 2006, Pages 100-112

Formula supplemented with docosahexaenoic acid (DHA) and arachidonic acid (ARA): A critical review of the research

Author keywords

ARA; DHA; Fatty acids; Growth; Human development; Infant; Infant feeding; Infant formula; Newborn; Nutrients; Nutrition; Supplemental

Indexed keywords

ARACHIDONIC ACID; DOCOSAHEXAENOIC ACID;

EID: 33646853723     PISSN: 15390136     EISSN: 17446155     Source Type: Journal    
DOI: 10.1111/j.1744-6155.2006.00048.x     Document Type: Article
Times cited : (17)

References (39)
  • 1
    • 0029116017 scopus 로고
    • Neurodevelopmental quotient of healthy term infants at 4 months and feeding practice: The role of long-chain polyunsaturated fatty acids
    • Agostini, C., Trojan, S., Bellu, R., Riva, E. Giovannini, M. (1995). Neurodevelopmental quotient of healthy term infants at 4 months and feeding practice: The role of long-chain polyunsaturated fatty acids. Pediatric Research, 38, 262 266.
    • (1995) Pediatric Research , vol.38 , pp. 262-266
    • Agostini, C.1    Trojan, S.2    Bellu, R.3    Riva, E.4    Giovannini, M.5
  • 2
    • 34848917355 scopus 로고    scopus 로고
    • American Academy of Pediatrics. (.). AAP: Jury still out on ARA, DHA in formula. Retrieved September 4, 2005, from
    • American Academy of Pediatrics. (2002). AAP: Jury still out on ARA, DHA in formula. Retrieved September 4, 2005, from http://aapnews.aappublication.org/ cgi/content/full/e200272v1
    • (2002)
  • 3
    • 17844392079 scopus 로고    scopus 로고
    • Growth and development in term infants fed long-chain polyunsaturated fatty acids: A double-masked, randomized, parallel, prospective, multivariate study
    • Auestad, N., Halter, R., Hall, R.T., Montalto, M.B., Jacobs, J.R., Qui, W., et al. (2001). Growth and development in term infants fed long-chain polyunsaturated fatty acids: A double-masked, randomized, parallel, prospective, multivariate study. Pediatrics, 108, 372 381.
    • (2001) Pediatrics , vol.108 , pp. 372-381
    • Auestad, N.1    Halter, R.2    Hall, R.T.3    Montalto, M.B.4    Jacobs, J.R.5    Qui, W.6
  • 4
    • 8044227779 scopus 로고    scopus 로고
    • Visual acuity, erythrocyte fatty acid composition, and growth in term infants fed formulas with long chain polyunsaturated fatty acids for 1 year. Ross Pediatric Lipid Study
    • Auestad, N., Montalto, M.B., Hall, R.T., Fitzgerald, K.M., Wheeler, R.E., Connor, W.E., et al 1997). Visual acuity, erythrocyte fatty acid composition, and growth in term infants fed formulas with long chain polyunsaturated fatty acids for 1 year. Ross Pediatric Lipid Study. Pediatric Research, 41, 1 10.
    • (1997) Pediatric Research , vol.41 , pp. 1-10
    • Auestad, N.1    Montalto, M.B.2    Hall, R.T.3    Fitzgerald, K.M.4    Wheeler, R.E.5    Connor, W.E.6    Al, E.7
  • 5
    • 18744431460 scopus 로고    scopus 로고
    • Visual, cognitive, and language assessments at 39 months: A follow-up study of children fed formulas containing long-chain polyunsaturated fatty acids to 1 year of age
    • Auestad, N., Scott, E.T., Janowsky, J.S., Jacobsen, C., Carroll, R.E., Montalto, M.B., et al 2003). Visual, cognitive, and language assessments at 39 months: A follow-up study of children fed formulas containing long-chain polyunsaturated fatty acids to 1 year of age. Pediatrics, 112, e177 183.
    • (2003) Pediatrics , vol.112
    • Auestad, N.1    Scott, E.T.2    Janowsky, J.S.3    Jacobsen, C.4    Carroll, R.E.5    Montalto, M.B.6    Al, E.7
  • 7
    • 0037177937 scopus 로고    scopus 로고
    • Prevalence of selected maternal behaviors and experiences, pregnancy risk assessment monitoring system (PRAMS), 1999
    • 21. 22.
    • Beck, L.F., Morrow, B., Lipscomb, L.E., Johnson, C.H., Gaffield, M.E., Rogers, M., et al. (2002). Prevalence of selected maternal behaviors and experiences, pregnancy risk assessment monitoring system (PRAMS), 1999. Morbidity and Mortality Weekly Report, 51, 10 18, 21 22.
    • (2002) Morbidity and Mortality Weekly Report , vol.51 , pp. 10-18
    • Beck, L.F.1    Morrow, B.2    Lipscomb, L.E.3    Johnson, C.H.4    Gaffield, M.E.5    Rogers, M.6
  • 8
    • 0034098652 scopus 로고    scopus 로고
    • A randomized controlled trial of early dietary supply of long-chain polyunsaturated fatty acids and mental development in term infants
    • Birch, E.E., Garfield, S., Hoffman, D.R., Uauy, R. Birch, D.G. (2000). A randomized controlled trial of early dietary supply of long-chain polyunsaturated fatty acids and mental development in term infants. Developmental Medicine & Child Neurology, 42, 174 181.
    • (2000) Developmental Medicine & Child Neurology , vol.42 , pp. 174-181
    • Birch, E.E.1    Garfield, S.2    Hoffman, D.R.3    Uauy, R.4    Birch, D.G.5
  • 9
    • 0036177755 scopus 로고    scopus 로고
    • A randomized controlled trial of long-chain polyunsaturated fatty acid supplementation of formula in term infants after weaning at 6 weeks of age
    • Birch, E.E., Hoffman, D.R., Castaneda, Y.S., Fawcett, S.L., Birch, D.G. Uauy, R.D. (2002). A randomized controlled trial of long-chain polyunsaturated fatty acid supplementation of formula in term infants after weaning at 6 weeks of age. American Journal of Clinical Nutrition, 75, 570 580.
    • (2002) American Journal of Clinical Nutrition , vol.75 , pp. 570-580
    • Birch, E.E.1    Hoffman, D.R.2    Castaneda, Y.S.3    Fawcett, S.L.4    Birch, D.G.5    Uauy, R.D.6
  • 10
    • 0031871394 scopus 로고    scopus 로고
    • Visual acuity and the essentiality of docosahexaenoic acid and arachidonic acid in the diet of term infants
    • Birch, E.E., Hoffman, D.R., Uauy, R., Birch D.G. Prestidge, C. (1998). Visual acuity and the essentiality of docosahexaenoic acid and arachidonic acid in the diet of term infants. Pediatric Research, 44, 201 209.
    • (1998) Pediatric Research , vol.44 , pp. 201-209
    • Birch, E.E.1    Hoffman, D.R.2    Uauy, R.3    Birch, D.G.4    Prestidge, C.5
  • 12
    • 34848822561 scopus 로고    scopus 로고
    • California WIC Association. (.). Concerns over cost of enhanced formulas to California WIC program. Retrieved April 28, 2004, from
    • California WIC Association. (2003, February). Concerns over cost of enhanced formulas to California WIC program. Retrieved April 28, 2004, from http://www.calwic.org/images/formula_concerns.pdf
    • (2003)
  • 13
    • 0025992888 scopus 로고
    • Long-term feeding of formulas high in linolenic acid and marine oil to very low birth weight infants: Phospholipids fatty acids
    • Carlson, S., Cooke, R., Rhodes, P., Peeples, J., Werkman, S. Tolley, E. (1991). Long-term feeding of formulas high in linolenic acid and marine oil to very low birth weight infants: Phospholipids fatty acids. Pediatric Research, 30, 404 412.
    • (1991) Pediatric Research , vol.30 , pp. 404-412
    • Carlson, S.1    Cooke, R.2    Rhodes, P.3    Peeples, J.4    Werkman, S.5    Tolley, E.6
  • 15
  • 17
    • 34848875758 scopus 로고
    • FAO/WHO/UNU. (.). Expert consultation on fats and oils in human nutrition. Rome, Italy : Food and Agriculture Organization of the United Nations and the World Health Organization.
    • FAO/WHO/UNU. (1994). Expert consultation on fats and oils in human nutrition. Rome, Italy : Food and Agriculture Organization of the United Nations and the World Health Organization.
    • (1994)
  • 18
    • 34848920913 scopus 로고    scopus 로고
    • Fattening the bottom line. (.). Retrieved May 5, 2004, from
    • Fattening the bottom line. (2003, Winter). Retrieved May 5, 2004, from http://www.infactcanada.ca/fattening_the_bottom_line.htm.
    • (2003)
  • 19
    • 34848902050 scopus 로고    scopus 로고
    • Federal Food, Drug, and Cosmetic Act. (n.d.). Requirements for infant formula. Retrieved May 5, 2004, from
    • Federal Food, Drug, and Cosmetic Act. (n.d.). Requirements for infant formula. Retrieved May 5, 2004, from http://www.fda.gov/opacom/laws/fdcact/ fdcact4.htm
  • 20
    • 0027230043 scopus 로고
    • Does the bile salt-stimulated lipase of human milk have a role in the use of the milk long-chain polyunsaturated fatty acids?
    • Hernell, O., Blackberg, L., Chen, Q., Sternby, B. Nilsson, A. (1993). Does the bile salt-stimulated lipase of human milk have a role in the use of the milk long-chain polyunsaturated fatty acids? Journal of Pediatric Gastroenterology and Nutrition, 16, 426 431.
    • (1993) Journal of Pediatric Gastroenterology and Nutrition , vol.16 , pp. 426-431
    • Hernell, O.1    Blackberg, L.2    Chen, Q.3    Sternby, B.4    Nilsson, A.5
  • 21
    • 0026048644 scopus 로고
    • Essential fatty acids in growth and development
    • Innis, S.M. (1991). Essential fatty acids in growth and development. Progress in Lipid Research, 30, 30 103.
    • (1991) Progress in Lipid Research , vol.30 , pp. 30-103
    • Innis, S.M.1
  • 22
    • 0031923484 scopus 로고    scopus 로고
    • Effect of formula supplemented with docosahexaenoic acid and γ-linolenic acid on fatty acid status and visual acuity in term infants
    • Jorgensen, M.H., Holmer, G., Lund, P., Hernall, O. Michaelsen, K.F. (1998). Effect of formula supplemented with docosahexaenoic acid and γ-linolenic acid on fatty acid status and visual acuity in term infants. Journal of Pediatric Gastroenterology and Nutrition, 26, 412 421.
    • (1998) Journal of Pediatric Gastroenterology and Nutrition , vol.26 , pp. 412-421
    • Jorgensen, M.H.1    Holmer, G.2    Lund, P.3    Hernall, O.4    Michaelsen, K.F.5
  • 23
    • 0033524117 scopus 로고    scopus 로고
    • Efficacy and safety of long-chain polyunsaturated fatty acid supplementation of infant-formula milk: A randomized trial
    • Lucas, A., Stafford, M., Morley, R., Abbott, R., Stephenson, T., MacFadyen, U., et al 1999). Efficacy and safety of long-chain polyunsaturated fatty acid supplementation of infant-formula milk: A randomized trial. Lancet, 354, 1948 1954.
    • (1999) Lancet , vol.354 , pp. 1948-1954
    • Lucas, A.1    Stafford, M.2    Morley, R.3    Abbott, R.4    Stephenson, T.5    MacFadyen, U.6    Al, E.7
  • 25
    • 0032865826 scopus 로고    scopus 로고
    • Dietary long-chain polyunsaturated fatty acids do not influence growth of term infants: A randomized clinical trial
    • Makrides, M., Neumann, M.A., Simmer, K. Gibson, R.A. (1999). Dietary long-chain polyunsaturated fatty acids do not influence growth of term infants: A randomized clinical trial. Pediatrics, 104, 468 475.
    • (1999) Pediatrics , vol.104 , pp. 468-475
    • Makrides, M.1    Neumann, M.A.2    Simmer, K.3    Gibson, R.A.4
  • 26
    • 0033982561 scopus 로고    scopus 로고
    • A critical appraisal of the role of dietary long-chain polyunsaturated fatty acids on neural indices of term infants: A randomized, controlled trial
    • Makrides M., Neumann, M.A., Simmer, K. Gibson, R.A. (2000). A critical appraisal of the role of dietary long-chain polyunsaturated fatty acids on neural indices of term infants: A randomized, controlled trial. Pediatrics, 105, 32 38.
    • (2000) Pediatrics , vol.105 , pp. 32-38
    • Makrides, M.1    Neumann, M.A.2    Simmer, K.3    Gibson, R.A.4
  • 27
    • 0026534480 scopus 로고
    • Tissue levels of polyunsaturated fatty acids during early human development
    • Martinez, M. (1992). Tissue levels of polyunsaturated fatty acids during early human development. Journal of Pediatrics, 120 (Suppl. 129 138.
    • (1992) Journal of Pediatrics , vol.120 , pp. 129-138
    • Martinez, M.1
  • 28
    • 0022445141 scopus 로고
    • Biochemical and functional effects of prenatal and postnatal omega-3 fatty acid deficiency on retina and brain in rhesus monkeys
    • Neuringer, M., Connor, W.E., Lin, D.S., Barstad, L. Luck, S. (1986). Biochemical and functional effects of prenatal and postnatal omega-3 fatty acid deficiency on retina and brain in rhesus monkeys. Proceedings of the National Academy of Sciences of the USA, 83, 4021 4025.
    • (1986) Proceedings of the National Academy of Sciences of the USA , vol.83 , pp. 4021-4025
    • Neuringer, M.1    Connor, W.E.2    Lin, D.S.3    Barstad, L.4    Luck, S.5
  • 30
    • 0026470513 scopus 로고
    • Docosahexaenoic acid status of term infants fed breast milk or infant formula containing soy oil or corn oil
    • Ponder, D.L., Innis, S.M., Benson, J.D. Siegman, J.S. (1992). Docosahexaenoic acid status of term infants fed breast milk or infant formula containing soy oil or corn oil. Pediatric Research, 32, 421 426.
    • (1992) Pediatric Research , vol.32 , pp. 421-426
    • Ponder, D.L.1    Innis, S.M.2    Benson, J.D.3    Siegman, J.S.4
  • 31
    • 0031770694 scopus 로고    scopus 로고
    • Assessment of nutrient requirements for infant formulas
    • Raiten, D.J., Talbot, J.M. Waters, J.H. (1998). Assessment of nutrient requirements for infant formulas. Journal of Nutrition, 128 (Suppl. 2089 2109.
    • (1998) Journal of Nutrition , vol.128 , pp. 2089-2109
    • Raiten, D.J.1    Talbot, J.M.2    Waters, J.H.3
  • 32
    • 0036294406 scopus 로고    scopus 로고
    • Prevalence of exclusive breastfeeding among US infants: The third national health and nutrition examination survey
    • Ruowei, L., Ogden, C., Ballew, C., Gillespie, C. Grummer-Strawn, L. (2002). Prevalence of exclusive breastfeeding among US infants: The third national health and nutrition examination survey. American Journal of Public Health, 92, 1107 1110.
    • (2002) American Journal of Public Health , vol.92 , pp. 1107-1110
    • Ruowei, L.1    Ogden, C.2    Ballew, C.3    Gillespie, C.4    Grummer-Strawn, L.5
  • 33
    • 34848885489 scopus 로고    scopus 로고
    • San Diego County Breastfeeding Coalition. (. Retrieved November 6, 2005, from
    • San Diego County Breastfeeding Coalition. (2001). Breastfeeding facts. Retrieved November 6, 2005, from http://www.breastfeeding.org/bfacts/costs.html
    • (2001)
  • 34
    • 3242818918 scopus 로고    scopus 로고
    • Effect of dietary alpha-linolenic acid intake on incorporation of docosahexaenoic and arachidonic acids into plasma phospholipids of term infants
    • Sauerwald, T.U., Hachey, D.L., Jensen, C.L., Anderson, R.E. Heird, W.C. (1996). Effect of dietary alpha-linolenic acid intake on incorporation of docosahexaenoic and arachidonic acids into plasma phospholipids of term infants. Lipids, 31 (Suppl. 131 135.
    • (1996) Lipids , vol.31 , pp. 131-135
    • Sauerwald, T.U.1    Hachey, D.L.2    Jensen, C.L.3    Anderson, R.E.4    Heird, W.C.5
  • 35
    • 0009589805 scopus 로고    scopus 로고
    • Longchain polyunsaturated fatty acid supplementation in infants born at term (Cochrane Review)
    • Simmer, K. (2001). Longchain polyunsaturated fatty acid supplementation in infants born at term (Cochrane Review). The Cochrane Library, 4, 2003.
    • (2001) The Cochrane Library , vol.4 , pp. 2003
    • Simmer, K.1
  • 36
    • 0033977932 scopus 로고    scopus 로고
    • Long chain polyunsaturated fatty acid formation in neonates: Effect of gestational age and intrauterine growth
    • Uauy, R., Mena, P., Wegher, B., Nieto, S. Salem, N. (2000). Long chain polyunsaturated fatty acid formation in neonates: Effect of gestational age and intrauterine growth. Pediatric Research, 47, 127 135.
    • (2000) Pediatric Research , vol.47 , pp. 127-135
    • Uauy, R.1    Mena, P.2    Wegher, B.3    Nieto, S.4    Salem, N.5
  • 37
    • 0024402737 scopus 로고
    • Essential fatty acid metabolism and requirements during development
    • Uauy, R., Treen, M. Hoffman, D.R. (1989). Essential fatty acid metabolism and requirements during development. Seminars in Perinatology, 13, 118 130.
    • (1989) Seminars in Perinatology , vol.13 , pp. 118-130
    • Uauy, R.1    Treen, M.2    Hoffman, D.R.3
  • 38
    • 34848878665 scopus 로고    scopus 로고
    • Retrieved October 26, 2005, from Oregon State University, The Linus Pauling Institute Website:
    • Wander, R. (1998). A primer on dietary fat: The good, the bad and the unknown. Retrieved October 26, 2005, from Oregon State University, The Linus Pauling Institute Website: http://lpi.oregonstate.edu/f-w98/primer.html
    • (1998)
    • Wander, R.1
  • 39
    • 0032578282 scopus 로고    scopus 로고
    • Effect of long-chain polyunsaturated fatty acids in infant formula on problem solving at 10 months of age
    • Willatts, P., Gorsyth, J.S., DiModugno, M.K., Varma, S. Colvin, M. (1998). Effect of long-chain polyunsaturated fatty acids in infant formula on problem solving at 10 months of age. Lancet. 352, 688 691.
    • (1998) Lancet. , vol.352 , pp. 688-691
    • Willatts, P.1    Gorsyth, J.S.2    Dimodugno, M.K.3    Varma, S.4    Colvin, M.5


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