Nonsteroidal progesterone receptor ligands (I): Synthesis and SAR of new tetrahydronaphthofuranone derivatives

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 14, 2006, Pages 4850-4861

  Shinei, Rie ^a   Kurihara, Ken ichi ^a   Tanabe, Kiyoshi ^a   Tabata, Yuji ^a   Kurata, Yasushi ^a   Hoshiko, Shigeru ^a   Okonogi, Tsuneo ^a  

^a MEIJI SEIKA KAISHA LTD   (Japan)

Author keywords

Nonsteroidal progesterone receptor ligands; PF1092; PR antagonist; Tetrahydronaphthofuranone

Indexed keywords

6 CYCLOPROPYLAMINOCARBOYLOXY 7 METHOXY 4A,5,6,7 TETRAHYDRO 3,4A,5 TRIMETHYLNAPHTHO[2,3 B]FURAN 2(4H) ONE; ANTIGESTAGEN; FURANONE DERIVATIVE; HYDROXYL GROUP; PF 1092A; PF 1092B; PF 1092C; STEROID RECEPTOR; TETRAHYDRONAPHTHOFURANONE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG STRUCTURE; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION;

CELL LINE; FURANS; HORMONE ANTAGONISTS; HUMANS; KINETICS; LIGANDS; NAPHTHOLS; RECEPTORS, PROGESTERONE; SESQUITERPENES; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAHYDRONAPHTHALENES;

EID: 33646813592     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.03.018     Document Type: Article

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