Occurrence of aminoglycoside-modifying-enzyme genes aac(6′)- aph(2″), aph(3′), ant(4′) and ant(6) in clinical isolates of Enterococcus faecalis resistant to high-level of gentamicin and amikacin

Folia Microbiologica

Volumn 51, Issue 1, 2006, Pages 57-61

  Filipova M ^a   Bujdakova H ^a   Drahovskab H ^a   Liskova A ^b   Hanzen, J ^c  

^a Physics and Informatics   (Slovakia)

^b Institute of Clinical Microbiology   (Slovakia)

^c HPL spol s ro   (Slovakia)

Author keywords

[No Author keywords available]

Indexed keywords

6' AMINOGLYCOSIDE ACETYLTRANSFERASE 2'' AMINOGLYCOSIDE PHOSPHOTRANSFERASE; 6'-AMINOGLYCOSIDE ACETYLTRANSFERASE-2''-AMINOGLYCOSIDE PHOSPHOTRANSFERASE; ACYLTRANSFERASE; AMIKACIN; AMINOGLYCOSIDE; ANTIINFECTIVE AGENT; BACTERIAL DNA; GENTAMICIN; NUCLEOTIDYLTRANSFERASE; PHOSPHOTRANSFERASE; STREPTOMYCIN 3'' KINASE; STREPTOMYCIN 3''-KINASE;

ARTICLE; BACTERIAL INFECTION; DRUG EFFECT; ENTEROCOCCUS FAECALIS; ENZYMOLOGY; GENETICS; HUMAN; ISOLATION AND PURIFICATION; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; MULTIDRUG RESISTANCE; POLYMERASE CHAIN REACTION;

ACETYLTRANSFERASES; AMIKACIN; AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; DNA, BACTERIAL; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ENTEROCOCCUS FAECALIS; GENTAMICINS; GRAM-POSITIVE BACTERIAL INFECTIONS; HUMANS; MICROBIAL SENSITIVITY TESTS; NUCLEOTIDYLTRANSFERASES; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); POLYMERASE CHAIN REACTION;

ENTEROCOCCUS FAECALIS; FORMICIDAE;

EID: 33646833596     PISSN: 00155632     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02931451     Document Type: Article

References (25)

1. BARIŠIĆ Z., PUNDA-POLIĆ V.: Antibiotic resistance among enterococcal strains isolated from clinical specimens. Internat.J.Antimicrob. Agents 16, 65-68 (2000).
2. BUJDÁKOVÁ H., KRUPOVÁ I., FILIPOVÁ M., BENZCEOVÁ S., KETTNER M., DRAHOVSKÁ H., SEMAN M., BAGOVÁ M.: The occurrence and transferability of the resistance determinants in 50 amikacin-resistant Enterococcus faecalis and Enterococcus faecium. Internat.J.Antimicrob.Agents 22, 632-633 (2003).
3. DEL CAMPO R., TENORIO C., RUBIO C., CASTILLO J., TORRES C., GOMEZ-LUS R.: Aminoglycoside-modifying enzymes in high-level streptomycin and gentamicin resistant Enterococcus spp. in Spain. J.Antimicrob.Chemother. 15, 221-226 (2000).
4. CHOW J.W.: Aminoglycoside resistance in enterococci. Clin.Infect.Dis. 31, 586-589 (2000).
5. CRITCHLEY I.A., DRAGHI D.C., SAHM D.F., THORNSBERRY C., JONES M.E., KARLOWSKY J.A.: Activity of daptomycin against susceptible and multidrug-resistant Gram-positive pathogens collected in the SECURE study (Europe) during 2000-2001. J.Antimicrob.Chemother. 51, 639-649 (2003).
6. DONABEDIAN S.M., THAL L.A., HERSHBERGER E., PERRI M.B., CHOW J.W., BARTLETT P., JONES R., JOYCE K., ROSSITER S., GAY K., JOHNSON J., MACKINSON C., DEBESS E., MADDEN J., ANGULO F., ZERVOS M.J.: Molecular characterization of gentamicinresistant enterococci in the United States: evidence of spread from animals to humans through food. J.Clin.Microbiol. 41, 1109-1113 (2003).
7. DUTKA-MALEN S., EVERS S., COURVALIN P.: Detection of glycopeptide resistance genotypes and identification to the species level of clinically relevant enterococci by PCR. Antimicrob.Agents Chemother. 33, 24-27 (1995).
8. DE FATIMA SILVA LOPES M., RIBEIRO T., ABRANTES M., FIGUEIREDO MARQUES J.J., TENREIRO R., CRESPO M.T.: Antimicrobial resistance profiles of dairy and clinical isolates and type strains of enterococci. Internat.J.Food.Microbiol 103, 191-198 (2005).
9. FERRETTI J.J., GILMORE K.S., COURVALIN P.: Nucleotide sequence analysis of the gene specifying the bifunctional 6′-aminoglycoside acetyltransferase 2″-aminoglycoside phosphotransferase enzyme in Streptococcus faecalis and identification and cloning of gene regions specifying the two activities. J.Bacteriol. 167, 631-633 (1986).
10. JOS A.M., VAN KLUNDERT D., VLIEGENTHART J.S.: PCR detection of genes coding for aminoglycoside-modifying enzymes, pp. 547-552 in D.H. Persing, T.F. Smith, F.C. Tenover, T.J. White (Eds): Diagnostic Molecular Biology, Principles and Applications. American Society for Microbiology, Washington (DC) 1993.
11. KARLOWSKY J.A., JONES M.E., DRAGHI D.C., THORNSBERRY C., SAHM D.F., VOLTURO G.A.: Prevalence and antimicrobial susceptibilities of bacteria isolated from blood cultures of hospitalized patients in the United States in 2002. Ann.Clin.Microbiol.Antimicrob. 10, 3-7 (2004).
12. KOBAYASHI N., MAHBUB ALAM M.D., NISHIMOTO Y., URASAWA S., UEHARA N., WATANABEN.: Distribution of aminoglycoside resistance genes in recent clinical isolates of Enterococcus faecalis, Enterococcus faecium and Enterococcus avium. Epidemiol. Infectol. 126, 197-204 (2001).
13. MAHBUB ALAM M., KOBAYASHI N., ISHINO M., SUMI A., KOBAYASHI K., UEHARA N., WATANABE N.: Detection of a novel aph(2″) allele (aph[2″]-Ie) conferring high-level gentamicin resistance and a spectinomycin resistance gene ant(9)-Ia (aad 9) in clinical isolates of enterococci. Microb.Drug Resist. 11, 239-247 (2005).
14. MASCHIETO A., MARTINEZ R., PALAZZO I.C., DARINI A.L.: Antimicrobial resistance of Enterococcus sp. isolated from the intestinal tract of patients from a university hospital in Brazil. Mem.Inst.Oswaldo Cruz 99, 763-767 (2004).
15. MURRAY B.E.: The life and times of the Enterococcus. Clin.Microbiol.Rev. 3, 46-65 (1990).
16. NCCLS (National Committee for Clinical Laboratory Standards): Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically, 6th ed. Approved Standard M7-A6. NCCLS, Wayne (USA) 2003a.
17. NCCLS (National Committee for Clinical Laboratory Standards): Performance Standards for Antimicrobial Disk Susceptibility Tests, 8th ed. Approved Standard M2-A8. NCCLS, Wayne (USA) 2003b.
18. RODRIGUEZ-BANO J., RAMIREZ E., MUNIAIN M.A., SANTOS J., JOYANES P., GONZALES F., GARCIA-SANCHEZ M., MARTINEZ-MARTINEZ L.: Colonization by high-level aminoglycoside-resistant enterococci in intensive care unit patients: epidemiology and clinical relevance. J.Hosp.Infect. 60, 353-359 (2005).
19. SLOBODNÍKOVÁ L., KOTULOVÁ D., KLOKOČNÍ KOVÁ D., LONGAUEROVÁ A., ŠVANTNEROVÁ I., BUJDÁKOVÁ H.: Methicillin-resistant staphylococci in patients with skin and wound infections. Biologia 56, 37-42 (2001).
20. SWENSON J.M., FERRARO M.J., SAHM D.F., CLARK N.C., CULVER D.C., TENOVER F.C.: The National Committee for Clinical Laboratory Standards Study Group of Enterococci: multilaboratory evaluation of screening methods for detection of high-level aminoglycoside resistance in enterococci. J.Clin.Microbiol. 33, 3008-3018 (1995).
21. TURNIDGE J., BELL J., BIEDENBACH D.J., JONES R.N.: Pathogen occurrence and antimicrobial resistance among urinary tract infection isolates in the Asia-Western Pacific Region: report from the Sentry Antimicrobial Surveillance Program, 1998-1999. Internat.J.Antimicrob.Agents 20, 10-17 (2002).
22. UDO E.E., AL-SWEIH N., PHILLIPS O.A., CHUGH T.D.: Species prevalence and antibacterial resistance of enterococci isolated in Kuwait hospitals. J.Med.Microbiol. 52, 163-168 (2003).
23. UDO E.E., AL-SWEIH N., JOHN P., JACOB L.E., MOHANAKRISHNAN S.: Characterization of high-level aminoglycoside-resistant enterococci in Kuwait hospitals. Microb.Drug Resist. 10, 139-145 (2004).
24. WAGENLEHNER F.M.E., KRČMÉRY S., HELD C., KLARE I., WITTE W., BAUERNFEIND A., SCHNEIDER I., NABER K.G.: Epidemiological analysis of the spread of pathogens from a urological ward using genotypic, phenotypic and clinical parameters. Internat.J. Antimicrob.Agents 19, 583-591 (2002).
25. ZARRILLI R., TRIPODI M.F., Di POPOLO A., FORTUNATO R., BAGATTINI M., CRISPINO M., FLORIO A., TRIASSI M., UTILI R.: Molecular epidemiology of high-level aminoglycoside-resistant enterococci isolated from patients in a university hospital in southern Italy. J.Antimicrob.Chemother. 56, 827-835 (2005).