The putative role of endogenous and exogenous opiates in inflammatory bowel disease

Gut

Volumn 55, Issue 6, 2006, Pages 756-757

  Collins, S ^a,b   Verma Gandhu, M ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY MEDICAL CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ENDORPHIN; CYTOKINE; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST; OPIATE PEPTIDE; TUMOR NECROSIS FACTOR ALPHA; TYROSYL DEXTRO ARGINYLPHENYLALANYLLYSINAMIDE;

CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHRONIC INFLAMMATION; COLITIS; CROHN DISEASE; DIGESTIVE SYSTEM INFLAMMATION; DRUG INHIBITION; DRUG MECHANISM; ENTERITIS; HUMAN; HYPERALGESIA; LAMINA PROPRIA; MONONUCLEAR CELL; NONHUMAN; NOTE; PAIN THRESHOLD; PRIORITY JOURNAL; RECEPTOR UPREGULATION; ULCERATIVE COLITIS;

ANALGESICS, OPIOID; ANIMALS; BETA-ENDORPHIN; HUMANS; INFLAMMATORY BOWEL DISEASES; MICE; RECEPTORS, OPIOID, MU; UP-REGULATION;

EID: 33646822074     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.2005.084418     Document Type: Note

References (26)

1. Philippe D, Chakass D, Thuru X, et al. Mu opioid receptor expression is increased in inflammatory bowel diseases: implications for homeostatic intestinal inflammation. Gut 2006;55:815-23.
2. Philippe D, Dubuquoy L, Groux H, et al. Anti-inflammatory properties of the mu opioid receptor support its use in the treatment of colon inflammation. J Clin Invest 2003;111:1329-38.
3. Yamamoto H, Morise K, Kusugami K, et al. Abnormal neuropeptide concentration in rectal mucosa of patients with inflammatory bowel disease. J Gastroenterol 1996;31:525-32.
4. Neunlist M, Aubert P, Toquet C, et al. Changes in chemical coding of myenteric neurones in ulcerative colitis. Gut 2003;52:84-90.
5. Chen X, McClatchy DB, Geller EB, et al. The dynamic relationship between mu and kappa opioid receptors in body temperature regulation. Life Sci 2005;78:329-33.
6. Chen ZC, Kuo JR, Huang YP, et al. mu-Opioid receptor blockade protects against circulatory shock and cerebral ischemia during heatstroke. J Cardiovasc Pharmacol 2005;46:754-60.
7. Meisel H, FitzGerald RJ. Opioid peptides encrypted in intact milk protein sequences. Br J Nutr 2000;84(suppl 1):S27-31.
8. Teschemacher H. Opioid receptor ligands derived from food proteins. Curr Pharm Des 2003;9:1331-44.
9. Elitsur Y, Luk GD. Beta-casomorphin (BCM) and human colonic lamina propria lymphocyte proliferation. Clin Exp Immunol 1991;85:493-7.
10. Cashman KD, Shanahan F. Is nutrition an aetiological factor for inflammatory bowel disease? Eur J Gastroenterol Hepatol 2003;15:607-13.
11. Mishkin S. Dairy sensitivity, lactose malabsorption, and elimination diets in inflammatory bowel disease. Am J Clin Nutr 1997;65:564-7.
12. Crivellato E, Soldano F, Travan L. A light and electron microscopic quantitative analysis of nerve-immune cell contacts in the gut-associated lymphoid tissue of the mouse colon. J Submicrosc Cytol Pathol 2002;34:55-66.
13. Sternini C, Patierno S, Selmer IS, et al. The opioid system in the gastrointestinal tract. Neurogastroenterol Motil 2004;16(suppl 2):3-16.
14. Engel GL. Studies of ulcerative colitis. II. The nature of the somatic processes and the adequacy of psychosomatic hypotheses. Am J Med 1954;16:416-33.
15. Sim M, Brooke BN. Ulcerative colitis; a test of psychosomatic hypotheses. Lancet 1958;2:125-6.
16. Kovelaars A, Ballieux RE, Heijnen CJ. In vitro beta-adrenergic stimulation or lymphocytes induces the release of immunoreactive beta-endorphin. Endocrinology 1990;126:3028-32.
17. Kavelaars A, Berkenbosch F, Croiset G, et al. Induction of beta-endorphin secretion by lymphocytes after subcutaneous administration of corticotropin-releasing factor. Endocrinology 1990;126:759-64.
18. Kavelaars A, Ballieux RE, Heijnen CJ. Beta-endorphin secretion by human peripheral blood mononuclear cells: regulation by glucocorticoids. Life Sci 1990;46:1233-40.
19. Stein C, Hassan AH, Przewocki R, et al. Opioids from immunocytes interact with receptors on sensory nerves to inhibit nociception in inflammation. Proc Natl Acad Sci U S A 1990;87:5935-9.
20. Verma-Gandhu M, Bercik P, Motomura Y, et al. Immune cells modulate visceral pain by endogenous opioid production. Gastroenterology 2005;128(suppl 2):A225.
21. Farthing MJ, Lennard-Jones JE. Sensibility of the rectum to distension and the anorectal distension reflex in ulcerative colitis. Gut 1978;19:64-9.
22. Mayer EA, Berman S, Suyenobu B, et al. Differences in brain responses to visceral pain between patients with irritable bowel syndrome and ulcerative colitis. Pain 2005;115:398-409.
23. Bernstein CN, Niazi N, Robert M, et al. Rectal afferent function in patients with inflammatory and functional intestinal disorders. Pain 1996;66:151-61.
24. Kern F Jr, Almy TP, Abbot FK, et al. The motility of the distal colon in non specific ulcerative colitis. Gastroenterology 1951;19:492-503.
25. Garrett JM, Sauer WG, Moertel CG. Colonic motility in ulcerative colitis after opiate administration. Gastroenterology 1967;53:93-100.
26. Edwards JT, Radford-Smith GL, Florin TH. Chronic narcotic use in inflammatory bowel disease patients: prevalence and clinical characteristics. J Gastroenterol Hepatol 2001;16:1235-8.