Danger of flumazenil use in pediatric status epilepticus

Pediatric Emergency Care

Volumn 22, Issue 3, 2006, Pages 168-169

  Brierley, Joe ^a,b  

^a GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^b Great Ormond Street Hospital for Children NHS Trust ^*  (United Kingdom)

Author keywords

Flumazenil; Pediatric status epilepticus; Respiratory depression

Indexed keywords

BENZODIAZEPINE DERIVATIVE; CLOBAZAM; DIAZEPAM; FLUMAZENIL; LORAZEPAM; MIDAZOLAM; PHENYTOIN; THIOPENTAL;

ARTICLE; ARTIFICIAL VENTILATION; CASE REPORT; COMMON COLD; EPILEPTIC STATE; EXTUBATION; FEBRILE CONVULSION; FEMALE; FEVER; GRAND MAL SEIZURE; HUMAN; INTERMITTENT POSITIVE PRESSURE VENTILATION; MALE; PEDIATRICS; PRESCHOOL CHILD; RECURRENT DISEASE; RESPIRATION DEPRESSION; TONIC CLONIC SEIZURE;

BENZODIAZEPINES; CHILD, PRESCHOOL; FEMALE; FLUMAZENIL; HUMANS; INFANT; MALE; RECURRENCE; RESPIRATORY INSUFFICIENCY; STATUS EPILEPTICUS;

EID: 33646813348     PISSN: 07495161     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.pec.0000202458.72602.85     Document Type: Article

References (13)

1. Wieteska S, Mackway-Jones K, Phillips B, eds. Advance Paediatric Life Support: the practical approach. London, UK: BMJ Books; December 31, 2004.
2. The Status Epilepticus Working Party, Members of the Status Epilepticus Working Party, Appleton R, Choonara I, Martland T, et al. The treatment of convulsive status epilepticus in children. Arch Dis Child. 2000;83:415-419.
3. Chin RF, Verhulst L, Neville BG, et al. Inappropriate emergency management of status epilepticus in children contributes to need for intensive care. Neural Neurosurg Psychiatry. November 2004;75(11): 1584-1588.
4. Galustyan SG, Walsh-Kelly CM, Szewczuga D, et al. The short-term outcome of seizure management by prehospital personnel: a comparison of two protocols. Pediatr Emerg Care. August 2003;19(4):221-225.
5. Paediatric Intensive Care. "A Framework for the Future" National Coordinating Group on Paediatric Intensive Care. Report to the chief executive of the NHS executive. Crown Copyright Produced by Department of Health 11004 HCD 700 1P July 1997:(3).
6. Doble A. New insights into the mechanism of action of hypnotics. J Psychopharmacol. 1999;13(4 suppl 1):S11-S20.
7. Playfor SD, Thomas DA, Choonara I. Sedation and neuromuscular blockade in paediatric intensive care: a review of current practice in the UK. Paediatr Anaesth. February 2003;13(2):147-151.
8. Nordt SP, Clark RF. Midazolam: a review of therapeutic uses and toxicity. J Emerg Med. May-June 1997;15(3):357-365.
9. Lauven PM, Calaminus JM. Antagonists in anesthesia. Anasthesiol Intensivmed Notfallmed Schmerzther. October 1995;30(6):331-336.
10. Spivey WH. Flumazenil and seizures: analysis of 43 cases. Clin Ther. March-April 1992;14(2):292-305.
11. Proudfoot AT. Antidotes: benefits and risks. Toxicol Lett. December 1995;82-83:779-783.
12. McDuffee AT, Tobias JD. Seizure after flumazenil administration in a pediatric patient. Pediatr Emerg Care. June 1995;11(3):186-187.
13. Davis CO, Wax PM. Flumazenil associated seizure in an 11-month-old child. J Emerg Med. May-June 1996;14(3):331-333.