Tissue distribution and plasma clearance of heparin-binding EGF-like growth factor (HB-EGF) in adult and newborn rats

Peptides

Volumn 27, Issue 6, 2006, Pages 1589-1596

  Feng, Jiexiong ^a   Mehta, Veela B ^a   El Assal, Osama N ^a   Wu, Dan ^a   Besner, Gail E ^a  

^a THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

Author keywords

HB EGF; Pharmacokinetics; Tissue distribution

Indexed keywords

HEPARIN BINDING EPIDERMAL GROWTH FACTOR; IODINE 125;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE; BINDING AFFINITY; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG URINE LEVEL; EPITHELIUM CELL; INTESTINE CELL; INTESTINE INJURY; INTESTINE ISCHEMIA; KIDNEY; LIVER; MALE; NEWBORN; NONHUMAN; PLASMA CLEARANCE; PRIORITY JOURNAL; RADIATION DETECTION; RAT; TISSUE DISTRIBUTION;

ANIMALS; ANIMALS, NEWBORN; EPIDERMAL GROWTH FACTOR; GASTROINTESTINAL DISEASES; KINETICS; MALE; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 33646803448     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2005.11.013     Document Type: Article

References (25)

1. Besner G.E., Higashiyama S., and Klagsbrun M. Isolation and characterization of a macrophage-derived heparin-binding growth factor. Cell Regul 1 (1990) 811-819
2. Burwen S.J., Barker M.E., Goldman I.S., and Jones A.L. The effect of concentration on hepatic transport of exogenous epidermal growth factor. Hepatology 5 (1985) 211-214
3. Davis K.M., Brigstock D.R., Johnson P.R., Crissman-Combs M.A., McCarthy D.W., Downing M.T., et al. Production of glycosylated heparin-binding EGF-like growth factor in HeLa cells using vaccinia virus. Protein Express Purif 8 (1996) 57-67
4. Davis-Fleischer K.M., and Besner G.E. Structure and function of heparin-binding EGF-like growth factor (HB-EGF). Front Biosci 3 (1998) d288-d299
5. Dunn W.A., and Hubbard A.L. Receptor-mediated endocytosis of epidermal growth factor by hepatocytes in the perfused rat liver: ligand and receptor dynamics. J Cell Biol 98 (1984) 2148-2159
6. El-Assal O.N., and Besner G.E. Heparin-binding epidermal growth factor-like growth factor and intestinal ischemia-reperfusion injury. Semin Pediatr Surg 13 (2004) 2-10
7. Feng J., El-Assal O.N., and Besner G.E. Heparin-binding EGF-like growth factor (HB-EGF) and necrotizing enterocolitis. Semin Pediatr Surg 14 (2005) 167-174
8. Feng J, El-Assal ON, Besner GE. Heparin-binding EGF-like growth factor (HB-EGF) decreases the incidence of necrotizing enterocolitis in neonatal rats. J Pediatr Surg (in press).
9. Higashiyama S., Abraham J.A., Miller J.C., Fiddes J.C., and Klagsbrun M. A heparin-binding EGF-like growth factor secreted by macrophage-like cells that is related to epidermal growth factor. Science 251 (1991) 936-939
10. Kim D.C., Sugiyama Y., Fuwa T., Sakamoto S., Iga T., and Hanano M. Kinetic analysis of the elimination process of human epidermal growth factor (hEGF) in rats. Biochem Pharmacol 38 (1989) 241-249
11. Kim D.C., Sugiyama Y., Satoh H., Fuwa T., Iga T., and Hanano M. Kinetic analysis of in vivo receptor dependent binding of human epidermal growth factor by rat tissues. J Pharm Sci 77 (1988) 200-207
12. Kimura T., Murakawa Y., Ohno M., Ohtani S., and Higaki K. Gastrointestinal absorption of recombinant human insulin-like growth factor-I in rats. J Pharmcol Exp Ther 283 (1997) 611-618
13. Kong W.Y., Koldovsky O., and Rao R.K. Appearance of exogenous epidermal growth factor in liver, bile, and intestinal lumen of suckling rats. Gastroenterology 102 (1992) 661-667
14. Kuo B.S., Kusmik W.F., Poole J.C., Elsea S.H., Chang J., and Hwang K.K. Pharmacokinetic evaluation of two human epidermal growth factors (hEGF51 and hEGF53) in rats. Drug Metab Dispos 20 (1992) 23-30
15. Kuo B.S., Nordblom G.D., and Wright D.S. Perturbation of epidermal growth factor clearance after radioiodination and its implications. J Pharm Sci 86 (1997) 290-296
16. Pan W., and Kastin A.J. Entry of EGF into brain is rapid and saturable. Peptides 20 (1999) 1091-1098
17. Shen W.H., and Xu R.J. Stability of epidermal growth factor in the gastrointestinal lumen of suckling and weaned pigs. Life Sci 59 (1996) 197-208
18. Shen W.H., and Xu R.J. Stability and distribution of orally administered epidermal growth factor in neonatal pigs. Life Sci 63 (1998) 809-820
19. Sonksen P.H., Tompkins C.V., Srivastava M.C., and Nabarro J.D. A comparative study on the metabolism of human insulin and porcine proinsulin in man. Clin Sci Mol Med 45 (1973) 633-654
20. St Hilaire R.J., Hradek G.T., and Jones A.L. Hepatic sequestration and biliary secretion of epidermal growth factor: evidence for a high-capacity uptake system. Proc Natl Acad Sci USA 80 (1983) 3797-3801
21. St Hilaire R.J., and Jones A.L. Epidermal growth factor: its biologic and metabolic effects with emphasis on the hepatocyte. Hepatology 2 (1982) 601-613
22. Sugiyama Y., and Hanano M. Receptor-mediated transport of peptide hormones and its importance in the overall hormone disposition in the body. Pharmacol Res 6 (1989) 192-202
23. Tyson L.M., Browne C.A., Jenkin G., and Thorburn G.D. The fate and uptake of murine epidermal growth factor in the sheep. J Endocrinol 123 (1989) 121-130
24. Yachi K., Sugiyama Y., Sato H., Kim D.C., Fuwa T., Iga T., et al. Comparison of specific binding of human epidermal growth factor (EGF) to sinusoidal and bile canalicular membranes isolated from rat liver. J Biochem (Tokyo) 103 (1988) 448-451
25. Yanai S., Sugiyama Y., Kim D.C., Sato H., Fuwa T., Iga T., et al. Binding of human epidermal growth factor to tissue homogenates of the rat. Chem Pharm Bull (Tokyo) 35 (1987) 4891-4897