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Volumn 9, Issue 5, 2006, Pages 347-353

The impact of parallel chemistry in drug discovery

Author keywords

ADME (absorption, distribution, metabolism and excretion); Automated analysis; Automated synthesis; In silico; Library design; Non combinatorial; Parallel chemistry

Indexed keywords

2 ALKYLTHIOBENZIMIDAZOLE DERIVATIVE; ABELSON KINASE INHIBITOR; BENZIMIDAZOLE DERIVATIVE; DOPAMINE 2 RECEPTOR; DOPAMINE 4 RECEPTOR STIMULATING AGENT; DOPAMINE RECEPTOR STIMULATING AGENT; N' ALKYLBENZIMIDAZOLE 2 ONE DERIVATIVE; NOCICEPTIN RECEPTOR; NOCICEPTIN RECEPTOR AGONIST; NOCICEPTIN RECEPTOR ANTAGONIST; OPIATE RECEPTOR; PIPERIDINE DERIVATIVE; PROTEIN TYROSINE KINASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 33646824373     PISSN: 13697056     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (6)

References (7)
  • 1
    • 3342884458 scopus 로고    scopus 로고
    • Integrating cheminformatic analysis in combinatorial chemistry
    • Blake JF: Integrating cheminformatic analysis in combinatorial chemistry. Curr Opin Chem Biol (2004) 8(4):407-411.
    • (2004) Curr Opin Chem Biol , vol.8 , Issue.4 , pp. 407-411
    • Blake, J.F.1
  • 2
    • 3242888975 scopus 로고    scopus 로고
    • Integrating virtual screening in lead discovery
    • Oprea TI, Matter H: Integrating virtual screening in lead discovery. Curr Opin Chem Biol (2004) 8(4):349-358.
    • (2004) Curr Opin Chem Biol , vol.8 , Issue.4 , pp. 349-358
    • Oprea, T.I.1    Matter, H.2
  • 3
    • 0036761676 scopus 로고    scopus 로고
    • Improvement of "hit-to-lead" optimization by integration of in vitro HTS experimental models for early determination of pharmacokinetic properties
    • Kariv I, Rourick RA, Kassel DB, Chung TD: Improvement of "hit-to-lead" optimization by integration of in vitro HTS experimental models for early determination of pharmacokinetic properties. Comb Chem High Throughput Screen (2002) 5(6):459-472.
    • (2002) Comb Chem High Throughput Screen , vol.5 , Issue.6 , pp. 459-472
    • Kariv, I.1    Rourick, R.A.2    Kassel, D.B.3    Chung, T.D.4
  • 4
    • 12244291911 scopus 로고    scopus 로고
    • Towards a new age of virtual ADME/TOX and multidimensional drug discovery
    • Ekins S, Boulanger B, Swaan PW, Hupcey MA: Towards a new age of virtual ADME/TOX and multidimensional drug discovery. Mol Diversity (2002) 5(4):255-275.
    • (2002) Mol Diversity , vol.5 , Issue.4 , pp. 255-275
    • Ekins, S.1    Boulanger, B.2    Swaan, P.W.3    Hupcey, M.A.4
  • 5
    • 2342486748 scopus 로고    scopus 로고
    • Automation in medicinal chemistry
    • Reader J: Automation in medicinal chemistry. Curr Top Med Chem (2004) 4(7):671-686.
    • (2004) Curr Top Med Chem , vol.4 , Issue.7 , pp. 671-686
    • Reader, J.1
  • 6
    • 3242882808 scopus 로고    scopus 로고
    • High-throughput characterization and quality control of small-molecule combinatorial libraries
    • Kenseth JR, Coldiron SJ: High-throughput characterization and quality control of small-molecule combinatorial libraries. Curr Opin Chem Biol (2004) 8(4):418-423.
    • (2004) Curr Opin Chem Biol , vol.8 , Issue.4 , pp. 418-423
    • Kenseth, J.R.1    Coldiron, S.J.2
  • 7
    • 0035339061 scopus 로고    scopus 로고
    • High-throughput purification of compound libraries
    • Ripka WC, Barker G, Krakover J: High-throughput purification of compound libraries. Drug Disc Today (2001) 6(9):471-477.
    • (2001) Drug Disc Today , vol.6 , Issue.9 , pp. 471-477
    • Ripka, W.C.1    Barker, G.2    Krakover, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.