Effects of aging on BOLD fMRI during prosaccades and antisaccades

Journal of Cognitive Neuroscience

Volumn 18, Issue 4, 2006, Pages 594-603

  Raemaekers, M ^a,b   Vink, M ^a   Van Den Heuvel, M P ^a   Kahn, R S ^a   Ramsey, N F ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b HP A01126 ^*  (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGING; BRAIN MAPPING; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; INHIBITION (PSYCHOLOGY); MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; OXYGEN; REACTION TIME; SACCADES; VISUAL CORTEX;

EID: 33646817117     PISSN: 0898929X     EISSN: 15308898     Source Type: Journal    
DOI: 10.1162/jocn.2006.18.4.594     Document Type: Article

References (53)

1. Abel, L. A., Troost, B. T., & Dell'Osso, L. F. (1983). The effects of age on normal saccadic characteristics and their variability. Vision Research, 23, 33-37.
2. Adler, C. M., Holland, S. K., Enseleit, S., & Strakowski, S. M. (2001). Age-related changes in regional activation during working memory in young adults: An fMRI study. Synapse, 42, 252-257.
3. Aizenstein, H. J., Clark, K. A., Butters, M. A., Cochran, J., Stenger, V. A., Meltzer, C. C., Reynolds, C. F., & Carter, C. S. (2004). The BOLD hemodynamic response in healthy aging. Journal of Cognitive Neuroscience, 16, 786-793.
4. Bandettini, P. A., & Cox, R. W. (2000). Event-related fMRI contrast when using constant interstimulus interval: Theory and experiment. Magnetic Resonance in Medicine, 43, 540-548.
5. Berthoz, A. (1996). The role of inhibition in the hierarchical gating of executed and imagined movements. Brain Research, Cognitive Brain Research, 3, 101-113.
6. Buijs, P. C., Krabbe-Hartkamp, M. J., Bakker, C. J., de Lange, E. E., Ramos, L. M., Breteler, M. M., & Mali, W. P. (1998). Effect of age on cerebral blood flow: Measurement with ungated two-dimensional phase-contrast MR angiography in 250 adults. Radiology, 209, 667-674.
7. Butler, K. M., Zacks, R. T., & Henderson, J. M. (1999). Suppression of reflexive saccades in younger and older adults: Age comparisons on an antisaccade task. Memory & Cognition, 27, 584-591.
8. Cabeza, R. (2002). Hemispheric asymmetry reduction in older adults: The HAROLD model. Psychology and Aging, 17, 85-100.
9. Cabeza, R., Anderson, N. D., Locantore, J. K., & McIntosh, A. R. (2002). Aging gracefully: Compensatory brain activity in high-performing older adults. Neuroimage, 17, 1394-1402.
10. Carter, J. E., Obler, L., Woodward, S., & Albert, M. L. (1983). The effect of increasing age on the latency for saccadic eye movements. Journal of Gerontology, 38, 318-320.
11. Collins, D. L., Neelin, P., Peters, T. M., & Evans, A. C. (1994). Automatic 3D intersubject registration of MR volumetric data in standardized Talairach space. Journal of Computer Assisted Tomography, 18, 192-205.
12. Cornelissen, F. W., Kimmig, H., Schira, M., Rutschmann, R. M., Maguire, R. P., Broerse, A., Den Boer, J. A., & Greenlee, M. W. (2002). Event-related fMRI responses in the human frontal eye fields in a randomized pro- and antisaccade task. Experimental Brain Research, 145, 270-274.
13. Desouza, J. F., Menon, R. S., & Everling, S. (2003). Preparatory set associated with pro-saccades and anti-saccades in humans investigated with event-related fMRI. Journal of Neurophysiology, 89, 1016-1023.
14. D'Esposito, M., Deouell, L. Y., & Gazzaley, A. (2003). Alterations in the BOLD fMRI signal with ageing and disease: A challenge for neuroimaging. Nature Reviews Neuroscience, 4, 863-872.
15. D'Esposito, M., Zarahn, E., Aguirre, G. K., & Rypma, B. (1999). The effect of normal aging on the coupling of neural activity to the bold hemodynamic response. Neuroimage, 10, 6-14.
16. Eenshuistra, R. M., Ridderinkhof, K. R., & van der Molen, M. W. (2004). Age-related changes in antisaccade task performance: Inhibitory control or working-memory engagement? Brain and Cognition, 56, 177-188.
17. Evdokimidis, I., Smyrnis, N., Constantinidis, T. S., Stefanis, N. C., Avramopoulos, D., Paximadis, C., Theleritis, C., Efstratiadis, C., Kastrinakis, G., & Stefanis, C. N. (2002). The antisaccade task in a sample of 2,006 young men. I. Normal population characteristics. Experimental Brain Research, 147, 45-52.
18. Fischer, B., Biscaldi, M., & Gezeck, S. (1997). On the development of voluntary and reflexive components in human saccade generation. Brain Research, 754, 285-297.
19. Friston, K. J., Frith, C. D., Turner, R., & Frackowiak, R. S. (1995). Characterizing evoked hemodynamics with fMRI. Neuroimage, 2, 157-165.
20. Ge, Y., Grossman, R. I., Babb, J. S., Rabin, M. L., Mannon, L. J., & Kolson, D. L. (2002). Age-related total gray matter and white matter changes in normal adult brain. Part I: Volumetric MR imaging analysis. AJNR, American Journal of Neuroradiology, 23, 1327-1333.
21. Grosbras, M. H., Leonards, U., Lobel, E., Poline, J. B., LeBihan, D., & Berthoz, A. (2001). Human cortical networks for new and familiar sequences of saccades. Cerebral Cortex, 11, 936-945.
22. Hallett, P. E. (1978). Primary and secondary saccades to goals defined by instructions. Vision Research, 18, 1279-1296.
23. Hedden, T., & Gabrieli, J. D. (2004). Insights into the ageing mind: A view from cognitive neuroscience. Nature Reviews Neuroscience, 5, 87-96.
24. Hesselmann, V., Zaro, W. O., Wedekind, C., Krings, T., Schulte, O., Kugel, H., Krug, B., Klug, N., & Lackner, K. J. (2001). Age related signal decrease in functional magnetic resonance imaging during motor stimulation in humans. Neuroscience Letters, 308, 141-144.
25. Huettel, S. A., Singerman, J. D., & McCarthy, G. (2001). The effects of aging upon the hemodynamic response measured by functional MRI. Neuroimage, 13, 161-175.
26. Iidaka, T., Okada, T., Murata, T., Omori, M., Kosaka, H., Sadato, N., & Yonekura, Y. (2002). Age-related differences in the medial temporal lobe responses to emotional faces as revealed by fMRI. Hippocampus, 12, 352-362.
27. Kimmig, H., Greenlee, M. W., Gondan, M., Schira, M., Kassubek, J., & Mergner, T. (2001). Relationship between saccadic eye movements and cortical activity as measured by fMRI: Quantitative and qualitative aspects. Experimental Brain Research, 141, 184-194.
28. Kimmig, H., Greenlee, M. W., Huethe, F., & Mergner, T. (1999). MR-eyetracker: A new method for eye movement recording in functional magnetic resonance imaging. Experimental Brain Research, 126, 443-449.
29. Klein, C., Fischer, B., Hartnegg, K., Heiss, W. H., & Roth, M. (2000). Optomotor and neuropsychological performance in old age. Experimental Brain Research, 135, 141-154.
30. Langenecker, S. A., & Nielson, K. A. (2003). Frontal recruitment during response inhibition in older adults replicated with fMRI. Neuroimage, 20, 1384-1392.
31. Langenecker, S. A., Nielson, K. A., & Rao, S. M. (2004). fMRI of healthy older adults during Stroop interference. Neuroimage, 21, 192-200.
32. Larsson, A., Skoog, I., Aevarsson, Arlig, A., Jacobsson, L., Larsson, L., Ostling, S., & Wikkelso, C. (2001). Regional cerebral blood flow in normal individuals aged 40, 75 and 88 years studied by 99Tc(m)-d,l-HMPAO SPET. Nuclear Medicine Communications, 22, 741-746.
33. Matsue, Y., Saito, H., Osakabe, K., Awata, S., Ueno, T., Matsuoka, H., Chiba, H., Fuse, Y., & Sato, M. (1994). Smooth pursuit eye movements and voluntary control of saccades in the antisaccade task in schizophrenic patients. Japanese Journal of Psychiatry and Neurology, 48, 13-22.
34. Mehagnoul-Schipper, D. J., van der Kallen, B. F., Colier, W. N., van der Sluijs, M. C., van Erning, L. J., Thijssen, H. O., Oeseburg, B., Hoefnagels, W. H., & Jansen, R. W. (2002). Simultaneous measurements of cerebral oxygenation changes during brain activation by near-infrared spectroscopy and functional magnetic resonance imaging in healthy young and elderly subjects. Human Brain Mapping, 16, 14-23.
35. Milham, M. P., Erickson, K. I., Banich, M. T., Kramer, A. F., Webb, A., Wszalek, T., & Cohen, N. J. (2002). Attentional control in the aging brain: Insights from an fMRI study of the Stroop task. Brain and Cognition, 49, 277-296.
36. Munoz, D. P., Broughton, J. R., Goldring, J. E., & Armstrong, I. T. (1998). Age-related performance of human subjects on saccadic eye movement tasks. Experimental Brain Research, 121, 391-400.
37. Muri, R. M., Heid, O., Nirkko, A. C., Ozdoba, C., Felblinger, J., Schroth, G., & Hess, C. W. (1998). Functional organisation of saccades and antisaccades in the frontal lobe in humans: A study with echo planar functional magnetic resonance imaging. Journal of Neurology, Neurosurgery and Psychiatry, 65, 374-377.
38. Nielson, K. A., Langenecker, S. A., & Garavan, H. (2002). Differences in the functional neuroanatomy of inhibitory control across the adult life span. Psychology and Aging, 17, 56-71.
39. Nieuwenhuis, S., Ridderinkhof, K. R., de Jong, R., Kok, A., & van der Molen, M. W. (2000). Inhibitory inefficiency and failures of intention activation: Age-related decline in the control of saccadic eye movements. Psychology and Aging, 15, 635-647.
40. Oldfield, R. C. (1971). The assessment and analysis of handedness: The Edinburgh inventory. Neuropsychologia, 9, 97-113.
41. Olincy, A., Ross, R. G., Youngd, D. A., & Freedman, R. (1997). Age diminishes performance on an antisaccade eye movement task. Neurobiology of Aging, 18, 483-489.
42. Pierrot-Deseilligny, C., Rivaud, S., Gaymard, B., & Agid, Y. (1991). Cortical control of reflexive visually-guided saccades. Brain, 114, 1473-1485.
43. Raemaekers, M., Jansma, J. M., Cahn, W., Van der Geest, J. N., van der Linden, J. A., Kahn, R. S., & Ramsey, N. F. (2002). Neuronal substrate of the saccadic inhibition deficit in schizophrenia investigated with 3-dimensional event-related functional magnetic resonance imaging. Archives of General Psychiatry, 59, 313-320.
44. Ramsey, N. F., van den Brink, J. S., van Muiswinkel, A. M., Folkers, P. J., Moonen, C. T., Jansma, J. M., & Kahn, R. S. (1998). Phase navigator correction in 3D fMRI improves detection of brain activation: Quantitative assessment with a graded motor activation procedure. Neuroimage, 8, 240-248.
45. Rutten, G. J., Ramsey, N. F., van Rijen, P. C., & van Veelen, C. W. (2002). Reproducibility of fMRI-determined language lateralization in individual subjects. Brain and Language, 80, 421-437.
46. Scahill, R. I., Frost, C., Jenkins, R., Whitwell, J. L., Rossor, M. N., & Fox, N. C. (2003). A longitudinal study of brain volume changes in normal aging using serial registered magnetic resonance imaging. Archives of Neurology, 60, 989-994.
47. Shafiq-Antonacci, R., Maruff, P., Masters, C., & Currie, J. (2003). Spectrum of saccade system function in Alzheimer disease. Archives of Neurology, 60, 1272-1278.
48. Sweeney, J. A., Mintun, M. A., Kwee, S., Wiseman, M. B., Brown, D. L., Rosenberg, D. R., & Carl, J. R. (1996). Positron emission tomography study of voluntary saccadic eye movements and spatial working memory. Journal of Neurophysiology, 75, 454-468.
49. Sweeney, J. A., Rosano, C., Berman, R. A., & Luna, B. (2001). Inhibitory control of attention declines more than working memory during normal aging. Neurobiology of Aging, 22, 39-47.
50. Tedeschi, G., Di Costanzo, A., Allocca, S., Quattrone, A., Casucci, G., Russo, L., & Bonavita, V. (1989). Age-dependent changes in visually guided saccadic eye movements. Functional Neurology, 4, 363-367.
51. Thevenaz, P., Ruttimann, U. E., & Unser, M. (1998). Pyramid approach to subpixel registration based on intensity. IEEE Transactions on Image Processing, 7, 27-41.
52. Van Gelderen, P., Ramsey, N. F., Liu, G., Duyn, J. H., Frank, J. A., Weinberger, D. R., & Moonen, C. T. (1995). Three-dimensional functional magnetic resonance imaging of human brain on a clinical 1.5-T scanner. Proceedings of the National Academy of Sciences, U.S.A., 92, 6906-6910.
53. 2, F and t fields. Advances in Applied Probability, 13-42.