Resistance of different Chlamydia-like organisms to quinolones and mutations in the quinoline resistance-determining region of the DNA gyrase A- and topoisomerase-encoding genes

International Journal of Antimicrobial Agents

Volumn 27, Issue 6, 2006, Pages 541-544

  Casson, Nicola ^a   Greub, Gilbert ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

Chlamydia; Chlamydia like organisms; DNA gyrase; QRDR; Quinolones; Topoisomerase

Indexed keywords

CIPROFLOXACIN; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING) A; QUINOLONE DERIVATIVE;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ARTICLE; CHLAMYDIA; DNA SEQUENCE; GENE AMPLIFICATION; GENE MUTATION; NEOCHLAMYDIA HARTMANNELLAE; NONHUMAN; PRIORITY JOURNAL; SIMKANIA NEGEVENSIS;

AMINO ACID SEQUENCE; ANTI-INFECTIVE AGENTS; CHLAMYDIA; CIPROFLOXACIN; DNA GYRASE; DNA TOPOISOMERASE IV; DRUG RESISTANCE, BACTERIAL; MOLECULAR SEQUENCE DATA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33646812528     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2006.03.009     Document Type: Article

References (18)

1. Birtles R.J., Rowbotham T.J., Storey C., Marrie T.J., and Raoult D. Chlamydia-like obligate parasite of free-living amoebae. Lancet 349 (1997) 925-926
2. Greub G., and Raoult D. Parachlamydiaceae: potential emerging pathogens. Emerg Infect Dis 8 (2002) 625-630
3. Corsaro D., and Greub G. Pathogenic potential of novel chlamydiae and diagnostic approaches to infections due to these obligate intracellular bacteria. Clin Microbiol Rev 19 (2006) 283-297
4. Marrie T.J., Raoult D., La Scola B., Birtles R.J., and de Carolis E. Legionella-like and other amoebal pathogens as agents of community-acquired pneumonia. Emerg Infect Dis 7 (2001) 1026-1029
5. Greub G., Boyadjiev I., La Scola B., Raoult D., and Martin C. Serological hint suggesting that Parachlamydiaceae are agents of pneumonia in polytraumatized intensive care patients. Ann N Y Acad Sci 990 (2003) 311-319
6. Greub G., Berger P., Papazian L., and Raoult D. Parachlamydiaceae as rare agents of pneumonia. Emerg Infect Dis 9 (2003) 755-756
7. Greub G., Mege J.L., and Raoult D. Parachlamydia acanthamoebae enters and multiplies within human macrophages and induces their apoptosis. Infect Immun 71 (2003) 5979-5985
8. Greub G., Mege J.L., Gorvel J.P., Raoult D., and Meresse S. Intracellular trafficking of Parachlamydia acanthamoebae. Cell Microbiol 7 (2005) 581-589
9. Friedman M.G., Dvoskin B., and Kahane S. Infections with the Chlamydia-like microorganism Simkania negevensis, a possible emerging pathogen. Microbes Infect 5 (2003) 1013-1021
10. Maurin M., Bryskier A., and Raoult D. Antibiotic susceptibilities of Parachlamydia acanthamoeba in amoebae. Antimicrob Agents Chemother 46 (2002) 3065-3067
11. Vila J., Ruiz J., Marco F., et al. Association between double mutation in gyrA gene of ciprofloxacin-resistant clinical isolates of Escherichia coli and MICs. Antimicrob Agents Chemother 38 (1994) 2477-2479
12. Dessus-Babus S., Bebear C.M., Charron A., Bebear C., and de Barbeyrac B. Sequencing of gyrase and topoisomerase IV quinoline resistance-determining regions of Chlamydia trachomatis and characterization of quinolone-resistant mutants obtained In vitro. Antimicrob Agents Chemother 42 (1998) 2474-2481
13. Rupp J., Gebert A., Solbach W., and Maass M. Serine-to-asparagine substitution in the gyrA gene leads to quinolone resistance in moxifloxacin-exposed Chlamydia pneumoniae. Antimicrob Agents Chemother 49 (2005) 406-407
14. Drlica K., and Zhao X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev 61 (1997) 377-392
15. Maurin M., Abergel C., and Raoult D. DNA gyrase-mediated natural resistance to fluoroquinolones in Ehrlichia spp. Antimicrob Agents Chemother 45 (2001) 2098-2105
16. Nakamura M. Mechanisms of quinolone resistance. J Infect Chemother (1997) 128-138
17. Huang W.M. Bacterial diversity based on type II DNA topoisomerase genes. Annu Rev Genet 30 (1996) 79-107
18. Yokoi S., Yasuda M., Ito S., et al. Uncommon occurrence of fluoroquinolone resistance-associated alterations in GyrA and ParC in clinical strains of Chlamydia trachomatis. J Infect Chemother 10 (2004) 262-267